Gene Information

Name : afeA (BARBAKC583_1311)
Accession : YP_989559.1
Strain : Bartonella bacilliformis KC583
Genome accession: NC_008783
Putative virulence/resistance : Virulence
Product : iron chelate ABC transporter, periplasmic iron chelate-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 1363326 - 1364234 bp
Length : 909 bp
Strand : -
Note : similarity to yfeA of Yersinia pestis; identified by similarity to GB:AAU94302.1; match to protein family HMM PF01297

DNA sequence : 
ATGAAAATAAAAGCGTTTTTTACAACAATTTTTTTAAGCACAATCTTTTTGATCCCAGGTTTGGCTTTGAGTGCTAATAA
ATTTAAGGCTGTGACAACCTTTACCATTATTGCTGATATGGCGCGTAATGTGGCAGGTGACATTGCTGATGTTGAATCGA
TCACTAAACCAGGTGCTGAAATTCACGAATATCAACCTACACCACATGATCTTATGCGTGCGCAGGGAGCTAATCTTATA
TTGTGGAATGGATTAGATTTAGAACTTTGGTTTGAAAAGTTTTTTCAAAATATTGAAAATGTCCCAAGTGTTGTTGTTTC
AAAAGGTGTTAAACCTATTAAAATTGGCGAAGGGCCTTATAATGGTAAACCAAATCCTCATGCATGGATGTCACCGATTT
CAGCTCTAATTTACATTGATAATATTCGCGATGCTTTTGTAAAATATGATCCTAAAAATGCGGCTATTTATAAAGAGAAT
GCCGAAATCTATAAGCAGAAGATCCGCTTAAGTATTGATCCAATCAAAACTAAATTAAAAACCTTACCAAAAGGCAAGCG
CTGGCTTGTAACCAGTGAGGGTGCATTTAGCTATTTGGCGCGTGATTTTGGTTTGAAAGAACTTTATTTGTGGCCAATTA
ACGCTGATCAGCAGGGAACGCCGCAGCAGGTGAAACGTGTTATTGATATGGTTCGCAAATATAATATTCAAGCAGTTTTT
TCTGAAAGCACTATTTCTGATGCACCTGCTAAGCAGGTTGCCAGAGAAACAAAAGCTAAATATGGCGGTGTTCTTTATGT
CGATTCACTAAGTGAGGAAGATGGTGAAGTCCCTACCTATATTGATTTATTACGTGTTACGAGTGCGCGTATTGCTCATG
CTTTATCGGAAGGGTTTAAAGGTCAATGA

Protein sequence : 
MKIKAFFTTIFLSTIFLIPGLALSANKFKAVTTFTIIADMARNVAGDIADVESITKPGAEIHEYQPTPHDLMRAQGANLI
LWNGLDLELWFEKFFQNIENVPSVVVSKGVKPIKIGEGPYNGKPNPHAWMSPISALIYIDNIRDAFVKYDPKNAAIYKEN
AEIYKQKIRLSIDPIKTKLKTLPKGKRWLVTSEGAFSYLARDFGLKELYLWPINADQQGTPQQVKRVIDMVRKYNIQAVF
SESTISDAPAKQVARETKAKYGGVLYVDSLSEEDGEVPTYIDLLRVTSARIAHALSEGFKGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 5e-89 70
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 5e-89 70
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 4e-89 70
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-89 70
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 5e-89 70

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeA YP_989559.1 iron chelate ABC transporter, periplasmic iron chelate-binding protein BAC0349 Protein 2e-89 70
afeA YP_989559.1 iron chelate ABC transporter, periplasmic iron chelate-binding protein BAC0439 Protein 8e-82 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeA YP_989559.1 iron chelate ABC transporter, periplasmic iron chelate-binding protein VFG0525 Protein 2e-89 70