Gene Information

Name : Ajs_3445 (Ajs_3445)
Accession : YP_987635.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 3638504 - 3639832 bp
Length : 1329 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGACATCCTCCTCCTTCGCAAAGACCTCGCATCGGCCGTCGCACGGCTGGAAACCCGCAAGAAGCCCCAGGCCTT
CCTGAATGTGGAGGCGTTCCAGGCCCTGGAGTCCGAGCGCAAGACCATCCAGATGCGCACCGAGGAGTTGCAGTCGCAGC
GCAACCAGCTGTCCAAGCAGATCGGCATGCTCATGGGCAAGGGTGAGAAGGACGCCGCCGAGGCTGCGAAAGCCCAGGTG
GCCGCGATCAAGGCGGAACTGGACGGTTCTGCCACCCGGCTGGATCAGATCCAGGGCGAACTGCAAACGATGCTGGCCGC
CGTCCCGAATCTGCCGCACGAGAGCGTGCCCGTGGGCTCGGACGAGAGCGCCAATGTGGAGGTGCGCCGCTGGAGCCCCG
ATGGCCAACAGCCGCGCAGCCTGGGCTTCACCCCCAAGGACCATGTGGACCTGGGCGAGCCGCTGGGCCTGGACTTCGAC
ATGGGCGTGAAGCTCTCGGGATCGCGCTTCACGGTGATGAAGGGGGGCATCGCGCGCCTGCACCGGGCCCTGGCGCAGTT
CATGCTGGATGTGCAGACCCAGGAGCACGGCTACACCGAGTGCTACGTGCCCTACGTCGTCAATGCGGACTCGCTCAAGG
GCACGGGCCAATTGCCCAAGTTCGAGGGCGACCTCTTCGCGGCCCAGAAGGGCGGTCAGGATGCCGAGCCCGTACCCGAC
AACGCGCAGCTGTACCTCATCCCCACGAGCGAGGTGCCCCTGACCAACTTCGTGCGCGACGAAGTCTTGGCCGAGGCCCA
GCTGCCGCTCAAGCTCACGGCCCATACGCCCTGCTTTCGGTCGGAAGCCGGCAGCTACGGCCGGGACACGCGCGGCATGA
TCCGCCAGCACCAGTTCGACAAGGTCGAGATGGTGCAGATCGTGCATCCCGACAAGAGCTACGAGGCGCTGGAGGAAATG
ACCCGCCATGCTGAGGCTGTGCTGCAGAAGCTGGGCCTGCCCTACCGCGTGATGAGCCTGTGTACGGGCGACATGGGCTT
TGGCGCCGCCAAGACCTACGACCTGGAAGTGTGGCTGCCCGCCCAGAACACCTACCGTGAGATCAGTTCGGTGAGCAACT
GCGAAGCCTTCCAGGCCCGCCGCCTGCAGGCGCGCTTCAAGAACGCGCAGGGCAAGAACGAGCTGGTGCACACCCTCAAC
GGGTCTGGCCTGGCCGTGGGCCGCACGCTGGTGGCGGTGCTGGAGAATTACCAGAACGAGGACGGCAGCGTGACCATTCC
TGAGGTGCTCCGCCCCTACATGGGCGGTCAAGCCACGCTGTCGGTCTGA

Protein sequence :
MLDILLLRKDLASAVARLETRKKPQAFLNVEAFQALESERKTIQMRTEELQSQRNQLSKQIGMLMGKGEKDAAEAAKAQV
AAIKAELDGSATRLDQIQGELQTMLAAVPNLPHESVPVGSDESANVEVRRWSPDGQQPRSLGFTPKDHVDLGEPLGLDFD
MGVKLSGSRFTVMKGGIARLHRALAQFMLDVQTQEHGYTECYVPYVVNADSLKGTGQLPKFEGDLFAAQKGGQDAEPVPD
NAQLYLIPTSEVPLTNFVRDEVLAEAQLPLKLTAHTPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVHPDKSYEALEEM
TRHAEAVLQKLGLPYRVMSLCTGDMGFGAAKTYDLEVWLPAQNTYREISSVSNCEAFQARRLQARFKNAQGKNELVHTLN
GSGLAVGRTLVAVLENYQNEDGSVTIPEVLRPYMGGQATLSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-98 53