Gene Information

Name : guaA (Ajs_2547)
Accession : YP_986781.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2711086 - 2712702 bp
Length : 1617 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAACACGACAAGATCCTCATCCTCGACTTCGGCTCCCAGGTCACCCAACTCATCGCGCGCCGCGTGCGCGAGACGCA
TGTCTACTGCGAGGTCCACCCCTGCGACGTGAGCAGCGACTGGGTGCGCCAGTTCGCCGCAGACGGCAAGCTCAAGGGTG
TGATCCTGTCGGGCAGCCACGCCAGCGTCTACGAAGTGGACGACCGCGCCCCTGACGCCGTGTTCGAGTTGGGCGTGCCC
GTGCTGGGTATCTGCTACGGCATGCAGACCATGGCCGCGCAACTGGGCGGCAAGGTCGAGGGCTCGCACAGTCGCGAGTT
CGGCTATGCCGAAGTCCGCGCCCATGGCCATACCGCGCTGCTCAAGGGCATCGAGGATTTCTCCACGCCCGAGGGCCACG
GCATGCTGAAGGTGTGGATGAGCCACGGCGACAAGGTCACAGAGCTGCCACCCGGTTTCAAGCTGATGTGCTCCACCGGC
AGCTGCCCCATCGCCGGCATGGCGGACGAAACGCGGCGCTTCTACGCCGTGCAATTCCACCCCGAGGTCACGCACACGGT
GCAGGGCGCGGCGCTGCTCAACCGCTTCGTGCGCGAGATCTGTGGCGCCCAGGCGGACTGGATCATGCGCGACCACATCG
AGGAAGCCGTGCAGAAGATCCGCGAGCAGGTGGGCGACGAGGAAGTGATCCTGGGCCTGTCTGGCGGTGTGGATTCGTCG
GTGGCTGCGGCCCTGATCCACCGTGCGATTGGCGACCAGCTTACCTGCGTGTTCGTGGACCACGGCCTGCTGCGCCTCAA
CGAAGGCGATATGGTCATGGACATGTTCGCAGGCAAGCTGCACGCGAAGGTGGTGCGCGTGGATGCCTCGGACCTGTTCC
TGGGTGAGCTGGCCGGTGTGTCCGAGCCCGAGCAAAAGCGCAAGATCATCGGCCGCCTGTTCGTGGACGTGTTCAAGGCC
GAAGCCGAAAAGCTCAAGGCCAGCGGCCAGGGCCACAAGGGCGCGACCTTCCTGGCGCAAGGCACCATCTACCCCGACGT
GATCGAGTCCGGCGGTGCCAAGAGCAAGAAGGCCGTCACCATCAAGAGCCACCACAACGTGGGCGGGCTGCCCGAGCAAC
TCGGCCTCAAACTGCTGGAGCCGCTGCGCGACCTGTTCAAGGACGAGGTGCGTGAGCTCGGCGTGGCCCTGGGACTGCCG
CGCGAAATGGTCTACCGCCATCCGTTCCCCGGCCCGGGCCTGGGCGTGCGCATTCTGGGCGAGGTGAAGAAGGAATACGC
CGACCTGCTGCGCCGCGCCGATGCCATCTTCATCGAAGAGCTGCGCAACTTCACCGACGAAGCCACGGGCAAGACCTGGT
ACGACCTCACCAGCCAGGCCTTCACCGTGTTCCTGCCGGTCAAGAGCGTGGGCGTGATGGGCGATGGCCGCACCTACGAC
TATGTGGTGGCACTGCGCGCGGTGCAGACCAGCGACTTCATGACAGCCGACTGGGCGGAGTTGCCCTACGCGCTGTTGAA
GAAGGTCTCCAGCCGCATCATCAATGAGGTGCGCGGCATCAACCGCGTGACCTACGACGTGTCGAGCAAGCCGCCTGCCA
CCATCGAGTGGGAGTGA

Protein sequence :
MQHDKILILDFGSQVTQLIARRVRETHVYCEVHPCDVSSDWVRQFAADGKLKGVILSGSHASVYEVDDRAPDAVFELGVP
VLGICYGMQTMAAQLGGKVEGSHSREFGYAEVRAHGHTALLKGIEDFSTPEGHGMLKVWMSHGDKVTELPPGFKLMCSTG
SCPIAGMADETRRFYAVQFHPEVTHTVQGAALLNRFVREICGAQADWIMRDHIEEAVQKIREQVGDEEVILGLSGGVDSS
VAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMDMFAGKLHAKVVRVDASDLFLGELAGVSEPEQKRKIIGRLFVDVFKA
EAEKLKASGQGHKGATFLAQGTIYPDVIESGGAKSKKAVTIKSHHNVGGLPEQLGLKLLEPLRDLFKDEVRELGVALGLP
REMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRNFTDEATGKTWYDLTSQAFTVFLPVKSVGVMGDGRTYD
YVVALRAVQTSDFMTADWAELPYALLKKVSSRIINEVRGINRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-124 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-124 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-124 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-111 48