Gene Information

Name : Ajs_1461 (Ajs_1461)
Accession : YP_985746.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Virulence
Product : two component heavy metal response transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1521370 - 1522053 bp
Length : 684 bp
Strand : -
Note : TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: tbd:Tbd_1749 two component heavy metal response transcriptional regulator, winged helix family

DNA sequence : 
ATGAAGATATTGATCGTCGAAGATGAACCTAAAACCGGCGAATACCTTCGCCAGGGATTGAGCGAGGCCGGATTTGTGGC
CGACCTGGCGCAAAACGGTAGTGATGGCCTGCACCTGGCACTCCAAGGTGAATACGACCTCGTGATCCTGGATGTCATGC
TGCCCGGACTGGATGGCTGGCAGGTGCTGCAGTCGCTGCGCAATCGCGGATTGCAGATGCCTGTGTTGTTCCTCACGGCG
CGGGACCAGGTGGAAGATCGGGTCAAAGGGTTGGAATTGGGCGCTGACGACTATCTTGTCAAGCCCTTTTCATTCGCCGA
GTTGCTGGCCCGTGTACGGACAATCTTGCGCCGGGGCCGAGGAGGCACCGAAACCAACACATTGCGCGTGGCTGACCTGG
AACTTGATCTGCTGCGCCGACGGGTCTCGCGGGGTGGCCGTCGCATTGACCTGACAGCCAAAGAATTTGGTTTGCTGGAG
TTGCTGTTGCGCAGGCATGGAGAAGTGCTTCCTCGCTCGCTGATTGCCTCCCAGGTGTGGGACATGAACTTCGACAGCGA
CACCAACGTGATCGAAGTGGCGATGCGCCGCTTGCGCCTGAAGATTGACGAAGGCCAGGACGTCAAGTTGATCCAGACCG
TGCGGGGCATGGGCTACGTGCTGGAAGCACCGGAGAACGCTTGA

Protein sequence : 
MKILIVEDEPKTGEYLRQGLSEAGFVADLAQNGSDGLHLALQGEYDLVILDVMLPGLDGWQVLQSLRNRGLQMPVLFLTA
RDQVEDRVKGLELGADDYLVKPFSFAELLARVRTILRRGRGGTETNTLRVADLELDLLRRRVSRGGRRIDLTAKEFGLLE
LLLRRHGEVLPRSLIASQVWDMNFDSDTNVIEVAMRRLRLKIDEGQDVKLIQTVRGMGYVLEAPENA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 8e-51 62
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 8e-50 61

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0638 Protein 2e-59 70
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0083 Protein 9e-58 68
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0197 Protein 1e-58 68
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0111 Protein 9e-58 66
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0308 Protein 7e-55 66
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0347 Protein 3e-52 64
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0125 Protein 3e-56 64
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator BAC0487 Protein 2e-25 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator VFG0596 Protein 3e-51 62
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator VFG1390 Protein 4e-34 47
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator VFG1386 Protein 1e-31 45
Ajs_1461 YP_985746.1 two component heavy metal response transcriptional regulator VFG1389 Protein 7e-28 45