Gene Information

Name : Ajs_1445 (Ajs_1445)
Accession : YP_985731.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1505436 - 1507448 bp
Length : 2013 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGCTGTTTCTGTGCGAGAAGCCCTCCCAGGGCAAAGACATCGGCCGGATTCTCGGCGCCACGCAGCGCGGTGAAGG
CTGCCTCAACGGCTCCGGCGTCACGGTCACCTGGTGCATCGGCCATCTCGTCGAAGCGGCAGCACCCGAGGTCTATGACG
CGGCGCTCAAGCGCTGGTCGTTGGAGCAGTTGCCCATCATCCCTCAGCAGTGGCGGGTCGAGGTCAAACCGCAGACCGCC
ACGCAATTCAAGGTCGTAAAAACGCTTCTGGCGAAGGCGACCCATCTCGTCATTGCCACCGATGCCGACCGCGAGGGTGA
ACTGATCGCCCGCGAGATCATCGACCTGTGCGGATACCGCGGCCCCATAGCACGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCCATCCGCACCGCGCTCGCCAAGCTGCGGCCCTCGGCCGAGACGCTGCCGATGTATTACTCGGCGCTGGCGCGCTCG
CGCGCCGACTGGCTCGTCGGCATGAACCTCAGCCGGCTGTTCACCGTGCTCGGGCGGCAGGCCGGCTACGACGGCGTGCT
GTCGGTCGGGCGTGTACAGACCCCGACGCTCAAACTCGTGGTGGACCGCGACCGAGAGATCGCGGCCTTCGTGTCCGTGC
CGTACTGGGCCATCGACGTGTCCCTGTCCGCAGGCGGTCAGACGTTCACCGCGCAGTGGGTGGCACCCGACGCCAGCACC
GACGACGCCGGCCGCTGCCTGCAGCAGCCCGTCGCACAGCAGGCCGCGCAACAGATCCGCGCCGCGGGCAGTGCCCAGGT
GGTGTCGGTCGAGACCGAGCGCGTGCGCGAAGGCCCGCCGCTGCTGTTCGACCTGGGCACCTTGCAGGAAGTCTGTTCCA
AGCAGCTTGGGCTGGACGTGCAGGAAACCTTGGAGATCGCCCAGGCTCTGTACGAGACGCACAAGGCCACGACGTACCCG
CGCTCGGATTCGGGCTACCTGCCCGAAAGCATGTTCGCCGAGGTGCCCACGGTCCTGGACAGCCTGCTCAAGACCGATCC
CACGCTGGCCCCGATCATGGGCCAGCTCGACCGCGCCCAGCGCTCGCGCGCCTGGAACGACAGCAAGGTGACGGCGCACC
ACGGCATCATCCCGACGCTCGAACCCGCGAACCTCTCCGCCATGAGCGAGAAGGAGCAGGCGGTGTACCGGCTGATCCGG
GCGCATTACCTGGCCCAGTTCCTCCCGCACCACGAGTTCGACCGCACGATCGCCGAGCTGTCCTGCGGCCAGCAGAAGCT
GGTGGCCACCGGAAAGCAGGTGGCCGCCCAGGGTTGGCACCTGGTGCTGGCCGAGCCGCAAGCGGACGAGGACGGGGAAA
CCACCGCGCGCAGCCAGGTACTCCCCGCGCTGCGCGAGGGCCTGGCATGCCAAGTGGCCGAGGCCGAAGTCAAGGCGCTC
AAGACGCTGCCTCCGAAGCCCTACACGCAGGGCGAACTGGTCAAGTCGATGAAAGGCGTGGCGCGCTTCGTGACCGACCC
GCGCCTGAAGCAGAAGTTGAAGGACACGACGGGCATTGGCACCGAAGCCACGCGCGCCAACATCATCACCGGCCTGCTGA
CGCGGGGCTATCTCGTGAAGAAAGGACGCTCCATTCGCGCATCGGATGCGGCGCTCACGCTGATAGACGCCGTGCCCGCG
GCGATTGCCGACCCCGGAACCACCGCCGTGTGGGAGCAGGCGCTGGACATGATCGAGGCCGGACAACTCACCCTGGATGT
GTTCATCGGCAAGCAGGCCGCATGGATTTCGCAACTGATCGTGCAGTACGGCAGCACCTCGCTGTCCATCAAGGTTCCCC
AGGGTCCCGCTTGCCCGCAGTGCGGCGCACCGACGCGCCAGCGCACCGGCAAGACCGGCCCCTTCTGGTCGTGCAGTCGC
TACCCCGACTGCAAAGGCACGCTGCCGGTCGAAACCGGCACGTCCAAGCGTGGTGCCTCGCGCCCACGCAAGAGCGGCCG
CAAAGGCTCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPQTA
TQFKVVKTLLAKATHLVIATDADREGELIAREIIDLCGYRGPIARLWLSALNDASIRTALAKLRPSAETLPMYYSALARS
RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDAST
DDAGRCLQQPVAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP
RSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRAQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIR
AHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKAL
KTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAALTLIDAVPA
AIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSR
YPDCKGTLPVETGTSKRGASRPRKSGRKGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 89
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 75
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 62
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-169 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-169 51
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-169 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-169 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 2e-167 50