Gene Information

Name : Ajs_1335 (Ajs_1335)
Accession : YP_985630.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1402423 - 1404684 bp
Length : 2262 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2

DNA sequence :
ATGGCCCACGATCACCCCCACGACATCAAGCCGGATCCGGCCGGCGCACTGCAACCGGCTGGCTGCGGCGCCTGCTGCGG
CGCTTCCGACCACGCACCTGCTGCCTCTGCCTCGGTCCCCCTGGGTGGTGGCCAGCGCTTCCGCATTCCGGCGATGGACT
GCGCCAGCGAGGAGTCCGAGATCCGTCGCGCTGTCGAGGGCATCCCCGGCGTCCTGGGGCTACGCTTCCAGCTGGGCGAG
CGCAGCCTGCGCATAGCCGGCGAGCCGCAGGCAGCGCTGGCGGCAGTGGAAGCCATCCGGAACTCCGGATTCGAGGTTCA
CGCCTGGCCCGACGCGACGGAGTCGTCCAACGCCGGTGATGGATCGGATCACGGCCACGACGCAGCAACCGGGTCCGGCC
TGCCCCGCCTGCTGGCTGCCCTCGCTCTTGCGACGGCTGCCGAGGCCCTGTCCTTCCTGGCACCGGACGCGCCCTGGTCC
AAGTGGGCTGGCCTGGCCGTTGCAGCCGCGGCCATCGGGCTGGCCGGCTTCGGCACGTTCCGCAAGGGCCTGTCCGCCCT
GCGGCACGGCCGCCTGAACATCAATGCACTGATGTCAGTGGCGGTCGCGGGAGCCTTCGTGATCGGCCAGTGGCCTGAGG
CGGCCATGGTCATGGCGCTGTACGCGATCGCCGAACTGATCGAGGCGCGGGCCGTCGACCGCGCGCGCAATGCAATCAGC
GGCCTGCTGGCGCTGTCGCCCGACACCGCCGACCTGCGGCAGCCCGACGGCACCTGGAGATCCGCGCCCGTCGGCAGCGT
ACCTATCGGCGCCACGGTCCGGGTCAAGCCGGGCGAACGCGTGGCCATGGATGCCATCGTCACCGACGGCAGCACCGCCG
TGGACCAGGCGCCCGTCACCGGCGAGAGCCTGCCGGTCGACAAGGGGCCGGGCGATGCGGTCTTCGCCGGCACCATCAAC
CAGACCGGCACCATCGAGTGCCGTGTCACCGCCGCGGCGTCGCAATCGACGCTGGCCCGCATCATCCACGCGGTCGAACA
GGCCCAGGGCAGCCGTGCGCCCACGCAGCGCTTCGTCGACCGGTTCGCGGCCGTGTACACACCGGCGGTGTTCGTGCTGG
CACTGGCCGTTGCCATCGCCGGCCCGTGGCTCTTCGGCTGGACGGTGCTGGCCGCGGTCTACAAGGCGCTGGTGCTGCTG
GTCATCGCCTGCCCGTGCGCCCTCGTGATCTCGACGCCCGTCACCGTCGTCAGCGGGCTGGCGTCGGCGGCCAGGCGGGG
CATTCTGATCAAGGGCGGCGTCCACCTCGAACAGGCGCGCCTGCTCAAGGCGGTCGCGCTCGACAAGACCGGCACCATCA
CCGAAGGCAGGCCGCGCCTCGTCGAGTGGGAGATGCTGTCCACCAGCCTGCCCAAGCCGCAGGCCGAACACATCGCAGCC
GCGCTGGCGGCGCACTCGGACCACCCGGTGTCGCGCGCCATCGCCGCGGGGCTGACGCCGAACAGCGTCGAGGCCCGCAA
CTTTGCCGCGCTGTCCGGGCGCGGCATCGAAGCCGACATCGGCGGCCAGCGCTACGTGCTGGGCAACCACCGCCTGATCG
AGGAGCGCGGCCAGTGCTCCGCCGAGATCGAGGCCGTGCTCCACCGTCACGAGGAAGCGGGCCGCACGGTCAGCCTGCTG
GCCACCGCGTCCGGGGTGCTGGCGCTCTTCGCGGTGGCCGACACGATCAAGCCCTCGTCGGCCGCCGCCATCGGCGAGCT
GAAGGCGATGGGCATCACGCCGGTGATGCTGACCGGTGACAACCAGGCCACCGCCGAGGCCATCGGCCGCGAGGCCGGTA
TGACGGACATCCGCGGCAACCTGCTGCCCGAGGACAAGCTCGCCGCGATCCAGGCCATGCAGAAGCAGTATGGGGCGACG
GCGATGACCGGCGACGGCATCAACGACGCACCCGCGCTGGCGCAGGCCGACATCGGCGTGGCGATGGGCGCTGCCGGCAC
CGACATCGCGATGGAAGCGGCCGACGTGGTGGTGATGAACGACGATCTGCGGCGCATTGCCGAGACGGTGCGCCTGTCGC
AACGCACGCACGCCGTGCTGTGGCAAAACATCGCGCTGGCTCTCGGCATCAAGGCCGTCTTCCTGGTGCTCGCGCTGTTC
GACAACGCCAGCATGTGGATGGCCGTGTTCGCCGACATGGGGGCCAGCCTGTTGGTGGTCTTCAACGGCCTGCGCCTGTT
GCGAAACCCCGAACGAAGCTGA

Protein sequence :
MAHDHPHDIKPDPAGALQPAGCGACCGASDHAPAASASVPLGGGQRFRIPAMDCASEESEIRRAVEGIPGVLGLRFQLGE
RSLRIAGEPQAALAAVEAIRNSGFEVHAWPDATESSNAGDGSDHGHDAATGSGLPRLLAALALATAAEALSFLAPDAPWS
KWAGLAVAAAAIGLAGFGTFRKGLSALRHGRLNINALMSVAVAGAFVIGQWPEAAMVMALYAIAELIEARAVDRARNAIS
GLLALSPDTADLRQPDGTWRSAPVGSVPIGATVRVKPGERVAMDAIVTDGSTAVDQAPVTGESLPVDKGPGDAVFAGTIN
QTGTIECRVTAAASQSTLARIIHAVEQAQGSRAPTQRFVDRFAAVYTPAVFVLALAVAIAGPWLFGWTVLAAVYKALVLL
VIACPCALVISTPVTVVSGLASAARRGILIKGGVHLEQARLLKAVALDKTGTITEGRPRLVEWEMLSTSLPKPQAEHIAA
ALAAHSDHPVSRAIAAGLTPNSVEARNFAALSGRGIEADIGGQRYVLGNHRLIEERGQCSAEIEAVLHRHEEAGRTVSLL
ATASGVLALFAVADTIKPSSAAAIGELKAMGITPVMLTGDNQATAEAIGREAGMTDIRGNLLPEDKLAAIQAMQKQYGAT
AMTGDGINDAPALAQADIGVAMGAAGTDIAMEAADVVVMNDDLRRIAETVRLSQRTHAVLWQNIALALGIKAVFLVLALF
DNASMWMAVFADMGASLLVVFNGLRLLRNPERS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-109 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-109 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ajs_1335 YP_985630.1 heavy metal translocating P-type ATPase BAC0298 Protein 3e-140 61