Gene Information

Name : Ajs_1298 (Ajs_1298)
Accession : YP_985596.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1368196 - 1369884 bp
Length : 1689 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: mca:MCA134

DNA sequence :
ATGGCCGAGGCGATCACCCTCCACATCGAAGGCATGACCTGCACGTCGTGCGCCGAGCACGTCCAGCAGGCTTTGACGAA
CGTGCCCGGCGTGCGCGCGGCCTCGGTGTCCTATCCGCAGCGGCAGGCCGAAATCGAGGCGGATGCAGGCGTGAGCGTGG
CCCCGCTGGTTGCCGCAGTGGCCACGCTCGGCTATCGCGCACGGCTTACCGACACGCCGAACAAGCCTGCCGGCCTGCTA
GACAAGGCGCTGGGCTGGCTCGGTGGCGAAACGAAGCATGTTGGCGGTGAACAAGCGCTGCACGTGGCTGTGATAGGCAG
CGGCGGCGCGGCGATGGCGGCTGCCTTGAAGGCCGTGGAGCAAGGCGCCCGCGTCACGCTGATCGAGCGCGGCACCATCG
GCGGCACCTGCGTCAATGTCGGCTGCGTGCCGTCCAAGATCATGATCCGCGCCGCGCACATCGTCCACCTGCGCCGCGAA
AGCCCGTTCGATGCTGGCCTGCCGGCCGCAGCGCCCGCTGTACTGCGCGAGCGGCTGCTGGCCCAGCAACAAGGCCGCGT
CGAGGAGCTGCGCCATGCCAAGTACGAAGGCATCCTGGCAAGCACTCCGGCCATCACCGTGCTGCGCGGCGAGGCCCGGT
TCAGGGACACGCGCACGCTGACCGTGGCGACCGCTGACGGCGGCACGCACGAGGTGAACTTCGACCGCTGCCTGATTGCC
ACCGGCGCGAGCCCGGCGCTTCCGCCAATCCCGGGCCTTGCGGACACACCCCACTGGACCTCCACCGAGGCGCTGGAAAG
CAGCTCGCTCCCCGAGCGGCTGGCCGTGATTGGTTCCTCCGTGGTGGCGGTCGAGTTGGCGCAAGCCTTCGCCCGGCTGG
GCAGCCAGGTCACGATCCTGGCGCGCAGCACGCTGTTCTTCCGAGAAGACCCGGCCATCGGGGAAGCCGTAACAGACGCC
TTCCGCGCCGAGGGCATCGAGGTGCTGGACCACACCCAGGCGAGCCACGTTGCCTATGCGGGCGGGGAATTCGTGCTCAC
CACCGGGCAGGGGGAAGTGCGCGCCGACAAGCTGCTGGTCGCCACCGGTCGCGCGCCGAACACGCGCAGCCTGAACCTTG
AAGCGGCAGGCGTCGAAGTCAATGCGCAGGGAGCCATCGTCATCGACCGCGCCATGCGCACGAGCGCACCGCACATCTTT
GCTGCCGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCGGCGGCCGGCACGCGCGCCGCGATCAACATGAC
CGGCGGCGACGCGGCGCTGGACCTGACGGCGATGCCGGCGGTGGTGTTCACCGATCCGCAGGTGGCGACCGTGGGCTACA
GCGAGGCGGAAGCGCACCACGACGGCATCGAGACCGACAGCCGGCTGCTGACGCTCGACAACGTGCCGAGGGCGCTCGCC
AACTTCGACACGCGCGGCTTCATCAAGCTGGTGGCGGAAGCTGGCTCAGGGCGGCTGATCGGCGTACAGGCGGTCGCGCC
GGAAGCGGGCGAACTGATCCAGACGGCCGCGCTGGCGATCCGCCACCGGATGACCGTGCAGGAGCTGGCCGACCAGTTGT
TCCCCTACCTGACCATGGTCGAGGGACTGAAGCTCGCGGCGCAGACCTTCAACAAGGACGTGAAGCAACTGTCCTGTTGC
GCCGGATGA

Protein sequence :
MAEAITLHIEGMTCTSCAEHVQQALTNVPGVRAASVSYPQRQAEIEADAGVSVAPLVAAVATLGYRARLTDTPNKPAGLL
DKALGWLGGETKHVGGEQALHVAVIGSGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIVHLRRE
SPFDAGLPAAAPAVLRERLLAQQQGRVEELRHAKYEGILASTPAITVLRGEARFRDTRTLTVATADGGTHEVNFDRCLIA
TGASPALPPIPGLADTPHWTSTEALESSSLPERLAVIGSSVVAVELAQAFARLGSQVTILARSTLFFREDPAIGEAVTDA
FRAEGIEVLDHTQASHVAYAGGEFVLTTGQGEVRADKLLVATGRAPNTRSLNLEAAGVEVNAQGAIVIDRAMRTSAPHIF
AAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRLLTLDNVPRALA
NFDTRGFIKLVAEAGSGRLIGVQAVAPEAGELIQTAALAIRHRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCC
AG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 100
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 80
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 80
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 80
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 80
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 80
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 79
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 79
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 77
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-87 41
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-87 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ajs_1298 YP_985596.1 putative mercuric reductase BAC0653 Protein 0.0 82
Ajs_1298 YP_985596.1 putative mercuric reductase BAC0652 Protein 0.0 79
Ajs_1298 YP_985596.1 putative mercuric reductase BAC0650 Protein 9e-180 70
Ajs_1298 YP_985596.1 putative mercuric reductase BAC0224 Protein 2e-85 42
Ajs_1298 YP_985596.1 putative mercuric reductase BAC0651 Protein 1e-87 41