Gene Information

Name : Ajs_1242 (Ajs_1242)
Accession : YP_985543.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1319914 - 1322313 bp
Length : 2400 bp
Strand : +
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: rme:Rm

DNA sequence :
ATGAGTGAATGTGGCTCCAAGGGATGTGGCTGCTCTACCGTTGTGGTGCCCAACCCGAAACCGAACATCGTCGAAGCAGC
GTTGCCGCAGGTGCGCTACCGCATCGAGAACATGGATTGCCCGACCGAGGAAGCGTTGATTCGCGACAAACTCGGAAAGG
TGCAGGGCGTGAGCAGCCTTGAATTCAATCTGGTGCAGAGAACACTGGGAGTCAGCCATCAGCTTGCCTCGTTGCGCCCT
ATCGAAGACGCGTTATCGGCCATCGGGATGCGAGCGGTTCGGATGGATGAGAAGGCAGCCCAGCAAAGTACCTGGTTATC
CATCCAGCAGATGGACTGCCCCACCGAGGAGGCATTGATCCGCGGCAAGCTTGCCGGCGTGCCAGGCGTTGCGAATCTTG
AATTCAACCTCGTCCAGCGCAGGCTGCACGTCGCACATACACCCGACGCACTTCCCAATGTGCTTGCAGCCCTGAAATCG
CTCGGCTTCGACGCCGAGGTGCGCACTTCTTCGGCCCCTTCGGCAGCCGAGGCGCAAGCGCCTGCACGCACAAACTGGTG
GCCGCTGGCAGTGTCAGGCGTCACCGCAACGCTGGCCGAGGTTGTGTACTGGCTCAACGGCGGCAACCACTGGGTCGTGG
TCGCGCTGGCCGTGGTGGCCATCCTCACTGGCGGCCTCACGACTTACAAGAAGGGCTGGATTGCGCTCAGGAACCGCAAC
CTGAACATGAATGCGTTGATGTCCATTGCGGTCACTGGGGCCATGCTCATAGGCCATTGGCCCGAGGCGGCTATGGTGAT
GGTGCTGTTCGCACTAGCCGAGGTGATCGAGGCCAAGTCCTTGGATCGGGCTCGCAATGCCATCCGTGGCTTGATGGACC
TCGCGCCGGATACCGCATTGGTTCAACAAGCGGACGGCAGTTGGGCTGCGGTGGACGCCAACGCCGTGCCCGTGGGCAGC
CGTGTTCGCGTCAAACCTGGTGAGCGCATTGCCCTCGATGGGCTGATCGTCGAAGGCCGCTCCTCCGTCAATCAGGCGCC
GATCACTGGTGAGAGCCTTCCGGTAGACAAGGCTGAGGGCGATTCCGTGTTTGCAGGCACGATCAATGGGGAGGGTTCGT
TTGAATTCCGCGTCACCGCTGCCGCCAGCGCATCGACATTGGCCCGCATCATTCATGCCGTTGAAGCGGCTCAGGGAAGC
CGCGCGCCGACGCAGCGTTTCGTCGATCAGTTTGCGCGGCTGTATACGCCTATCGTATTTGCGGTAGCCCTTGCCGTGGC
GCTTGTGCCTCCGCTGGTATTCGGCGTGCCGTGGCTGGACTGGATCTACAAGGCGCTGGTTCTATTGGTCATCGCTTGTC
CTTGTGCTCTGGTGATCTCCACGCCGGTGAGCATTGTGAGCGGTCTGGCTGCTGCCGCACGGCACGGCATCCTGATCAAG
GGTGGCGTCTATCTGGAAGAGGGGCACAAGCTCAAATGGCTGGCCCTGGACAAAACGGGCACGATCACACACGGCAAGCC
AGCGCAGACTGATTTCGCTGCATGGGGCAACGCCGATCCTGATGCGTCCAGATTGCTGGCCGCCAGCCTCGCAGCCCGTT
CAGACCACCCAGTGTCCTTGGCAGTGGCCCGTGCAGCCGTCAACGATGGGTTGACACCGCGTGATGTAGCCGATTTCGCA
GCGCTGCCTGGGCGCGGGGTTCGTGGCGACATCAACGGGCAGATCTATCACCTGGGTAACCACCGCCTGGTCGAGGAACT
GGGCATGTGTTCGCCAGATCTGGAGTCCAGGGTGTCTGCGCTTGAAGCCGAGGGCAAAACCGTAGTGATGTTGACGGGAC
AGGAAGGAGTGCGGGCGCTCTTCGCAGTGGCTGACACGGTGAAGGACAGCAGCCGCCAGGCCATTGCCGAACTGCACCGA
CTGGGCATCAAAGCCATTATGTTGACCGGTGACAACCCGCACACTGCCGCTGCCATTGCCAGTCAGGTCGGCATTGACCG
CAGTCGTGGCAATCTGCTGCCCGAAGACAAACTGCATGAAGTGGAGCGACTGTCGGCGGACGGGAAAACTGGCATGGTGG
GCGATGGCATCAACGATGCCCCGGCGCTCGCGCGTGCGGACATCGGCTTTGCAATGGGGGCGGCGGGAACCGATACGGCC
ATCGAAACCGCCGACGTTGCGTTGATGGATGACGACCTGCGCAAGCTGCCGACATTCGTGCGACTGTCCAGTGCAACAGC
TAGCGTTTTGAAGCAGAACATCGCCCTCGCGCTGGGCATCAAGGCGGTGTTCCTGATTCTGACTTTCACCGGGCAAGCCA
CGATGTGGATGGCGGTGTTTGCCGACATGGGGGCCAGTCTGCTGGTGGTCGGCAACGGGTTGAGGCTGTTGCGCCGATGA

Protein sequence :
MSECGSKGCGCSTVVVPNPKPNIVEAALPQVRYRIENMDCPTEEALIRDKLGKVQGVSSLEFNLVQRTLGVSHQLASLRP
IEDALSAIGMRAVRMDEKAAQQSTWLSIQQMDCPTEEALIRGKLAGVPGVANLEFNLVQRRLHVAHTPDALPNVLAALKS
LGFDAEVRTSSAPSAAEAQAPARTNWWPLAVSGVTATLAEVVYWLNGGNHWVVVALAVVAILTGGLTTYKKGWIALRNRN
LNMNALMSIAVTGAMLIGHWPEAAMVMVLFALAEVIEAKSLDRARNAIRGLMDLAPDTALVQQADGSWAAVDANAVPVGS
RVRVKPGERIALDGLIVEGRSSVNQAPITGESLPVDKAEGDSVFAGTINGEGSFEFRVTAAASASTLARIIHAVEAAQGS
RAPTQRFVDQFARLYTPIVFAVALAVALVPPLVFGVPWLDWIYKALVLLVIACPCALVISTPVSIVSGLAAAARHGILIK
GGVYLEEGHKLKWLALDKTGTITHGKPAQTDFAAWGNADPDASRLLAASLAARSDHPVSLAVARAAVNDGLTPRDVADFA
ALPGRGVRGDINGQIYHLGNHRLVEELGMCSPDLESRVSALEAEGKTVVMLTGQEGVRALFAVADTVKDSSRQAIAELHR
LGIKAIMLTGDNPHTAAAIASQVGIDRSRGNLLPEDKLHEVERLSADGKTGMVGDGINDAPALARADIGFAMGAAGTDTA
IETADVALMDDDLRKLPTFVRLSSATASVLKQNIALALGIKAVFLILTFTGQATMWMAVFADMGASLLVVGNGLRLLRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 69
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-117 48
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-117 48
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 9e-115 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ajs_1242 YP_985543.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 86