Gene Information

Name : thyA (Ajs_1197)
Accession : YP_985505.1
Strain : Acidovorax sp. JS42
Genome accession: NC_008782
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1267599 - 1268432 bp
Length : 834 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACCCCACGCCCCATCCGCCACCAATACGAAGACCTGATGCGCCATGTGTTCGAACATGGCACGGCCAAGGGCGACCG
CACGGGCACGGGCACCAAGAGCGTGTTCGGCCACCAGATGCGCTTTGACCTCTCCGAGGGCTTTCCGCTGGTGACCACCA
AGAAGGTGCACCTCAAGAGCATCATCCTGGAGCTGCTGTGGTTCCTGCGCGGCGACAGCAACGTGCGCTGGCTGCAGGAG
CGCGGCTGCACCATCTGGGACGAGTGGGCGCGCGACGACGGCAGCCTGGGCCCCGTGTACGGCGTGCAGTGGCGCAGCTG
GCCCACGCCGGACGGCGGCCACATCGACCAGATCCAGCAAGTGATCGACACCCTCAAGACCCACCCCGACAGCCGCCGCA
TCATCGTGAGCGCCTGGAACGTGGCCGAGCTGGACCGGATGGCGCTCATGCCCTGCCACGCATTCTTCCAGTTCTACGTG
GCGCCATCCCAGGTGGCTGGTGAGCCGGGCAAACTGAGCTGCCAGCTCTACCAGCGCAGCGCAGACATCTTCCTGGGCGT
GCCGTTCAACATCGCGTCGTACGCGCTGCTCACGCACATGGTGGCGCAGCAGTGCGACCTGCAAGTGGGTGACTTCATCT
GGACCGGCGGCGACTGCCATATCTACAGCAACCATTTCGAGCAGGTGCGGACCCAACTGGCGCGCCAGCCCTATGCCTAC
CCGACGCTGCAGATCAAGCGCCGGCCCGCATCCATCTTTGATTACGCCTACGAAGACTTCGAAGTGGTGGGCTACGAACA
CCACCCCGCCATCAAGGCGCCGGTGGCGGTGTAG

Protein sequence :
MTPRPIRHQYEDLMRHVFEHGTAKGDRTGTGTKSVFGHQMRFDLSEGFPLVTTKKVHLKSIILELLWFLRGDSNVRWLQE
RGCTIWDEWARDDGSLGPVYGVQWRSWPTPDGGHIDQIQQVIDTLKTHPDSRRIIVSAWNVAELDRMALMPCHAFFQFYV
APSQVAGEPGKLSCQLYQRSADIFLGVPFNIASYALLTHMVAQQCDLQVGDFIWTGGDCHIYSNHFEQVRTQLARQPYAY
PTLQIKRRPASIFDYAYEDFEVVGYEHHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-89 65