Gene Information

Name : thyA (Pnap_2772)
Accession : YP_982995.1
Strain : Polaromonas naphthalenivorans CJ2
Genome accession: NC_008781
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2915860 - 2916690 bp
Length : 831 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACCCGCCCAATCCGCCACCAGTACGAAGATCTCATGCGCCTTGTGGCCACGCAAGGTGCGTTCAAGGCCGACCGCAC
CGGCACCGGAACAAAAAGCGTGTTTGGCCACCAGATGCGCTTTGACCTGAACGAAGGCTTTCCGCTGGTCACGACCAAGA
AGGTCCACCTCAAGTCCATCATCCAGGAGCTGCTGTGGTTCCTGACCGGCTCCAGCAGCAACCACTGGCTGACCGAGCGC
GGCGTGACGATCTGGAACGAATGGGCGCGCGCGGACGGCGACCTTGGGCCGGTCTATGGCGTGCAGTGGCGCAGCTGGCC
GACGCCGGACGGCGGCCACATCGACCAGATCGCCGAGGTCATCAAGACCCTCAAGACCAACCCCGACTCGCGCCGCATCA
TCGTCAGCGCCTGGAACGTCGCCGACCTCGACAAGATGGCGCTGATGCCCTGCCACGCGCTGTTCCAGTTCTACGTCGCC
CCGGCCACCGAGGCCGGCGGCAAGGGCAAGCTGAGCTGCCAGTTGTACCAGCGCAGCGCCGACATCTTCCTGGGCGTGCC
GTTCAACATTGCCAGCTATGCCCTGCTGACGCACATGGTGGCGCAGCAGTGCGACCTGGACGTCGGCGACTTCATCTGGA
CCGGCGGCGACTGCCATATCTACAGCAACCACCAGGAACAGGTAGCCCTGCAACTGGGCCGCGCGCCTTTCGCCTATCCG
CTGCTCCACATCAGGCGCAAGCCCGATTCGATCTTCGACTACCAGTTCGAGGACTTCGAGTTCCTCGACTACCAGCACCA
TCCGGCCATCAAGGCGCCGGTGGCCGTTTAA

Protein sequence :
MTRPIRHQYEDLMRLVATQGAFKADRTGTGTKSVFGHQMRFDLNEGFPLVTTKKVHLKSIIQELLWFLTGSSSNHWLTER
GVTIWNEWARADGDLGPVYGVQWRSWPTPDGGHIDQIAEVIKTLKTNPDSRRIIVSAWNVADLDKMALMPCHALFQFYVA
PATEAGGKGKLSCQLYQRSADIFLGVPFNIASYALLTHMVAQQCDLDVGDFIWTGGDCHIYSNHQEQVALQLGRAPFAYP
LLHIRRKPDSIFDYQFEDFEFLDYQHHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 8e-89 65