Gene Information

Name : guaA (Pnap_2000)
Accession : YP_982230.1
Strain : Polaromonas naphthalenivorans CJ2
Genome accession: NC_008781
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2124230 - 2125852 bp
Length : 1623 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAGCACCAAAAAATCCTCATTCTCGATTTCGGCTCCCAGGTCACCCAGCTGATTGCCCGGCGGGTGCGCGAAGCCCA
TGTTTTCTGCGAAGTCCATCCTTGCGATGTGAGCGACGACTGGATTCGCGACTACGCCAAGGATGGCAACCTCAAGGGCA
TCATCCTGTCCGGCAGCCACGCCAGCATCTATGAAGAAACGACAGACAAGGCACCGCAAGTGGTGTTTGAACTGGGTATT
CCGGTGCTGGGCATCTGCTACGGCATGCAGGCCATGGCGCACCAGCTGGGTGGCAAGGTTGAGAGCGGCCACAAGCGCGA
ATTCGGCCATGCCGATGTGCGTGCCCGTGGCCACACGGCACTGCTCAAGGACATTGCCGACTTCACCACGCCCGAAGGGC
AGGGCATGCTCACGGTCTGGATGAGCCATGGTGACAAGGTCACGGAAATGCCGCCGGGCTTCAAGATCATGGCCTCTACC
TCCAGCTGCCCGATTGCCGGCATCGCTGACGAAGAGCGACGCTTCTACGGCGTGCAGTTCCACCCTGAAGTCACGCATAC
CAGGCAGGGGGCGGCAATCCTCAATCGCTTTGTGCTGGGCATCTGCGGCACCCGGCCCGATTGGGTCATGGGCGACTACA
TCAGCGAAGCAGTCGAGAAGATTCGCCAGCAAGTCGGCGATGAAGAAGTCATCCTGGGGTTGTCGGGCGGCGTCGATTCA
TCGGTGGCTGCGGCGCTGATTCACCGCGCCATCGGCGACCAGCTGACCTGCGTGTTTGTCGATCATGGTCTGCTGCGCCT
GAACGAGGGCGACATGGTGATGGAGATGTTTGTCGGCAAGCTGCACGCCAAGGTGATTCGCGTCGATGCCGCCGAGCAGT
TCCTGGGCCACCTCGCCGGCGTGAGCGACCCGGAGGCCAAGCGCAAGATCATCGGCCGCGAGTTCGTCGAAGTGTTCAAG
GCCGAGGCCGCGCGGCTCAAGGCCGGGCTGGATGGCGCCTACAAGGGCGCGAAATGGCTGGCCCAGGGAACGATTTACCC
AGACGTGATCGAGTCGGGCGGTGCCAAGAGCAAGAAAGCTGTTTCCATCAAGAGCCATCACAATGTCGGCGGCCTGCCTG
AGCAACTGGGCCTGAAGCTGCTCGAACCCCTGCGCGAACTGTTCAAGGACGAAGTGCGCGAACTGGGCGTGGCGCTGGGC
TTGCCGCACGACATGGTCTATCGCCATCCCTTCCCTGGGCCGGGCCTGGGCGTGCGGATTCTGGGTGAAGTCAAGAAAGA
CTATGCCGACCTGCTGCGCCGGGCCGACGCGATCTTCATCGAAGAACTGCGCAACTTCAAGGATGCCGAAACCGGCAAAA
CCTGGTACGACCTGACCAGCCAGGCGTTCACGGTGTTTCTGCCGGTGAAAAGCGTCGGCGTGATGGGCGATGGCCGCACC
TATGAATACGTGGTGGCCTTGCGCGCGGTGCAAACCAGCGACTTCATGACCGCCGACTGGGCCGAACTGCCTTATGCGCT
GCTTAAAAAAGTGTCGGGCCGAATCATCAATGAAGTGCGCGGCATCAACCGCGTGACCTACGATGTCAGCAGCAAGCCGC
CAGCGACGATTGAGTGGGAGTAG

Protein sequence :
MQHQKILILDFGSQVTQLIARRVREAHVFCEVHPCDVSDDWIRDYAKDGNLKGIILSGSHASIYEETTDKAPQVVFELGI
PVLGICYGMQAMAHQLGGKVESGHKREFGHADVRARGHTALLKDIADFTTPEGQGMLTVWMSHGDKVTEMPPGFKIMAST
SSCPIAGIADEERRFYGVQFHPEVTHTRQGAAILNRFVLGICGTRPDWVMGDYISEAVEKIRQQVGDEEVILGLSGGVDS
SVAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMEMFVGKLHAKVIRVDAAEQFLGHLAGVSDPEAKRKIIGREFVEVFK
AEAARLKAGLDGAYKGAKWLAQGTIYPDVIESGGAKSKKAVSIKSHHNVGGLPEQLGLKLLEPLRELFKDEVRELGVALG
LPHDMVYRHPFPGPGLGVRILGEVKKDYADLLRRADAIFIEELRNFKDAETGKTWYDLTSQAFTVFLPVKSVGVMGDGRT
YEYVVALRAVQTSDFMTADWAELPYALLKKVSGRIINEVRGINRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-117 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-117 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-118 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-105 48