Gene Information

Name : BCG_0498 (BCG_0498)
Accession : YP_976596.1
Strain : Mycobacterium bovis BCG Pasteur 1173P2
Genome accession: NC_008769
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 580490 - 582013 bp
Length : 1524 bp
Strand : +
Note : -

DNA sequence :
ATGACTGTCTTTTCCCGTCCCGGTTCCGCCGGGGCGCTGATGTCCTATGAATCCCGGTACCAAAACTTCATCGGGGGCCA
GTGGGTCGCGCCGGTCCATGGGCGCTACTTCGAGAACCCGACGCCGGTGACCGGCCAGCCGTTCTGCGAGGTGCCGCGCT
CCGACGCGGCCGACATCGACAAGGCGCTCGACGCCGCGCACGCGGCGGCGCCGGGGTGGGGCAAGACCGCACCGGCCGAA
CGGGCGGCGATCCTCAACATGATTGCCGACCGCATCGACAAGAACGCCGCCGCGCTGGCGGTGGCCGAGGTCTGGGACAA
CGGGAAACCGGTCCGGGAAGCGCTGGCCGCCGATATCCCGTTGGCGGTCGATCACTTCCGGTACTTCGCCGCGGCGATTC
GCGCCCAGGAGGGCGCGCTGAGCCAGATCGACGAGGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTGGGC
CAGATCATTCCGTGGAACTTCCCCATCCTGATGGCGGCCTGGAAGCTGGCGCCGGCGTTGGCGGCCGGCAACACGGCGGT
GCTCAAACCCGCCGAGCAGACACCCGCTTCGGTGCTCTACCTGATGTCGCTGATCGGTGATCTGTTGCCGCCCGGGGTGG
TCAACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGTTGGCCTCCAGCGACCGCATCGCCAAGGTCGCGTTCACC
GGGGAAACCACCACGGGGCGGCTGATCATGCAATACGCCTCGCACAACCTGATCCCGGTCACCCTGGAACTCGGCGGCAA
GAGCCCCAACATCTTCTTCGCCGACGTGCTGGCCGCCCACGACGACTTCTGCGACAAGGCGCTGGAAGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCAGTCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG
CTGGCGGCGATCCGGACCAAGGCGGTCCGGCAGGGCGACCCGCTGGACACCGAAACCATGCTGGGTTCCCAGGCCTCCAA
CGACCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGCAAGAGGGTGCGGTGATTATCGCCGGAGGCGAGCGCG
CCGAACTAGGCGGCGACCTGTCCGGCGGTTATTACATGCAGCCGACGATCTTCACCGGCACCAACAACATGCGGATTTTC
AAGGAGGAGATCTTCGGGCCGGTGGTCGCGGTGACGTCGTTCACCGATTACGACGACGCGATCGGCATCGCCAACGACAC
CCTCTACGGCTTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACACTGCCTATCGGGCCGGGCGGGACATCCAGGCCGGCC
GGGTGTGGGTCAACTGCTACCACCTCTACCCCGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAG
GGCCACCAGATGATGCTGCAGCACTACCAGCACACCAAGAACCTGCTGGTGTCCTACTCGGATAAGGCGCTGGGGTTCTT
CTGA

Protein sequence :
MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAE
RAAILNMIADRIDKNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAAAIRAQEGALSQIDEDTVAYHFHEPLGVVG
QIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE
LAAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIF
KEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGRE
GHQMMLQHYQHTKNLLVSYSDKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-128 60
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 59
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-134 59
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCG_0498 YP_976596.1 aldehyde dehydrogenase VFG0082 Protein 2e-128 60