Gene Information

Name : guaB1 (BCG_1879c)
Accession : YP_977969.1
Strain : Mycobacterium bovis BCG Pasteur 1173P2
Genome accession: NC_008769
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.205
Position : 2093225 - 2094664 bp
Length : 1440 bp
Strand : -
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
GTGATGAGATTTCTAGACGGGCACCCACCCGGGTACGACCTGACATACAACGACGTGTTCATCGTTCCGAACCGATCCGA
GGTCGCGTCGCGCTTCGACGTCGATTTGTCCACCGCCGACGGCTCGGGCACCACCATTCCGGTAGTGGTCGCCAATATGA
CCGCGGTAGCCGGGCGGCGGATGGCCGAGACGGTCGCCCGCCGCGGTGGCATCGTAATCCTGCCGCAGGATCTGCCGATC
CCGGCGGTAAAGCAGACGGTGGCGTTCGTCAAAAGCCGGGACCTGGTGCTCGACACCCCAGTGACGCTGGCACCCGACGA
TTCGGTGTCCGACGCCATGGCGCTCATCCACAAGCGCGCACATGGCGTCGCGGTGGTCATCCTCGAGGGTCGCCCGATCG
GATTGGTGCGCGAATCGTCCTGCCTGGGCGTGGATCGCTTCACCCGGGTGCGCGATATCGCCGTGACGGACTATGTGACC
GCTCCAGCGGGAACCGAGCCACGCAAGATCTTCGACCTGCTGGAGCACGCCCCGGTCGACGTTGCGGTGCTGACCGACGC
CGACGGCACGTTGGCGGGAGTGCTAAGCCGCACCGGGGCTATCCGCGCCGGTATCTACACCCCGGCCACCGATAGCGCGG
GCCGGCTGCGGATCGGCGCGGCCGTCGGCATCAACGGCGACGTGGGCGCTAAGGCCCGAGCGCTCGCCGAAGCCGGCGTC
GACGTGCTGGTCATCGACACCGCACACGGACACCAGGTCAAGACCTTGGACGCGATCAAGGCGGTCTCGGCACTGGACTT
GGGTTTGCCGCTGGCGGCGGGAAACGTGGTGTCGGCGGAGGGCACCCGGGATCTGCTGAAAGCCGGGGCGAACGTCGTCA
AGGTCGGTGTCGGCCCCGGCGCCATGTGCACCACCCGAATGATGACCGGTGTCGGCCGCCCGCAGTTCTCCGCTGTGCTC
GAATGCGCTTCTGCGGCAAGGCAGCTCGGTGGTCATATCTGGGCCGACGGTGGGATCCGGCATCCACGCGACGTGGCTCT
GGCGCTGGCCGCCGGCGCCTCGAACGTGATGATCGGATCGTGGTTCGCCGGCACCTACGAATCCCCCGGAGACCTGATGC
GTGACCGCGACGATCAGCCGTACAAGGAGAGCTACGGCATGGCATCCAAGCGGGCGGTGGTGGCCCGGACCGGCGCGGAC
AACCCGTTCGACCGAGCTCGTAAGGCGTTGTTCGAGGAAGGCATCTCGACGTCGCGGATGGGCCTTGACCCCGACCGCGG
AGGTGTGGAGGACCTAATTGACCACATCACTTCTGGCGTGCGCAGCACCTGCACCTATGTGGGTGCCTCGAACCTGGCGG
AGCTGCATGAGCGGGCCGTGGTGGGCGTGCAGTCGGGAGCGGGCTTTGCCGAGGGCCATCCGCTGCCCGCCGGCTGGTGA

Protein sequence :
MMRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPI
PAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVT
APAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGV
DVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVL
ECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGAD
NPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 4e-132 58
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 4e-132 58
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 3e-132 58
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-132 58