Gene Information

Name : tkt (BCG_1510c)
Accession : YP_977602.1
Strain : Mycobacterium bovis BCG Pasteur 1173P2
Genome accession: NC_008769
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1652909 - 1655011 bp
Length : 2103 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACCACACTCGAAGAGATCTCCGCGCTTACCCGACCGCGCCATCCCGACGACTGGACCGAGATCGATTCGGCTGCCGT
CGACACCATCCGGGTATTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTGGCTC
CGTTGGCCTACACGCTGTTTCAGCGGACAATGCGTCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTT
TTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATTGA
GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCC
CGCTGGGGCAGGGACTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAGCGCGGCCTGTTCGACCCGGACGCC
GAACCGGGCGCCAGCCCCTTCGACCACTACATCTATGTCATCGCCTCCGACGGTGACATCGAAGAAGGGGTGACCTCGGA
GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACG
ACACCAACATCGCGCTGTGTGAGGACACCGCGGCCCGCTACCGCGCGTACGGCTGGCACGTGCAAGAGGTTGAGGGCGGT
GAGAACGTCGTCGGCATCGAGGAGGCCATCGCCAATGCGCAGGCGGTCACCGACCGGCCCTCGTTCATCGCGCTGCGCAC
CGTCATCGGCTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGACGACGAGGTGGCCG
CAGTCAAGAAGATCGTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTG
GTGGCCCGCGGCAAACAGGCCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCGCGGCGTGAACCCGAGCGCAAGGC
GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCCCACTGGGAACCGGGGTCCAAGG
CGCTGGCCACCCGTGCGGCCTCGGGTGCGGTGCTGTCCGCGCTCGGGCCGAAACTGCCCGAGTTGTGGGGCGGTTCGGCC
GACCTGGCGGGCAGCAACAACACAACGATAAAGGGCGCCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAGTACAC
CGCGCACTGGTATGGTCGCACCTTGCACTTCGGTGTTCGCGAGCACGCGATGGGTGCCATCCTGTCCGGCATCGTGCTGC
ACGGACCCACCCGGGCTTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCGGCGGTGCGGCTGGCGGCGTTG
ATGGACATCGACACCATCTACGTCTGGACGCACGACTCGATCGGCCTCGGCGAAGACGGGCCCACCCATCAACCGATCGA
GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACAGCCTACGCCTGGC
GCACGATCCTGGCCCGCCGCAACGGCAGCGGGCCGGTCGGGTTGATCCTGACCCGCCAGGGTGTGCCGGTGCTGGACGGC
ACCGACGCCGAGGGGGTTGCCCGCGGCGGTTACGTGCTGAGTGACGCCGGTGGTCTGCAACCGGGCGAGGAACCCGACGT
CATTCTCATCGCCACCGGCTCGGAGGTGCAGCTGGCGGTCGCGGCGCAGACGTTGCTGGCGGACAACGACATCCTCGCTC
GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG
TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCAGCTGGTTGGCGACACGGGCGAGATCGTCTCGAT
CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCG
CCGAACGAGCGCTGGATAACTGA

Protein sequence :
MTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV
LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
EPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGG
ENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGL
VARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSA
DLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAAL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDG
TDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV
SARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-113 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-112 42