Gene Information

Name : purA (NMC0765)
Accession : YP_974851.1
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 782060 - 783364 bp
Length : 1305 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGGCTATGGCTAAAAATGTTGTAGTAATCGGCGCACAGTGGGGCGACGAGGGTAAAGGTAAAATCGTTGACTGGCTGGC
GGAAGAAGCCGGCGGCGTGGTGCGCTTCCAAGGCGGCCACAATGCGGGTCATACTTTGGTCGTCGGCGGCAAAAAAACCA
TTTTGCGCCTGATTCCGAGCGGCATCCTGCATGAAAGTCTGGACTGCTTCATCGGTTCGGGCGTTGTCGTCTCCCCCGAA
GCCCTGTTGGGCGAAATCGACGAGTTAAACGCTGCAGGCGTGAAAAACGTCGAAGGCCGTCTGAAAATCGCGCCGACCTG
CCCGCTGATCCTGCCTTACCACATCGCGCTCGACCAAGCCCGCGAAGCATCGCGCGGCAAAGGCAAAATCGGCACGACCG
GCCGCGGCATCGGCCCTGCCTACGAAGACAAAGTGGCACGCCGCGCCATTCGCGCCGCCGATTTGCTGCATCCTGAAAAA
CTGCGTGAAAAACTGGATGCCATCCTTGCCTATTACAATGTCCAACTGCAACATCTGCACAATGCCGAGCCGGTTAAAGC
GGAAGACGTGATGGCGGTTATCGAAAAAGTCGCGCTGCGCATTGCGCCGATGATTACCGACGTGTCCCGCGTGTTGAACG
AGAAAAACAAAAACGGCGAAAAACTGCTGTTTGAAGGCGCGCAAGGTGCGTTGTTGGACATCGACTACGGCACTTATCCC
TTCGTTACCTCGTCCAACTGTCTGGCGGGAGCCGCTTCCGCAGGCGCGGGCGTAGGCCCTCAAATGCTGGATTATGTTTT
GGGCATCGTCAAAGCCTATACCACGCGCGTCGGTTCAGGCCCGTTCCCGACCGAATTGTTCGACGAAGTAGGCGCAGGTT
TGGCGGAACGCGGACACGAATTCGGCTCGGTAACCGGCCGCGCACGCCGCTGCGGCTGGTTTGATGCCGCCGCCCTGAAA
CGCTCCATCCAAATCAACGGCATTTCCGGTATGTGCATTACCAAACTCGATGTAATGGACGGCGTTGAAACCATCAATAT
CTGCGTCGGCTACGAATTGCCCGACGGCGGCAAAACCGATATCCTGCCTTGCGGTTCCGATGCGGTGGAAACCTGCAAGC
CGATTTACGAAACCATGCCCGGCTGGCGTGAATCCACTTTCGGCGTGAAAAGCTACGACGCATTACCTGCCAATGCCAAA
GCATATTTGAAACGGATTGAAGAAGTCTGCGGTGCGCCGGTCGCCATCGTCTCCACCGGCCCCGACCGAGAAGAAACGAT
TGTGCTGCATCATCCGTTCGCATAA

Protein sequence :
MAMAKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTLVVGGKKTILRLIPSGILHESLDCFIGSGVVVSPE
ALLGEIDELNAAGVKNVEGRLKIAPTCPLILPYHIALDQAREASRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEK
LREKLDAILAYYNVQLQHLHNAEPVKAEDVMAVIEKVALRIAPMITDVSRVLNEKNKNGEKLLFEGAQGALLDIDYGTYP
FVTSSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVGSGPFPTELFDEVGAGLAERGHEFGSVTGRARRCGWFDAAALK
RSIQINGISGMCITKLDVMDGVETINICVGYELPDGGKTDILPCGSDAVETCKPIYETMPGWRESTFGVKSYDALPANAK
AYLKRIEEVCGAPVAIVSTGPDREETIVLHHPFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 7e-88 48