Gene Information

Name : lipA (NMC0066)
Accession : YP_974205.1
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 78134 - 80248 bp
Length : 2115 bp
Strand : +
Note : -

DNA sequence : 
ATGTTCCTCTTTTCAGACGGCCTACAATCCATTAATAACAATAATCGACGAAAACGCATTGTGAAAAACGCCTACATCCC
CTCTCGTGGCATCCGCAAAATCCCCCATCTCTTCACCCTATTGCCTGAGTTTCATATCTGCAAGGATGGGAAAGGAGCAG
AGGCTGTTATCGGCTGGGGTTTGCGCCCGACGACACACAAAGCGCGTGCTTTTGCCGCTGAACACCAGCTTCCCTTTATT
GCTTTGGAAGACGGCTTTTTACGCTCGCTTGGCCTGGGCGTTGCCGGCTATCCTCCCTATTCCATCGTCTATGACGACAT
CGGCATCTACTACGACACTACCCGCCCTTCTCGTTTGGAACAACTGATTCTTGCCGCCGATACCATGCCGTCTGAAACCT
TGGCTCAGGCGCAACAGACGATGGATTTCATCCTGCAACACCACCTGTCCAAATACAACCACGCGCCCGAACTTTCAGAC
GATCATCCTTTACGCTCCCCATCCAAGCCTGAAACTGTCCTCATTATCGACCAAACCTTCGGCGATATGGCCATCCAATA
TGGCGGCGCAGATGCCTCTACGTTTGAACTGATGTTTCAGACGGCCTTGAATGAAAACCCGCAAGCCGATATCTGGGTAA
AAACCCATCCCGATGTTTTGTGCGGCAAAAAACAAGGCTATCTGACCCAACTGGCGCAGCAACACCGCGTCCATCTTCTG
GCAGAAGACATCAACCCGATTTCTTTGTTGCAAAACGTCGATAAAGTTTATTGCGTTACCTCGCAAATGGGTTTTGAGGC
GCTTTTGTGCGGCAAGCCGCTGACCACCTTCGGCCTGCCGTGGTATGCCGGATGGGGTGTAAGCGACGACCGCCATCCTG
AAATCAACCGCCTTGTTCAAACCCAACGCCGCGCCACCCGCAACTTGCTGCAGCTCTTCGCCGCAGCCTATCTGCAATAC
AGCCGCTACCTCAACCCCAATACCGGCGAAGCAGGCAGCCTCTTTGATGTCATCGACTATTTGGCGACGGTCAAACGTAA
AAACGACAAATTGCGTGGCGAGTTATATTGCGTCGGTATGTCTTTGTGGAAACGCGCGGTTGCCAAACCGTTCTTTAACG
TACCCTCTTGCCGTCTGAAATTTATCTCTTCCACCCAAAAACTGGCAAGGGTCAAACTGTCCGACGATGCACGCATCCTG
GCTTGGGGCAACGGCAAAGAGGCCATCGTCCGCTTTGCCGAACAACACCACATCCCCCTGCTGCGCATGGAAGACGGCTT
TATCCGCTCGGTCGGACTCGGCTCCAACTTAGTGCCGCCGCTGTCGCTCGTTACCGACGATATGAGCATTTATTTCAATG
CCGAAACCCCGTCCCGTCTTGAATACATCCTACAAAACCAAAACTTCGACGATCAAGACTTTCAGACGGCCTTGAAGCTG
CAAAAAATGCTGACTGAAAACCACATCAGCAAATACAACGTCGGCAACTCAGACTTCAGCGCCCCATCAACCGACAAAAC
CGTGATCCTCGTTCCCGGCCAGGTTGAAGATGATGCGTCTATCCGCTACGGTTCGCCCCAAATCTACCGCAATCTGGATT
TGCTCCGTACCGTACGCGAACGCCATCCCGATGCCTATATCATCTACAAACCGCATCCCGATGTAGTCAGCGGTAACCGC
ATCGGCCATATTTCCCCTGAAGATGCTGCACGATATGCCGACCAAACCGCCGAACAAGCCGACATCCTGACCTGTCTCCA
ATACGCAGACGAAATACATACCATGACTTCGCTGACCGGTTTTGAAGCCTTGTTGCGCGGCAAAAAAGTCAGCTGCTACG
GCCTGCCTTTTTACGCAGGCTGGGGGCTTACCCAAGATCTGCTCCCCATCCCGCGCCGTAGCCGCAGACTTGAGCTTTGG
CAGCTGATTGCCGGCACGCTCATCCACTATCCCGACTACATCCACCCCGAAACCCATCAGGCCATAAATGCAGAAACCGC
AGCCCAAATCCTGATACGACAAAAAAATATGCAAAAAAACAACAACGGATTACATCGCGGGTACTTTGCCAAAAAATTAG
GTAAAATCAAACAACTATATCGATCTTTCAAATAA

Protein sequence : 
MFLFSDGLQSINNNNRRKRIVKNAYIPSRGIRKIPHLFTLLPEFHICKDGKGAEAVIGWGLRPTTHKARAFAAEHQLPFI
ALEDGFLRSLGLGVAGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTMPSETLAQAQQTMDFILQHHLSKYNHAPELSD
DHPLRSPSKPETVLIIDQTFGDMAIQYGGADASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLAQQHRVHLL
AEDINPISLLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPEINRLVQTQRRATRNLLQLFAAAYLQY
SRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARIL
AWGNGKEAIVRFAEQHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
QKMLTENHISKYNVGNSDFSAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTVRERHPDAYIIYKPHPDVVSGNR
IGHISPEDAARYADQTAEQADILTCLQYADEIHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELW
QLIAGTLIHYPDYIHPETHQAINAETAAQILIRQKNMQKNNNGLHRGYFAKKLGKIKQLYRSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 99
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 1e-132 49
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 8e-133 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lipA YP_974205.1 capsule polysaccharide modification protein VFG0259 Protein 0.0 99
lipA YP_974205.1 capsule polysaccharide modification protein VFG0704 Protein 6e-158 58
lipA YP_974205.1 capsule polysaccharide modification protein VFG0692 Protein 5e-180 57