Gene Information

Name : kdsB (NMC0624)
Accession : YP_974716.1
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 647972 - 648733 bp
Length : 762 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACCGAATTCGTCGTATTGATTCCGGCGCGGCTGGATTCGTCGCGCCTGCCCGGAAAAGCCTTGGCGGACATCCACGG
CAAACCGATGGTCGTGCGCGTTGCCGAACAGGCGGCAAAAAGTAAAGCCGCGCGCGTCGTCGTCGCCACCGACCATCCCG
ACATTCAGACAGCCTGTCAGGCGCACGGTATCGAAGTCGTCATGACTTCAAACCGGCACGAAAGCGGCACGACGCGCCTT
GCCGAAGCCTCTGCCGCGCTGAAGCTGCCGCCGCATCTGGTGGTTGTCAACGTACAGGGCGACGAGCCGCTGATTGCCCC
CGAACTCATCGACCGCACTGCCGAAGTCTTGGTGGAAAACAACGTACAGATGGCAACTGCGGCACACGAATTGCACGATT
TCGACGAATTGATGAATCCCAATGCCGTCAAAGTCGTCCTCGACAAAAACCGCAACGCCATCTACTTCAGCCGCGCCCCG
ATTCCCTATCCGCGCGATGCGATGCGTGCAGGAAAACGCGAAATGCCGTCTGAAACCGCCGTCCTGCGCCATATCGGCAT
CTACGCTTACCGCGCCGGCTTCCTGCAACGCTATGCCGAAATGAGCGTTTCGCCGCTGGAAACCATCGAATCGCTGGAAC
AGCTGCGCGTCCTGTGGCACGGCTACCCGATTGCCGTCGAAACCGCCAAAGAAGCCCCCGCCGCCGGTGTGGATACGCAG
GAAGATTTGGATAGGGTTCGCGCTGTATTTCAGACCGTATAA

Protein sequence : 
MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTACQAHGIEVVMTSNRHESGTTRL
AEASAALKLPPHLVVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
IPYPRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQ
EDLDRVRAVFQTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-31 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-31 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-31 43