Gene Information

Name : mutS (NMC2138)
Accession : YP_976048.1
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 2178761 - 2181355 bp
Length : 2595 bp
Strand : +
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGTCCAAATCCGCCGTTTCCCCAATGATGCAGCAATACCTCGGCATCAAAGCGCAACATACCGACAAACTGGTGTTTTA
CCGTATGGGCGATTTTTACGAGATGTTTTTCGACGATGCGGTAGAAGCGGCAAAACTTTTGGATATTACCCTGACCACGC
GCGGACAGGTGGATGGCGAGCCGGTCAAAATGGCAGGCGTGCCGTTTCACGCCGCCGAACAATATCTGGCGCGCCTGGTC
AAGTTGGGCAAAAGCGTGGCGATTTGCGAACAGGTCGGCGAAGTCGGCGCAGGCAAAGGACCGGTGGAGCGCAAAGTCGT
GCGCATCGTAACGCCCGGCACGCTGACCGATTCCGCATTGCTGGAAGACAAGGAAACCAACCGCATCGTTGCCGTGTCCC
CCGACAAAAAATACATCGGTTTGGCGTGGGCATCGCTGCAAAGCGGCGAATTCAAAACCAAGCTGACAACTGTGGATAAA
TTGGACGACGAACTGGCGCGCCTGCAGGCGGCGGAAATTCTGTTGCCTGACAGTAAAAACGCACCGCAACTTCAGACGGC
ATCGGGTGTTACGCGCCTGAACGCGTGGCAGTTTGCCGCCGACGCGGGGGAAAAACTGCTGACGGAATATTTCGGCTGCC
AGGATTTGCGCGGCTTCGGTTTGGACGGCAAAGAACACGCCGTTGCGATTGGCGCGGCAGGTGCACTGTTGAACTATATC
CGTCTGACGCAAAACCTGATGCCGCAACATTTGGACGGCCTGTCGCTCGAAACCGACAGCCAATATATCGGTATGGATGC
CGCCACGCGCCGCAATCTCGAAATCACGCAAACCCTCTCCGGCAAAAAATCGCCGACCCTGATGTCCACGCTCGACCTTT
GCGCTACCCATATGGGCAGCCGCCTCTTGGCTCTCTGGCTGCACCACCCTTTACGCAACCGCGCCCACATCCGAGCGCGC
CAAGAAGCCGTTGCCGCGCTGGAAAGCCAATACAAACCCCTCCAATGCCGTCTGAAAAACATTGCGGACATTGAACGCAT
TGCTGCCCGCATCGCCGTCGGCAACGCCCGCCCGCGCGATTTGGCATCTTTACGCGACAGTCTGTTCGAGTTGGCACAAA
TCGACTTGTCCGCAAACGGCAGCAGCCTGTTGGAAACCCTCAAAGCCGTTTTCCCTGAAAACCTATCCACAGCCGAACAG
CTCCGCCAAGCCATTTTGCCCGAACCTTCCGTCTGGCTGAAAGACGGCAATGTCATCAACCACGGTTTTCATCCCGAACT
GGACGAATTGCGCCGCATTCAAAACCATGGCGACGAATTTTTGCTGGATTTGGAAGCCAAGGAACGCGAACGTACCGGTT
TGTCCACACTCAAAGTCGAGTTCAACCGCGTTCACGGCTTTTACATTGAATTGTCCAAAACCCAAGCCGAACAAGCACCT
GCCGACTACCAACGCCGGCAAACCCTCAAAAACGCCGAACGCTTCATCACGCCGGAGTTGAAAGCCTTTGAAGACAAAGT
GCTGACTGCTCAAGAGCAAGCCCTCGCCTTAGAAAAACAACTCTTTGACGGCGTATTGAAAAACCTTCAGACGGCATTGC
CGCAGCTTCAAAAAGCCGCCAAAGCCGCCGCCGCGCTGGACGTGTTGTCCACATTTTCAGCCTTGGCAAAAGAGCGGAAC
TTCGTCCGCCCCGAGTTTGCCGACTATCCGGTTATCCACATCGAAAACGGCCGCCATCCCGTTGTCGAACAGCAGGTACG
CCACTTCACCGCCAACCACACCGACCTTGACCACAAACACCGCCTCATGCTGCTCACCGGCCCCAATATGGGCGGCAAAT
CCACCTACATGCGCCAAGTCGCGCTGATTGTTTTATTGGCACACACCGGCTGTTTTGTGCCTGCCGATGCCGCCACAATC
GGGCCCATCGATCAAATCTTCACCCGCATCGGCGCATCGGACGACCTCGCCTCCAACCGCTCCACTTTCATGGTCGAAAT
GAGCGAAACCGCCTACATCCTGCATCACGCCACCGAACAAAGCCTTGTTTTAATGGACGAAGTCGGACGTGGTACTTCCA
CTTTCGACGGCCTCGCCCTCGCGCACGCCGTTGCCGAACACCTGCTGCAAAAAAACAAATCCTTCAGCCTGTTTGCTACC
CACTATTTCGAGCTGACCTACCTGCCCGAAGCCCACGCCGCCGCCGTCAATATGCACCTTTCCGCGCTCGAACAGGGACA
GGACATCGTTTTCCTGCACCAAATCCAACCGGGTCCCGCCGGCAAAAGCTACGGCATCGCCGTTGCCAAACTCGCCGGCC
TGCCTGTACGCGCATTGAAATCCGCCCAAAAGCATTTGAACGGACTGGAAAACCAAGCCGCCGCAAACCGTCCCCAACTG
GATATTTTCAGTACCATGCCGTCTGAAAAAGGAGATGAACCGAATGTGGGCAACTTTGTGGACAAAGCAGAGGAAAAACA
TTTTGAAGGTATATTGGCAGCAGCCTTGGAAAAACTCGATCCCGACAGCCTGACCCCGCGCGAAGCATTGTCAGAACTGT
ACCGTCTGAAAGATTTGTGCAAATCCGTATCTTAA

Protein sequence :
MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAAKLLDITLTTRGQVDGEPVKMAGVPFHAAEQYLARLV
KLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
LDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDGKEHAVAIGAAGALLNYI
RLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNRAHIRAR
QEAVAALESQYKPLQCRLKNIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSANGSSLLETLKAVFPENLSTAEQ
LRQAILPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAP
ADYQRRQTLKNAERFITPELKAFEDKVLTAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERN
FVRPEFADYPVIHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATI
GPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFAT
HYFELTYLPEAHAAAVNMHLSALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNGLENQAAANRPQL
DIFSTMPSEKGDEPNVGNFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRLKDLCKSVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 6e-168 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_976048.1 DNA mismatch repair protein MutS VFG0562 Protein 3e-178 50