Gene Information

Name : serS (NMC1602)
Accession : YP_975570.1
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1635786 - 1637081 bp
Length : 1296 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATCCAATTGCTCCGCAGCAACACCGCCGCCGTTGCCGAACGGCTTGCACGGCGCGGTTATGACTTTGATAC
CGCACGTTTTGACGCACTGGAAGAACGACGCAAGTCCGTTCAGGTGAAAACCGAAGAATTACAAGCCTCGCGTAACAGCA
TTTCCAAGCAAATCGGCGCACTGAAAGGTCAGGGCAAACACGAAGAGGCACAGGCGGCCATGGATCAAGTCGCCCAAATC
AAAACCGATTTGGAACAGGCAGCCGCCGATTTGGAAGCCGTGCAAAAGGAACTGGACGCATGGCTGTTGAGCATTCCGAA
CCTGCCGCATGAGGACGTGCCTTTCGGTAAGGATGAAACCGAAAACGTCGAAGTCCGCAAAGTCGGCACCCCGCGCGAAT
TTGACTTTGAAATCAAAGACCATGTCGATTTGGGCGAACCTTTGGGTTTGGATTTCGAAGGTGGCGCGAAACTTTCCGGC
GCACGATTTACCGTGATGCGCGGACAAATCGCCCGTCTGCACCGCGCCTTGGCACAGTTCATGCTGGATACGCACACGCT
GCAACACGGCTACACCGAGCATTACACGCCTTATATCGTTGACGATACGACGCTGCAAGGTACGGGCCAACTACCAAAAT
TTGCGGAAGATCTGTTCCACGTTACCCGTGGCGGCGACGAAACCAAAACCACCCAATACCTGATTCCGACAGCCGAAGTT
ACCCTGACCAATACCGTTGCCGACAGCATTATCCCGTCCGAACAACTGCCGCTGAAGCTGACCGCGCATTCGCCCTGTTT
CCGCAGCGAGGCGGGTTCGTACGGCAAAGACACGCGCGGTCTGATTCGCCAGCACCAGTTCGACAAAGTAGAAATGGTAC
AAATCGTTCATCCCGAAAAATCATACGAAGCACTGGAAGAAATGGTCGGCCATGCCGAAAACATCCTGAAGGCTTTGGAA
CTGCCCTACCGCGTGATTACCCTGTGTACCGGCGACATGGGCTTCGGCGCAACCAAAACGTATGACTTGGAAGTTTGGGT
TCCCGCGCAAAATACCTACCGCGAAATCTCAAGCTGCTCCAACTGCGAAGATTTCCAAGCCCGCCGCATGAAGGCGCGTT
TCAAAGACGAAAACGGCAAAAACCGCTTGGTACATACTTTGAACGGCTCCGGCTTGGCTGTCGGCAGAACGCTGGTCGCC
GTATTGGAAAACCATCAAAACGCCGACGGCAGCATCAACATCCCTGCCGCACTGCAACCGTATATGGGCGGCGTTGCCAA
GTTGGAAGTGAAATAA

Protein sequence :
MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGALKGQGKHEEAQAAMDQVAQI
KTDLEQAAADLEAVQKELDAWLLSIPNLPHEDVPFGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSG
ARFTVMRGQIARLHRALAQFMLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQYLIPTAEV
TLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYEALEEMVGHAENILKALE
LPYRVITLCTGDMGFGATKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVA
VLENHQNADGSINIPAALQPYMGGVAKLEVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-101 55