Gene Information

Name : tkt (NMC1395)
Accession : YP_975388.1
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1392793 - 1394772 bp
Length : 1980 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCTCAACTGGCAAACGCAATCCGCTTCCTCTCGGCCGATGCCGTTCAAAAAGCCAATTCCGGCCACCCCGGCGCACC
TATGGGTATGGCGGAAATGGCGGAAACATTGTGGACGAAATTCCTCAATCACAACCCCGCCAACCCCAAATTCTACAACC
GCGACCGCTTCGTCCTCTCCAACGGCCACGCGTCTATGCTGTTGTACAGCCTGCTGCACCTGACCGGCTACAACCTAAGC
ATTGAAGACTTGAAAAACTTCCGCCAACTGCACAGCAAAACCCCCGGCCATCCCGAATACGGCTACACCGACGGCGTGGA
AACCACGACCGGCCCGTTGGGGCAAGGGATTGCCAACGCGGTGGGTATGGCATTGGCAGAAAAAATCCTTGCCGCCGAAT
TTAATAAAGACGGTTTGAACATCGTCGATCATTACACCTACGTCTTTATGGGCGACGGCTGTCTGATGGAAGGCGTATCG
CACGAAGCCTGTTCGCTCGCCGGCACCTTGGGCTTGGGCAAACTGATTGTTTTATATGATGACAACAATATTTCCATTGA
TGGTAAAGTGGACGGCTGGTTTACCGAAAACATCCCGCAACGCTTTGAAAGCTACGGCTGGCACGTCGTTCCTAACGTAA
ATGGTCATGACACCGCCGCCATTCAAGCCGCCATCGAAGCCGCACGTGCCGAAACCGGCAAACCGTCCATCATCTGCTGT
AAAACCTTAATCGGCAAAGGCAGTGCCAATAAAGAAGGCAGCCACAAAACCCACGGCGCACCTTTGGGTGCGGACGAAAT
CGAAGCCACGCGCAAACATTTGGGCTGGACTTACCCTGCCTTTGAAATCCCGCAAGAAATTTACGATGCGTGGAATGCCA
AAGAAAAAGGCGCGAAACTGGAAGCCGAATGGGACAAACTGTTCGCGCAATACCAAGCCAAATATCCTGCCGAAGCCGCA
GAATTTGTGCGCCGTATGGATAAAAAACTGCCGGAAAACTTTGACGGGTACGTTCAGACGGCATTGAAAGAAGTGTGCGC
CAAAGCCGAAACCGTCGCCACCCGCAAAGCCAGCCAAAACAGCATCGAAATCTTGGCAAAAGAGCTGCCCGAACTGGTGG
GCGGCTCTGCCGACCTGACCCCGTCCAATCTGACCGACTGGTCAAACAGCGTCTCCGTTACCCGCGACAAAGGCGGCAAC
TACATCCACTACGGCGTGCGCGAGTTCGGCATGGGTGCGATTATAAACGGCTTGGTATTGCACGGCGGCGTGAAACCCTT
TGGCGCGACCTTCCTGATGTTCAGCGAATACGAGCGCAACGCCCTGCGTATGGCGGCACTGATGAAAATCAACCCCGTGT
TCGTGTTCACCCACGATTCCATCGGTTTGGGCGAAGACGGCCCAACCCACCAGCCGATTGAGCAAACCGCCACCCTGCGC
CTGATTCCGAATATGGACGTATGGCGGCCGTGCGACACCGCCGAATCCTTGGTCGCTTGGGCAGAAGCCGTCAAAGCCGC
CGATCACCCGTCCTGCCTGATTTTCAGCCGTCAAAACCTGAAATTCCAAGCGCGCAGCGAACAACAACTGAACGACATCA
AACGCGGCGGCTACGTCATCAGCGAAGCCCAAGGCAACGCCCAAGCCGTCATCATTGCCACCGGTTCCGAAGTCGAGCTG
GCTTTGGAAGCGCAAAAAGCACTCGCCGCGCAAAACATCGCCGTGCGCGTCGTTTCCATGCCGTCCACCAACGTATTCGA
CCGCCAAGACACCGCCTATCAAGCCGCCGTCCTGCCCGAAGGCCTGCCGCGCATTGCCGTAGAAGCCGGACACGCCGACG
GCTGGTACAAATACGTCGGCCTGAACGGCGCAGTCGTCGGCATCAACCGCTTCGGCGAATCCGCCCCTGCCGATCTGCTG
TTCAAAGAATTCGGCTTTACCGTGGACAATGTGGTCGATACAGTGAAATCAGTGCTGTAA

Protein sequence :
MSQLANAIRFLSADAVQKANSGHPGAPMGMAEMAETLWTKFLNHNPANPKFYNRDRFVLSNGHASMLLYSLLHLTGYNLS
IEDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVS
HEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPQRFESYGWHVVPNVNGHDTAAIQAAIEAARAETGKPSIICC
KTLIGKGSANKEGSHKTHGAPLGADEIEATRKHLGWTYPAFEIPQEIYDAWNAKEKGAKLEAEWDKLFAQYQAKYPAEAA
EFVRRMDKKLPENFDGYVQTALKEVCAKAETVATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVSVTRDKGGN
YIHYGVREFGMGAIINGLVLHGGVKPFGATFLMFSEYERNALRMAALMKINPVFVFTHDSIGLGEDGPTHQPIEQTATLR
LIPNMDVWRPCDTAESLVAWAEAVKAADHPSCLIFSRQNLKFQARSEQQLNDIKRGGYVISEAQGNAQAVIIATGSEVEL
ALEAQKALAAQNIAVRVVSMPSTNVFDRQDTAYQAAVLPEGLPRIAVEAGHADGWYKYVGLNGAVVGINRFGESAPADLL
FKEFGFTVDNVVDTVKSVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 63
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 61