Gene Information

Name : hom (NMC1128)
Accession : YP_975166.2
Strain : Neisseria meningitidis FAM18
Genome accession: NC_008767
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 1105196 - 1106503 bp
Length : 1308 bp
Strand : +
Note : catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine

DNA sequence :
ATGAAGCCAGTAAACATCGGTCTTTTAGGTTTGGGTACGGTCGGCGGCGGTACGGCTGCCGTGTTGCGGGACAACGCGGA
GGAAATTTCCCGCCGCTTGGGGCGCGAAGTGCGCATCAGTGCCGTATGCGACTTGAGCGAAGAAAAAGCCCGCCAAATCT
GCCCGTCCGCAGCCTTTGTCAAAGATCCGTTCGAACTGGTCGCGCGTAAAGACGTCGATGTCGTCGTCGAATTGTTCGGC
GGCACGGGCATTGCCAAAGATGCGGTGTTGAAAGCCATTGAAAACGGCAAACACATCGTTACCGCCAACAAAAAACTGCT
CGCCGAATACGGCAACGAAATCTTCCCGCTGGCGGAAGAAAAAAATGTCATGGTGCAATTTGAAGCGGCAGTAGCGGGCG
GTATCCCAATCATCAAAGCCCTGCGCGAAGGTTTGGCGGCAAACAGGATTAAATCCATCGCCGGCATTATTAACGGCACC
AGCAACTTCATCCTCTCCGAAATGCGTGAAAAAGGCAGCGCGTTTGCCGATGTACTGAAAGAAGCGCAGGCACTGGGCTA
TGCCGAAGCCGACCCGACCTTCGACATCGAAGGACATGACGCGGGCCATAAAATCACCATCATGAGCGCGCTGGCATTCG
GCACGCCGATGAACTTTTCCGCCTGCTACCTCGAAGGCATCAGCAAACTCGACAGCCGCGACATCAAATACGCCGAAGAA
CTTGGCTACCGCATCAAACTGTTGGGCATCACCCGCAAAACCGGCAAAGGCATCGAGCTGCGCGTCCACCCTACCCTGAT
TCCCGAAAGCCGCCTCTTGGCAAACGTCAACGGCGTGATGAACGCCGTGCGCGTCAACGCCGATATGGTTGGCGAAACCT
TATATTACGGCGCGGGCGCGGGCGCATTGCCGACCGCTTCCGCCGTGGTTGCCGATATCATCGACATCGCCCGCCTGGTT
GAAGCCGATACCGCCCACCGCGTACCGCATCTGGCGTTCCAACCCGCGCAAGTCCAAGCGCAAACCATCCTGCCTATGGA
CGAAATTACCAGCAGCTACTACCTGCGCGTCCAAGCCAAAGACGAACCGGGCACGCTGGGGCAAATCGCCGCGCTGTTGG
CACAAGAAAACGTGTCCATCGAAGCACTGATTCAAAAAGGCGTGATTGATCAGACCACTGCCGAAATCGTGATTCTGACC
CACAGCACGGTCGAAAAACACATCAAGTCGGCAATCGCAGCCATCGAAGCACTGGATTGCGTGGAAAAACCGATTACCAT
GATCCGCATGGAAAGCCTGCATGACTGA

Protein sequence :
MKPVNIGLLGLGTVGGGTAAVLRDNAEEISRRLGREVRISAVCDLSEEKARQICPSAAFVKDPFELVARKDVDVVVELFG
GTGIAKDAVLKAIENGKHIVTANKKLLAEYGNEIFPLAEEKNVMVQFEAAVAGGIPIIKALREGLAANRIKSIAGIINGT
SNFILSEMREKGSAFADVLKEAQALGYAEADPTFDIEGHDAGHKITIMSALAFGTPMNFSACYLEGISKLDSRDIKYAEE
LGYRIKLLGITRKTGKGIELRVHPTLIPESRLLANVNGVMNAVRVNADMVGETLYYGAGAGALPTASAVVADIIDIARLV
EADTAHRVPHLAFQPAQVQAQTILPMDEITSSYYLRVQAKDEPGTLGQIAALLAQENVSIEALIQKGVIDQTTAEIVILT
HSTVEKHIKSAIAAIEALDCVEKPITMIRMESLHD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 5e-93 55
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 5e-93 55