Gene Information

Name : guaA (Aave_3367)
Accession : YP_971699.1
Strain : Acidovorax citrulli AAC00-1
Genome accession: NC_008752
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3723054 - 3724679 bp
Length : 1626 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAACACCAGAAGATCCTCATCCTCGACTTCGGCTCCCAGGTCACCCAGCTCATCGCGCGCCGCGTGCGCGAGGCCCA
TGTGTACTGCGAGGTGCATCCCTGCGACGTGAGCGACGCCTGGGTGCGCGAATACGCCGCCGACGGCTCGCTCAAGGGCG
TGATCCTCTCGGGCAGCCACGCCAGCGTGTACGAGGAGACCACCGACCGCGCGCCGCAGGCCGTGTTCGAACTGGGCGTG
CCCGTGCTGGGCATCTGCTATGGCATGCAGACCATGGCGCAGCAGCTCGGCGGCAAGGTCGAGGGCGGCCACAAGCGCGA
ATTCGGTTACGCCGAAGTGCGTGCCCACGGCCACACGGCGCTGCTGAAAGACATCGCCGACTTCACCACCGCCGAAGGCC
ACGGCATGCTCAAGGTCTGGATGAGCCATGGCGACAAGGTCGCCGAGATGCCGCCCGGCTTCAAACTCATGGCCTCCACG
CCCAGCTGCCCGATCGCCGGCATGGCCGACGAGGCGCGCCGCTTCTACGCCGTGCAGTTCCACCCGGAGGTGACGCACAC
CGTGCAGGGCCGCGCGCTGCTCGACCGCTTCGTGCTCGGCATCTGCGGCGTGCAGCCGGACTGGGTCATGAAGGACCACA
TCGCCGAGGCCGTGGAATCCATCCGCGCCCAGGTGGGCGACGAGGAAGTCATCCTCGGCCTCTCGGGTGGCGTGGATTCC
AGCGTGGCCGCCGCGCTCATCCACCGCGCCATCGGCGACCAGCTCACCTGCGTGTTCGTCGATCACGGCCTGCTGCGCCT
GAACGAGGGCGACATGGTGATGGACATGTTCGTGGGCAAGCTGCACGCCAAGGTCGTGCGGGTGGATGCGAGCGAGCTCT
TCCTGCGCGAACTGGCCGGCGTGAGCGACCCCGAGCAGAAGCGCAAGATCATCGGCCGCCTGTTCGTGGACGTCTTCAAG
GCCGAGGCCGCCAAGCTCACCGCCTCGGGCGCATCGAGGAAGGAGAAGGGCGCCACCTTCCTGGCCCAGGGCACCATCTA
CCCGGACGTGATCGAATCCGGCGGCGCCAAGAGCAAGAAGGCCGTCACCATCAAGAGCCACCACAACGTCGGCGGCCTGC
CGGAACAGCTCGGTCTCAAGCTGCTGGAGCCCCTGCGCGACCTGTTCAAGGACGAAGTGCGCGAACTGGGCGTGGCCCTC
GGCCTGCCGCACGACATGGTCTATCGCCATCCCTTCCCCGGCCCCGGCCTGGGCGTGCGCATCCTGGGTGAGGTGAAGAA
GGAATACGCCGACCTGCTGCGCCGCGCCGACGCGATCTTCATCGAGGAACTGCGCAACCACGTGGACGCCGAAACCGGCA
AGACCTGGTATGACCTCACCAGCCAGGCCTTCACCGTCTTCCTGCCCGTGAAGAGCGTCGGCGTGATGGGCGACGGCCGC
ACCTACGACTACGTCGTCGCCCTGCGCGCCGTGCAGACCAGCGATTTCATGACCGCCGACTGGGCCGAGCTGCCATACGC
GCTGCTCAAGAAGGTGTCGGGAAGGATCATCAATGAAGTCCGCGGGATCAACCGGGTGACGTACGACGTGTCGAGCAAGC
CGCCGGCGACGATCGAGTGGGAGTGA

Protein sequence :
MQHQKILILDFGSQVTQLIARRVREAHVYCEVHPCDVSDAWVREYAADGSLKGVILSGSHASVYEETTDRAPQAVFELGV
PVLGICYGMQTMAQQLGGKVEGGHKREFGYAEVRAHGHTALLKDIADFTTAEGHGMLKVWMSHGDKVAEMPPGFKLMAST
PSCPIAGMADEARRFYAVQFHPEVTHTVQGRALLDRFVLGICGVQPDWVMKDHIAEAVESIRAQVGDEEVILGLSGGVDS
SVAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMDMFVGKLHAKVVRVDASELFLRELAGVSDPEQKRKIIGRLFVDVFK
AEAAKLTASGASRKEKGATFLAQGTIYPDVIESGGAKSKKAVTIKSHHNVGGLPEQLGLKLLEPLRDLFKDEVRELGVAL
GLPHDMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRNHVDAETGKTWYDLTSQAFTVFLPVKSVGVMGDGR
TYDYVVALRAVQTSDFMTADWAELPYALLKKVSGRIINEVRGINRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-122 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-122 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-122 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-112 48