Gene Information

Name : thyA (Aave_1450)
Accession : YP_969815.1
Strain : Acidovorax citrulli AAC00-1
Genome accession: NC_008752
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1597018 - 1597857 bp
Length : 840 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAATGCCCCCGCCCGCCCCGTGCGCTCCCAGTACGAAGATTTCATGCGCCACGTCTATACCCATGGCGTGGCCAAGGG
CGACCGCACCGGCACCGGCACCCGCAGCGTGTTCGGCTACCAGATGCGGTTCGACCTGAACGAGGGCTTTCCACTGGTCA
CCACCAAGAAGGTCCACCTCAAATCCATCATCACGGAGCTGCTCTGGTTCCTCACCGGCTCCAGCAGCAACCACTGGCTG
AAGGAGCGCGGCGTCACCATCTGGGACGAATGGGCCCGCGAGGACGGCGACCTGGGGCCGGTCTACGGCGTGCAGTGGCG
CAGCTGGCCCACGCCGGACGGCGGCCATATCGACCAGATCAGCCAGGTGGTCGAAACGCTCAGGACCCATCCCGACTCGC
GCCGCATCATCGTCAGCGCCTGGAACGTGGCCGACCTGGACAAGATGGCCCTCATGCCCTGCCACGCGTTCTTCCAGTTC
TACGTGGCACCGCCGCAGGCCGCCGGAGAGCGGGGCAAACTGAGCTGCCAGTTGTACCAGCGCAGCGCCGACATCTTCCT
GGGAGTGCCCTTCAACATCGCGAGCTACGCGCTGCTGACCCACATGATGGCGCAGCAGTGCAATCTGGAGGTGGGCGATT
TCATCTGGACAGGCGGCGACTGCCACATCTACAGCAACCATTTCGAGCAGGTGGAGCTGCAGCTTTCTCGCGCCCCGCAC
CCCTATCCCACGCTGCACATCCTGCGCCGGCCGGACAGCCTCTTCGACTACCGTTTCGAGGATTTCGAAGTGCGCGACTA
CGCGCACCATCCCGCCATCAAGGCGCCGGTCGCGGTCTGA

Protein sequence :
MNAPARPVRSQYEDFMRHVYTHGVAKGDRTGTGTRSVFGYQMRFDLNEGFPLVTTKKVHLKSIITELLWFLTGSSSNHWL
KERGVTIWDEWAREDGDLGPVYGVQWRSWPTPDGGHIDQISQVVETLRTHPDSRRIIVSAWNVADLDKMALMPCHAFFQF
YVAPPQAAGERGKLSCQLYQRSADIFLGVPFNIASYALLTHMMAQQCNLEVGDFIWTGGDCHIYSNHFEQVELQLSRAPH
PYPTLHILRRPDSLFDYRFEDFEVRDYAHHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-88 65