Gene Information

Name : leuS (Dvul_1861)
Accession : YP_967305.1
Strain : Desulfovibrio vulgaris DP4
Genome accession: NC_008751
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2168089 - 2170578 bp
Length : 2490 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAAATACGATCATCAGTCCATCGAGACCCGGTGGCAGAAGAAGTGGGAAGACAGCGGCATCTTCCAGTGCGATACCGA
AGCCGACAAGCCCAAGTACTATGTGCTCGAGATGTTCCCCTACCCTTCGGGCAACATCCACATGGGGCACGTCCGCAACT
ATTCCATCGGCGACGTGGTGGCGCGCTTCAAGCGCATGCAGGGTTTCAACGTCCTGCACCCCATGGGATGGGACGCCTTC
GGCCTGCCCGCCGAGAACGCGGCCATCAAGAACGGCACCCACCCCGCCAAGTGGACGTTCGCCAACATCGACAACATGCG
CAGCCAGCTCAAACGCCTCGGCTACTCCTACGACTGGCAGCGCGAAGTGGCCACCTGCACACCCGAGTACTACAGGTGGG
AGCAGCTCTTCTTCTTGCGCTTCCTCGAGAAGGGTCTGGTCTACCGCAAGAAGGCTGCCCAGAACTGGTGCCCCAAGTGC
CACACCGTGCTCGCCAACGAGCAGGTCATCGAAGGACTGTGCTGGCGCTGTGACAGCGCGGTCGAGCAGAAGGAACTCAC
CCAGTGGTTCCTGCGCATCACCGACTATGCCGAAGAGCTTCTGGCCGACCTTTCCAAGCTCGAGAACGGCTGGCCCGAGC
GCGTCCTCAGCATGCAGCGCAACTGGATTGGCAAGTCGACGGGTGCAGAGATACGTTTCGCGCTGGACGGGCGCGACGAC
TCCATCACCGTCTTCACCACGCGCCCCGACACCATCTTCGGTGCCACCTTCATGAGCATCGCCCCCGAGCATCCGCTCGT
GGAAGAGCTCATCGACGGCAAGCCGCAAGCTGATGACGTGCGAGCCTTCGTCGAGCGCATCCGCAACATGGATCGCATCG
ACCGCCAGTCCGACACCCTCGAAAAGGAGGGCGTGTTCACCGGGGCCTACTGCGTGAACCCCTTCACCGGCCGAAAGATG
CCCATATGGGTGGCCAACTTCGTTCTCGCCGAATACGGAACCGGGGCTGTCATGGCCGTTCCCGCCCATGACCAGCGCGA
CTTCGAATTCGCCCGCAAGTACGACCTGCCCATGCAGGTGGTCATCCAGCCCCAGGGCGAAACGCTCGACCCCGCCACCA
TGTCTGCGGCATGGACCGAAGCCGGTGCGCTCGTCAATTCCGGCAACTTCGACGGACTCGCCAACGAAGACGCCAAGCAG
CGCATCGCCGACGACCTCGAGACTACCGGCAACGGACGCCGCACCATCAACTATCGTCTGCGCGACTGGAACATCTCGCG
TCAGCGGTACTGGGGCGCGCCCATCCCCGTCATCTACTGCGACGCCTGCGGCGTGGTGCCCGAGAAGGAAGAGAACCTTC
CCGTGGTGCTGCCGCTTGATGTGAAGACCCACGATGACGGTCGCTCGCCGCTGCCGCACACTCCGGCATTCTACGAGTGC
ACCTGCCCCGTATGCGGCGGCAAGGCACGGCGCGAGACGGACACCATGGACACCTTCGTCGAGTCGTCGTGGTACTTCGC
CCGGTACACCGACGCCACCAACGACAAGGCGCCCTTCACGCCCGACGCCCTGCGCTACTGGCTGCCCGTGGACCAGTACA
TCGGCGGTGTCGAACACGCCATCCTGCACCTGCTCTACTCCCGCTTCTTCACCAAGGCACTGCGCGACTGCGGCTTCATC
GAACTCGATGAACCCTTCGCCAACCTGCTCACGCAGGGCATGGTGCTCATGGATGGCAGCAAGATGTCCAAGTCGAAGGG
CAACGTCGTCGACCCCACGGAGATGATAGCCCGCTACGGCGCGGACACCGTGCGCCTCTTCTGCCTCTTCGCTGCACCGC
CGGAGCGCGACTTCGACTGGAGCGAGAGCGGCATCGAAGGTTCGTACCGCTTCGTGGGCCGTGTATGGCGTCTTGTCGAA
GAACTGCGCGAGCACCTTCTGGCTGTGGGCGCCTGTTCCAGCACCGCCGAGGACGCGAAGACACCCGTCGCGCGTGAACT
GCGGCTCAAGGAACATGCCACCGTCCGCAAGGCCGGTGACGACCTCAACGACAGGTTCCAGTTCAACACGGCCATCGCGG
CTGTCATGGAACTGGTCAACGCCCTGTATCTCGCCAAGGATGAACTCGTCGCAGACGAATCCGGTCGCAAGGTACTGTCT
TCCGCCGTGTCCACCGTGCTCACGCTGCTCTCTCCCTTCACGCCGCACCTTAGCGAGGAACTCTGGGCGCTTCTCGGGCA
CACCGAAAGCGTCAGCACCTTGCCGTGGCCGCGCTGGAAGGAAGATGCCCTCGTGCGCGATACGGTGACGCTGGTGGTGC
AGGTCAACGGCAAACTGCGCGGCAAGCTCGACATCCCCGCCGATGCGTCGCGCGAAGAGGTGGAGACCCTCGCCCTCAAC
GAACCCAACGTCCTCCGCTATCTGGAAGGCGTGACGGTGCGGAAGGTGGTGGTCATCCCCGGGAAACTCGTCAATGTGGT
CGTCAGTTAG

Protein sequence :
MKYDHQSIETRWQKKWEDSGIFQCDTEADKPKYYVLEMFPYPSGNIHMGHVRNYSIGDVVARFKRMQGFNVLHPMGWDAF
GLPAENAAIKNGTHPAKWTFANIDNMRSQLKRLGYSYDWQREVATCTPEYYRWEQLFFLRFLEKGLVYRKKAAQNWCPKC
HTVLANEQVIEGLCWRCDSAVEQKELTQWFLRITDYAEELLADLSKLENGWPERVLSMQRNWIGKSTGAEIRFALDGRDD
SITVFTTRPDTIFGATFMSIAPEHPLVEELIDGKPQADDVRAFVERIRNMDRIDRQSDTLEKEGVFTGAYCVNPFTGRKM
PIWVANFVLAEYGTGAVMAVPAHDQRDFEFARKYDLPMQVVIQPQGETLDPATMSAAWTEAGALVNSGNFDGLANEDAKQ
RIADDLETTGNGRRTINYRLRDWNISRQRYWGAPIPVIYCDACGVVPEKEENLPVVLPLDVKTHDDGRSPLPHTPAFYEC
TCPVCGGKARRETDTMDTFVESSWYFARYTDATNDKAPFTPDALRYWLPVDQYIGGVEHAILHLLYSRFFTKALRDCGFI
ELDEPFANLLTQGMVLMDGSKMSKSKGNVVDPTEMIARYGADTVRLFCLFAAPPERDFDWSESGIEGSYRFVGRVWRLVE
ELREHLLAVGACSSTAEDAKTPVARELRLKEHATVRKAGDDLNDRFQFNTAIAAVMELVNALYLAKDELVADESGRKVLS
SAVSTVLTLLSPFTPHLSEELWALLGHTESVSTLPWPRWKEDALVRDTVTLVVQVNGKLRGKLDIPADASREEVETLALN
EPNVLRYLEGVTVRKVVVIPGKLVNVVVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-159 42