Gene Information

Name : thyA (Sputw3181_3018)
Accession : YP_964389.1
Strain : Shewanella sp. W3-18-1
Genome accession: NC_008750
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3442006 - 3442800 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAACAGTATTTAGACTTAATGAAGCACATTTTAGCTGAGGGTGTGGATAAATCGGATCGTACCGGTACTGGAACTCG
TTCAGTATTTGGATATCAAATGCGTTTTGATTTAAGTAAAGGATTTCCCTTAGTAACGACTAAAAAATGCCATATGCGCT
CTATTATTCATGAGTTACTGTGGTTCCTGAAAGGTGAGACTAACATTGCTTACCTTCGTGAAAATAAAGTGAGTATTTGG
GATGAATGGGCCGATGATAATGGCGATTTAGGCCCGGTTTATGGCGCCCAATGGCGGAGCTGGCCAACTCAGAGTGGTGA
TGCTATTGACCAAATATCACAAGTTATCGCTCAGATTAAAGCTCAACCAGACTCTCGTCGTTTAATCGTTTCTGCATGGA
ATGTTGGTGAACTCGATAAAATGGCTTTAGCGCCTTGCCATGCTTTTTTTCAGTTCTATGTGGCTGATGGCAAGTTATCC
TGTCAGCTCTATCAACGCAGTTGTGATGTTTTCCTCGGCTTACCATTTAATATTGCTAGTTACGCACTACTAACGATGAT
GGTTGCCCAGCAGTGTGATTTAGCGCTTGGTGATTTTGTGTGGACAGGGGGGGATACGCATTTGTATTCCAATCATATGG
AACAAACAGTGCTGCAATTGAGCCGGGAACCCAAACCGTTACCTTTAATGACGATTCTGCGTAAACCTGAATCTATTTTC
GACTATCAATTCGAAGATTTTGAACTGACAAATTACAATCCTCATCCTCACATCAAAGCTCCTGTCGCCGTTTAG

Protein sequence :
MQQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVTTKKCHMRSIIHELLWFLKGETNIAYLRENKVSIW
DEWADDNGDLGPVYGAQWRSWPTQSGDAIDQISQVIAQIKAQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTVLQLSREPKPLPLMTILRKPESIF
DYQFEDFELTNYNPHPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-82 63