Gene Information

Name : guaA (Sputw3181_1362)
Accession : YP_962759.1
Strain : Shewanella sp. W3-18-1
Genome accession: NC_008750
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1543513 - 1545090 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCGATATTCATGAGCACAAGATACTGATCCTCGATTTTGGATCCCAGTACACTCAACTGATTGCCCGTCGTATCCG
TGAAATTGGCGTTTACTGCGAATTATGGGCATGGGATGTGACCGAAGCCCAAATCCGTGAGTTTGCCCCTAACGGTATTA
TCCTAGCGGGCGGCCCTGAAAGTGTGACGGCTGAAAATTCTCCCCGTGCACCTGAATATGTCTTTAACGCTGGCATACCT
GTTTTAGGTATTTGCTACGGCATGCAGACTATGTCTGAGCAGTTAGGTGGTAAAGTTATTCAAGGTGTGGGCGAAGGTGA
ATTTGGCTACGCTCAAATTGAAATGCTGACAAAATCTGCGCTGTTCAAAGATATTGAAGATGCAGTCAATAGCGAAGGGA
AACCTCTGCTCGATGTATGGATGAGCCACGGTGATAAAGTCTCTGCGATCCCTGAGGGATTTGTGGCGGTAGCTAAAACC
GATACTTGCCCATTTGCTGCTATGGCTAATGAAGAAAAACGCTTCTATGGCGTACAGTTCCACCCAGAAGTGACCCACAC
TCGTCAAGGCATGCGGATGTTATCGCATTTTGCCTTAGACATCTGTGGCTGTGCCGCCAACTGGAAACCCTCATCGATTA
TTGAAGATGCGATTGAGCGTTTGAAGAAGCAAATCGGCGATGATGAAGTGATTTTAGGCTTGTCTGGTGGTGTCGATTCT
TCGGTTGTAGCTATGTTGCTACACCGCGCGATTGGTAAAAAACTGACCTGCGTATTCGTTGATAACGGTTTATTGCGATT
GAATGAAGCTGCACAAGTGATGGAAATGTTTGGCGATCATTTCGGCCTGAATATCATCCACGTTGATGCGGAAAACCGTT
TCCTCGATGCGATGAAGGGCGTTGCAGATCCAGAAGCAAAACGCAAAATCATCGGCCGTGTATTTGTGGAAATTTTCGAT
GAAGAATCGAAAAAATGCGCCAATGCTAAATGGTTAGCCCAAGGGACTATCTACCCCGATGTGATTGAATCTGCTGGCAG
CGCCACAGGTAAAGCCCATGTGATTAAATCACACCATAACGTCGGCGGTTTGCCAGACGATATGGCGCTCGGCTTAGTTG
AGCCACTGCGTGAACTCTTTAAAGATGAAGTGCGCAAAATTGGTCTTGAGTTAGGTCTGCCTTACAATATGCTTTATCGT
CACCCGTTCCCAGGTCCAGGCTTAGGGGTGCGTGTACTCGGTGAAGTGAAGAAAGAATACTGTGACTTGTTGCGCCGCGC
CGATGCTATCTTCATCGAAGAACTGCATAAAGCCGACTTATACAATAAAGTCAGCCAAGCCTTTACCGTGTTCTTACCTG
TGCGCTCTGTTGGCGTGATGGGCGATGGCCGTAAATATGACTGGGTTGTATCACTGCGCGCAGTGGAAACCATCGATTTT
ATGACGGCACATTGGGCACATCTACCCTATGATTTCTTGGGGCGAGTGTCGAACCGCATCATCAACGAAGTCGATGGCAT
TTCCCGTGTGGTTTACGATATCTCTGGCAAGCCGCCAGCGACTATCGAGTGGGAATAA

Protein sequence :
MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFNAGIP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTKSALFKDIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKT
DTCPFAAMANEEKRFYGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDS
SVVAMLLHRAIGKKLTCVFVDNGLLRLNEAAQVMEMFGDHFGLNIIHVDAENRFLDAMKGVADPEAKRKIIGRVFVEIFD
EESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMALGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-125 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-125 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-125 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-110 47