Gene Information

Name : leuS (Sputw3181_1040)
Accession : YP_962444.1
Strain : Shewanella sp. W3-18-1
Genome accession: NC_008750
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1183280 - 1185859 bp
Length : 2580 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATATAATCCCTCAGAAATTGAAGCCTTAGTGCAAAAGCACTGGCATGACAACAAAACCTTCGAAGTCAC
TGAAGACGCAAACAAAGAAAAGTTTTATTGCCTTTCGATGTTTCCCTATCCTTCTGGCCGACTCCACATGGGACACGTTC
GCAACTATACCATAGGTGACGTCGTTGCGCGCTTCCAGCGTCTTCAAGGCAAAAATGTGCTGCAACCAATTGGTTGGGAC
TCCTTTGGTTTGCCTGCAGAAAATGCCGCGATTAATAATAAAACAGCACCTGCGCCATGGACCTATGAAAACATAGAGTA
CATGAAAAACCAGCTAAAACTGCTAGGTTTTGGTTACGATTGGAGCCGTGAAATCGCCACTTGTACCCCAGAATATTATC
GCTGGGAACAATGGTTCTTCACTAAGTTGTACGAGAAGGGCCTAGTCTATAAAAAGACCGCTTCCGTCAACTGGTGTCCA
AACGATGAAACCGTGCTGGCGAACGAGCAAGTACAAGACGGTTGCTGCTGGCGCTGTGATACCCCTGTGGAACAAAAAGA
AATTCCACAGTGGTTTATTAAGATCACTGCCTATGCAGAAGAATTATTAAACGATATCGATACCTTAGATGGCTGGCCAG
AACAGGTCAAAACCATGCAGCGTAACTGGATTGGTCGCAGTGAAGGCGTAGAAATGACCTTCGGCGTGGCAGGTCACGAT
AAAACCTTCGATATCTACACCACGCGTCCAGATACCTTAATGGGCGTGACCTATGTGGCGATTGCCGCAGGTCATCCATT
GGCAGAAATCGCCGCGCAAACGAATCCTGAGCTTGCCGCCTTTATCGATGAGTGCAAAAACAGCACAACATCTGAAGCCG
AACTCGCGACTATGGAAAAACGCGGTGTCGCTACAGGACTTTTCGCCATTCATCCCATCACTGGCAAGCAAGTGCCGATT
TGGGCCGCTAACTTTGTGCTGATGAACTATGGCACAGGTGCCGTAATGTCAGTTCCTGGGCACGACCAACGTGACTTTGA
ATTTGCAAAAAAATACGGCCTAGCGATTGAAGCTGTGATCAAGCCTGTTGATGGCGAAGTCGATATCAGTGAAGCCGCTT
ACACCGAAAAAGGCATTCTGTTTAACTCTGGCGAGTTCGACGGTTTAGACTTTGACGCCGCCTTTAATGCCATCGCTAAC
AAGTTAGTGGCAGAAGGTAAAGGCAAGCGCCAAGTCAACTATCGTCTACGCGATTGGGGTGTTTCACGTCAGCGTTACTG
GGGCGCACCAATCCCTATGGTGACCTTAGCTGACGGCACTGTGATCCCAACACCTGAAGATCAACTGCCAGTATTGCTGC
CAGAAGATGTGGTGATGGACGGGATTCAAAGCCCAATCAAAGCCGATAAAGAATGGGCCAAAACCCAAGTGAACGGTCAA
GATGCACTGCGCGAAACCGATACCTTCGATACCTTTATGGAATCCTCTTGGTATTATGCCCGTTACTGCAGCCCGCAGGC
AGACGAAATGTTAGATCCCGCTAAAGCCAACTACTGGCTACCCGTAGATCAATACATTGGTGGTATCGAACACGCTTGTA
TGCATTTGTTATATTTCCGCTTCTTCCACAAGTTGCTGCGTGATGCGGGTCTGGTTAACTCTAACGAGCCAGCCAAACAA
TTGCTGACTCAGGGCATGGTGTTGGCTGATGCTTTCTACTACATCAACGAAAAAGGCGCCCGTGTGTGGGTTTCTCCTTT
AGATGTAGCGACCACCGAAAAAGACGACAAGGGCCGTATCACTAAGGCTATAGACAAAGACGGCAACGAACTGGTTTACA
CTGGTATGTGCAAGATGTCTAAGTCGAAAAACAACGGTATCGACCCGCAGGTGATGGTTGAAAAATATGGCGCAGACACT
GTGCGTCTATTTATGATGTTCGCCTCACCGCCAGAATTAACCCTGGAATGGCAAGAGTCTGGCGTTGAAGGCGCACACCG
CTTCATTAAACGTCTGTGGAAGCTTGCAAGCGAGTATATCGCCCAAGATAACAGTGAAGCCTTAGATGTCAGCAAGTTAA
CAAGCGAGCAAAAAGCGCTGCGCCGTGAAGTCCACAAAACCATTGCCAAAGTGACCGACGATATCGGCCGCCGTCAAATG
TTCAACACTGCGGTTGCCGCCGTAATGGAACTGATGAACCACCTGCAAAAAGCGCCACAAACCACAGGCCAAGACAGAGC
CATTATCGGTGAAGCCTTATCTGCGGTCGTGCGTTTACTGTACCCCATTATTCCACATGTGAGCTTTACCTTGTGGAATG
ACTTAGGTAATACAGGCAGCATCGAAGACAGCCAATGGCCGGTTGTTGATGAATCTGCCTTGGTAGAAGACAGTAAACTG
ATTGTGGTACAAGTGAACGGTAAAGTTCGCGCTAAAATCACTGTTGCCGCCGATGCGGATAAAGACTCAGTTGAAGCCTT
GGGTATGAATGATGAGCATGTGATCAAATACCTAGATGGCCTGACAGTACGTAAAGTGATCTATGTACCAGGTAAACTGC
TCAGCATAGTGGCAAATTAA

Protein sequence :
MQEQYNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARFQRLQGKNVLQPIGWD
SFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCP
NDETVLANEQVQDGCCWRCDTPVEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGHD
KTFDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELATMEKRGVATGLFAIHPITGKQVPI
WAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEAVIKPVDGEVDISEAAYTEKGILFNSGEFDGLDFDAAFNAIAN
KLVAEGKGKRQVNYRLRDWGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVLLPEDVVMDGIQSPIKADKEWAKTQVNGQ
DALRETDTFDTFMESSWYYARYCSPQADEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDAGLVNSNEPAKQ
LLTQGMVLADAFYYINEKGARVWVSPLDVATTEKDDKGRITKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADT
VRLFMMFASPPELTLEWQESGVEGAHRFIKRLWKLASEYIAQDNSEALDVSKLTSEQKALRREVHKTIAKVTDDIGRRQM
FNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAVVRLLYPIIPHVSFTLWNDLGNTGSIEDSQWPVVDESALVEDSKL
IVVQVNGKVRAKITVAADADKDSVEALGMNDEHVIKYLDGLTVRKVIYVPGKLLSIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-161 43