Gene Information

Name : hemC (Maqu_0487)
Accession : YP_957775.1
Strain : Marinobacter aquaeolei VT8
Genome accession: NC_008740
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 551667 - 552608 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCCAAACGTACCCTTCGCATTGCAACCCGCAGCAGCGCACTGGCGCTGTGGCAGGCGGAATTCATCAAGGCCGAGCT
GGAAAGGCTGCATGACAACGTTGACGTTGAACTGATCAAGATCAAGACCCAGGGCGACAAGATCCTGGACGTCCCCCTGG
CCAAGATCGGCGGCAAGGGCCTGTTCGTGAAGGAGCTCGAAGAAGCCATGCTGGACGGCCGTGCCGATCTGGCCGTGCAT
TCCATGAAAGACGTGCCCATGGAATTCCCCGAAGGCCTGGGGCTGGTCGCCATTTGCGAGCGTGAAGACCCCACCGATGC
CTTCGTCAGCAATCAGTATGAACACATCGACCAGCTGCCTGAGGGCGCGGTAGTAGGCACCGCCAGCCTGCGTCGGGAAG
CCCAGCTGCGGGCCAACCGCCCGGATCTTCAGATCAAGGTACTGCGTGGCAACGTGAATACCCGGTTGGCGAAACTCGAT
GCCGGTGAATACGACGCCATTGTACTGGCCAGCTCCGGCCTGAAGCGTCTCGGCTTCCACGACCGTATCCGTTACTGTCT
GCCAGACACGTTTTCCCTGCCAGCCGTTGGCCAGGGTGCTTTGGGCATCGAATGCCGGGTCGGTGACACGGAACTTCTGG
AGCTGATTGACCCGCTCAATCACACCGACACCTGGGACCGCGTCAGCGCTGAGCGGGCGCTGAACCGTCGCCTTGAAGGC
GGTTGCCAGGTGCCCATTGCCGCCTATGCCCTGCTGGAAGACGATAACACCCTGTGGCTGCGGGGCCTGGTTGGCGCAGT
CGATGGTACCCAGATTTTCCGGGTGGAAGGCCGTGCCCCGCGCGCCGAAGGTGAACGCCTGGGCCGTGAACTGGCAGAAC
AGCTGCTGTCCATGGGGGCCGACAAGGTGCTGGCTGAAATCTATGGCCACACCCCACGCTGA

Protein sequence :
MSKRTLRIATRSSALALWQAEFIKAELERLHDNVDVELIKIKTQGDKILDVPLAKIGGKGLFVKELEEAMLDGRADLAVH
SMKDVPMEFPEGLGLVAICEREDPTDAFVSNQYEHIDQLPEGAVVGTASLRREAQLRANRPDLQIKVLRGNVNTRLAKLD
AGEYDAIVLASSGLKRLGFHDRIRYCLPDTFSLPAVGQGALGIECRVGDTELLELIDPLNHTDTWDRVSAERALNRRLEG
GCQVPIAAYALLEDDNTLWLRGLVGAVDGTQIFRVEGRAPRAEGERLGRELAEQLLSMGADKVLAEIYGHTPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-87 64
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-87 64