Gene Information

Name : Maqu_3853 (Maqu_3853)
Accession : YP_961108.1
Strain : Marinobacter aquaeolei VT8
Genome accession: NC_008740
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 4273216 - 4274226 bp
Length : 1011 bp
Strand : -
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: ana:alr0058 D-lactate dehydrogenase

DNA sequence :
ATGAAAGTGGCGGTTTTCAGCACCAAGCCCTATGACGAACAGTTCCTGGCACAGGCGAACCAGGCCAGCCACCAGCATGA
ACTGGTGTTCCTGGAACCACGCCTGAATGCGGCCACTGCGGCACTGGCCAAAGGCTTCGACGCGGTATGCGTGTTCGTGA
ACGACCAGGTGGACGCCAACGTTCTGGAACAGCTGGCCGCCGGCGGCACCCGGGCCGTGGCCCTGCGCTGCGCCGGGTTC
AACAACGTCGACCTGAAAGCCGCCGAACGCCTGGGCATCGCCGTGGTGCGGGTACCGGCGTATTCCCCCTATGCGGTGGC
CGAACACACCGCCGCCTTGATCCTCACCCTGAACCGGCAGATCCACCGGGCCTACCACCGCATTCGTGATGGCAACTTTG
CCCTCGACGGCCTGCTGGGGTTCGATCTGCGGGGCCGCACCGTGGGTGTGGTGGGCACTGGCCAGATTGGCGTGGAAGTG
GTGCGCATCATGCGCGGTTTCGGCTGCCGCGTGCTGTGCTACGACCTGCACGCCAACCCGGAGGCGCAAACGCTGGGCGC
GGAATATGTGAGCCTGGACGAACTGTTCCGGAAAGCAGACATTGTGACCCTGCATTGCCCGCTCACCCCGGACACCCATC
ACCTGATTGATGCCGCAGCCGTGGCCAAAATGAAAAAAGGCGTGATGCTGATCAACACCAGCCGGGGCGCCATGGTGGAC
ACCGCCGCCATCATCGAAGGCCTGAAATCCGGCCAGGTGGGCTACCTGGGGCTGGATGTGTATGAGGAAGAAAGCGACCT
GTTCTTCGAAGATCTCTCCAATATCGTGCTGAAAGACGACGTGTTCGCCCGTTTGCTCACATTTCCGAATGTAGTCATCA
CCGGCCACCAGGCGTTTTTCACCCGCAACGCCCTGGAAAGCATTGCACACACAACACTCAGCAACCTGACGGACCTGGAA
ACCGGCGGCGAATGCGCAAACCGGGTGCTGGCCGCCAACGGCAGCACCTGA

Protein sequence :
MKVAVFSTKPYDEQFLAQANQASHQHELVFLEPRLNAATAALAKGFDAVCVFVNDQVDANVLEQLAAGGTRAVALRCAGF
NNVDLKAAERLGIAVVRVPAYSPYAVAEHTAALILTLNRQIHRAYHRIRDGNFALDGLLGFDLRGRTVGVVGTGQIGVEV
VRIMRGFGCRVLCYDLHANPEAQTLGAEYVSLDELFRKADIVTLHCPLTPDTHHLIDAAAVAKMKKGVMLINTSRGAMVD
TAAIIEGLKSGQVGYLGLDVYEEESDLFFEDLSNIVLKDDVFARLLTFPNVVITGHQAFFTRNALESIAHTTLSNLTDLE
TGGECANRVLAANGST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 9e-30 43
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-30 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Maqu_3853 YP_961108.1 D-isomer specific 2-hydroxyacid dehydrogenase U35369.1.gene5.p01 Protein 4e-30 43
Maqu_3853 YP_961108.1 D-isomer specific 2-hydroxyacid dehydrogenase AF310956.2.orf4.gene Protein 1e-30 42
Maqu_3853 YP_961108.1 D-isomer specific 2-hydroxyacid dehydrogenase AF155139.2.orf4.gene Protein 1e-27 41