Gene Information

Name : Maqu_3386 (Maqu_3386)
Accession : YP_960644.1
Strain : Marinobacter aquaeolei VT8
Genome accession: NC_008740
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 3743900 - 3747058 bp
Length : 3159 bp
Strand : +
Note : KEGG: noc:Noc_1804 type I site-specific deoxyribonuclease HsdR; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like

DNA sequence :
GTGACTGAGGATCAGCTGGAACAACAATGCCTGCAATGGTTCGCCGAAGGCGGCTGGGAGATCGCCCACGGGCCCGATCT
GGCATCGGACGGAGAGGCCCCGGAACGGGCCGATTACCGGCAGGTCTTGTTGCTGGCGGATCTTGAGGCAGCGATACAGC
GCATCAACCCTCACCTGCCCCAAAGCGCTGTTGAACAAGCCGTGGCCGTGGTGCGCAAACCCGAAAGCCTGGACGTGGTG
ATCAGCAACCGGGCCTTTCACCGCCTGCTGCTGGACGGTGTGCCGGTGGAGTACAAGCGCGACGACAAGGTGGTTCACGA
CCAGGCCTTTCTAGTGGATTTTGGTGACCTCACCGCCAACCGGTTCCGGGCCATTAACCAGTTCACCATTGAGGGCTCCA
AACAGCTCCGCCGGCCGGATGTGATTTGCTTTATCAACGGCCTGCCACTGGCCGTGCTGGAGCTGAAAAGCCCGGGCGCA
GAGAACGTGAACATCTGGGATGCCTACAACCAGGTCCAGACCTATAAAGATGAATGCTCCGATCTTTTTGCCTACAACGA
AGCCGCCGTTATCAGCGATGGCTATCTGGCCCGGGTTGGCTCCCTCACCGCCAGCCAGGAGCGCTACATGCCCTGGCGCA
CCCTCAGGCACGAGGATGACAAGCCGTTGCTGGAATGGCAGCTGGAAACCATGGTGCGGGGCTTCTTCGACCGGGAGCTG
TTCCTGGATTACATCCGCTATTTTGTGATCTTCGAGACGGATTCCGACAAGCTGATCAAGAAGATTGCCGGATACCACCA
GTTCCATGCGGTGTGTGAAGCGGTAAAGGCCACGGTGATTGCCGCCCAGGCACCGGAGCACGGGCATTGGGCCAAGGAGA
AGCGCGCCACCTACGGCGATGAGGTTTTGCCCGGCAGCAAGAAAGCCGGCGTGGTATGGCACACCCAGGGCTCCGGCAAG
AGCATTTCCATGTGCTGTTACGCCGGCAAGCTGCTGCAACAGCCGGAGATGAACAACCCCACGCTGATTGTGGTCACCGA
CCGCAACGACCTGGACGGCCAGTTGTTTGCCACCTTCAGCGCCGTCCGGGAATTGCTGAAGCAGGAACCGGTGCAGGCCG
ATGACCGCGACACCCTGCGTCGGCTGCTGTCGGAACGGGAATCCGGCGGCATCATCTTCACCACGGTTCAGAAGTTCGCC
CTGCTCAACGATGAGTCCGGCCACCCGATTCTGAACGACCGCCACAACATCGTGGTGATCTCAGACGAAGCCCACCGCAG
CCAGTACGGCCTGAAAGCCACCCTCAAGAAGGACGGCACCTACAAGTTCGGCTACGCCCGCCACATGCGCGATGCCCTGC
CCAATGCCTCGTTCATCGGCTTTACCGGCACCCCCATCGAGAGCGAAGACAAAGACACCCGGGCCGTGTTCGGCGATTAC
GTGTCGATCTACGACATCCAGGATGCCGTGGACGATGGTGCGACCGTGCCCATCTTCTACGAATCCCGCCTGGCCAAACT
CGACATCAACCGCGAACAGATCGAGGAATTGTCGGATCAGGTGGAGGAAGTGGTTGAAGACGACGAAGACGTTGGCAGCC
GCGAGAAAACCAAGGGCGAGTGGAGCCGGCTGGAGAAGCTGGTCGGCGCCGGCCCGCGCCTGAAGCAGGTGGCGGAAGAC
CTGGTAAACCACTTTGAAACCCGCTCCAGCACCATAGACGGCAAGGCCATGATTGTGGCCATGAGCCGGGAGATTGCGGT
TCACCTGTATAACGAGATTGTCGCCCTGCGCCCGGAATGGCACGACGATGATCCCGAGAAAGGCGCCATCAAGATCGTGA
TGACCGGCTCCGCCTCTGATCGCGCGCTGCTGCAGCCGCACATCCACAACAAGCAGACCAAGAAACGGTTCGAGAAGCGC
TTCAAAGACATCAACGACCCGCTCAGGCTGGTGATCGTGCGGGATATGTGGCTGACCGGCTTCGATGCGCCCTGCTGTCA
CACCATGTATGTGGACAAGCCCATGAAGGGCCACAACCTGATGCAGGCCATTGCCCGCGTAAACCGCGTGTTCAAGGACA
AGCCCGGCGGGCTGGTGGTGGATTACATCGGCATCGCCAACGAGCTCAAGCAGGCCCTGAAAACCTACACCGACGCTAAG
GGCAAGGGCTCACCTACCCATAGCGCAGAAGAAGCCTACGCCATCCTGCTGGAGAAGCTGGACATCATCCACGGCATGTT
TGCCCCCGGCCCCAAAGGTAAGGGCTTCAGCTATAGCGGTTTTGACACCGAGCCCCGCAAGGTTCTGCTGGCCACCGCGA
ACTATGTGCTCAGCCTGGAAGACGGCAAAAAGCGCTTCTTGGATACCGTGCTGGCCATGAACAAAGCCTTCTCCCTGTGC
GCCACCCTGGACGAAGCCCAAACGCTTCAGAAGGAGGTGGCGTTCCTGTCGCAGGTGAAGACGGCCATCACCAAGTTCAC
CAGCGTAGACAAGAAGCTGACTGAGGAAGAGAAGAACACGGCGCTGCGGCAGATCCTGAACAACGCTCTCATCGCCGAAG
GGGTTACCGATGTCTTCGCCCTGTGCGGCCTGGACAAGCCCAACATCGGCCTGCTCTCTGACGAGTTCCTGGAAGACGTT
CGGCAAATGCCCTACAAGAACTTCGCCGTGGAACTCCTGGAGAAGCTGCTCAAGGACGACATCAAGGCCAAGACCCGCAA
CAACGTAGTACAGGAGAAGAAGTACGCCGACCGCCTGCAGGAGACGCTGCGCAAGTACAACAACCGGGGCATCGAGACAG
CCCAGGTGATCGAAGAGCTGATCGCCATGGCCAAGCAGTTCCAGGCTGAAATGGAGCGGGATGCCGCCCTCGGTCTGAAC
CCGGACGAAGTGGCCTTCTACGACGCCCTGGCCAGCAATGAAAGCGCCGTGCGGGAGCTGGGCGACGAGATCCTGAAGAA
GATCGCCGTGGAGATCACCGACAAGCTGCGCAAATCCACCACCGTGGACTGGCAGGTACGGGAGAGCGTGCGGGCCAAGC
TTAGGATTCTGGTGCGGCGGACGTTGCAGCGGTACAAGTACCCGCCAGACAAGGCGCCAGCGGCGATTGAGTTGATTATG
GAGCAGGCGGAAGCCTTATCTAACCACTGGACAAGGTGA

Protein sequence :
MTEDQLEQQCLQWFAEGGWEIAHGPDLASDGEAPERADYRQVLLLADLEAAIQRINPHLPQSAVEQAVAVVRKPESLDVV
ISNRAFHRLLLDGVPVEYKRDDKVVHDQAFLVDFGDLTANRFRAINQFTIEGSKQLRRPDVICFINGLPLAVLELKSPGA
ENVNIWDAYNQVQTYKDECSDLFAYNEAAVISDGYLARVGSLTASQERYMPWRTLRHEDDKPLLEWQLETMVRGFFDREL
FLDYIRYFVIFETDSDKLIKKIAGYHQFHAVCEAVKATVIAAQAPEHGHWAKEKRATYGDEVLPGSKKAGVVWHTQGSGK
SISMCCYAGKLLQQPEMNNPTLIVVTDRNDLDGQLFATFSAVRELLKQEPVQADDRDTLRRLLSERESGGIIFTTVQKFA
LLNDESGHPILNDRHNIVVISDEAHRSQYGLKATLKKDGTYKFGYARHMRDALPNASFIGFTGTPIESEDKDTRAVFGDY
VSIYDIQDAVDDGATVPIFYESRLAKLDINREQIEELSDQVEEVVEDDEDVGSREKTKGEWSRLEKLVGAGPRLKQVAED
LVNHFETRSSTIDGKAMIVAMSREIAVHLYNEIVALRPEWHDDDPEKGAIKIVMTGSASDRALLQPHIHNKQTKKRFEKR
FKDINDPLRLVIVRDMWLTGFDAPCCHTMYVDKPMKGHNLMQAIARVNRVFKDKPGGLVVDYIGIANELKQALKTYTDAK
GKGSPTHSAEEAYAILLEKLDIIHGMFAPGPKGKGFSYSGFDTEPRKVLLATANYVLSLEDGKKRFLDTVLAMNKAFSLC
ATLDEAQTLQKEVAFLSQVKTAITKFTSVDKKLTEEEKNTALRQILNNALIAEGVTDVFALCGLDKPNIGLLSDEFLEDV
RQMPYKNFAVELLEKLLKDDIKAKTRNNVVQEKKYADRLQETLRKYNNRGIETAQVIEELIAMAKQFQAEMERDAALGLN
PDEVAFYDALASNESAVRELGDEILKKIAVEITDKLRKSTTVDWQVRESVRAKLRILVRRTLQRYKYPPDKAPAAIELIM
EQAEALSNHWTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 71
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 44
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 44
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 44