Gene Information

Name : leuS (Maqu_2744)
Accession : YP_960006.1
Strain : Marinobacter aquaeolei VT8
Genome accession: NC_008740
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3070209 - 3072803 bp
Length : 2595 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCAGGAATGGACGAACAATACAACCCACGTGAAGTAGAACAGACCGCCCGCACTTTCTGGGAAACCAACGAGACCTT
CAAGGTCAAGGAAGAGCCGGGCAAGCCCAAGTACTACTGTCTGTCCATGTTCCCCTACCCCAGCGGCAAGCTGCATATGG
GCCACGTCCGCAACTACACCATCGGCGACGTGATCTCCCGTTACCAGCGCATGCAGGGCAAGAACGTGATGCAGCCCATG
GGCTGGGACGCCTTCGGCCTGCCTGCGGAAAATGCCGCCATTGCCAACAAGTCTGCACCGGCCAAGTGGACTCGCTCCAA
CATTGATTACATGAAGAACCAGCTCAAGCAGCTGGGGTTTGGCTACGACTGGAGCCGCGAACTGGCCACCTGCGACCCGG
AATACTACCGCTGGGAGCAGTGGTTCTTTGCCCGCCTGTACGAGAAAGGGCTGGTGTACAAGAAGATGTCCACCGTGAAC
TGGGACCCGGTTGACCAGACCGTATTGGCCAACGAGCAGGTGGTTGACGGTCGGGGCTGGCGCTCCGGTGCGCTGGTCGA
GCAGAAAAAGATTCCTCAGTGGTTCATTCGCATTACCGACTACGCAGAAGAGCTGCTGAACGATCTGGAAGACATGGAAG
GCTGGCCCGAGCAGGTCAAGACCATGCAGCGCAACTGGATCGGCAAATCGGTGGGTACCGAGCTGACCTTCCCACTGAAA
GAGCAGGAAGGTGGTCTGACGGTTTACACCACCCGCCCGGACACGCTGATGGGCGTCAGCTACATGGCGGTCGCCGCTGA
GCATCCGCTAGCCAAGGCGGCGGCCGAGCGCCACCGCGATGTGGCCGAGTTTGTCGACCAGTGCCGTAACAGCAAGGTGG
CCGAAGCCGAGCTGGCGACCATGGAAAAGAAAGGTATAGATACCGGCTTCAAGGCCATTCACCCGCTGACCCAGGAAGAA
ATCCCGGTCTGGGTCGCCAATTTCGTGCTCATGGATTACGGCACCGGCGCCCTGATGGCAGTTCCCGGCCATGATGAGCG
GGACCACGAGTTCGCCGTCAAGTACAAGCTGCCCATCAAGCAGGTGATCGCGCCGAACGACAGCCGCGATATCGATATCC
AGGAACAGGCGTTCACCGAGAAAGGTGTTCTGGTGTCTTCCGGCAAATACAGCGGCCTGACCAGCGAAGAAGCTTTTGAG
GAAATCGCGGATTATCTTGAAGCCCAGGGCATTGGCAAACGTACCGTGAACTACCGTCTGCGCGACTGGGGTGTGTCCCG
TCAGCGCTACTGGGGTGCGCCCATCCCGATGATGACGCTGGAAGACGGCACCGAGATGCCGGTACCGGACGACCAGCTGC
CGGTTCGTCTGCCCGAAGACGTTGAAATGGACGGCGTCCAGTCGCCAATCAAGGCCGACCCGGAGTGGTGCAAGACCGAA
TACAACGGCCAGCCAGCCACCCTGGAAACCGATACCTTCGATACCTTCATGGAGTCCTCCTGGTATTACGCTCGTTTCTG
TAGCCCGAACTACGACAAGGGCATGCTGGACCCGGCCGCCGCCAATTACTGGCTGCCAGTCGACCAGTACATCGGCGGCA
TTGAGCACGCGATTCTGCACCTGCTGTATGCCCGGTTCTTCCACAAGCTGCTGCGTGACGTTGGTCTGGTGAACAGTTCC
GAGCCATTCAAGCGCCTGCTGACCCAGGGCATGGTTCTGGCCGAGACCTACTACCGCAATGAAGCGAATGGCGGGAAAAC
CTGGTACAACCCGGCCGATGTGACGGTTGAGCGCGATGGCAAAGGCCAGGTGGTGCGGGCCGTCCTGAAATCGGACGGCG
AGCCGGTGGAAATCGGTGGCGTTACCAAGATGTCCAAGTCCAAGAACAACGGTATTGATCCTCAGGCCATCATCGATCAG
CACGGTGCCGACACCGTGCGGCTGTTCATGATGTTTGCGGCACCCCCTGAGCAGTCGCTGGAGTGGTCCGACAGCGGCGT
TGAAGGTGCCCATCGCTTCCTCAAACGCCTGTGGCGGATGGTCAATGAGCATACCGCCGGTGGCGACGCTCCGGCGGTTG
ATCCTGCCAACCTCAACGGGGCCCAGAAAGACCTTCGGCGCAAGACCCATGAAACCATTGCCAAGGTCAGCGATGACATC
AGCCGCCGCCTGACCTTCAATACCGCCATTGCCGCGGTGATGGAGCTGCTCAATGAGGTCGGCCGCCTCAGTGATGACGA
GCCCCAGAGCCGAGCGGTTCGCCAGGAAGCCCTGGATACCGCAGTACTGGTGCTGTCACCCATTGTCCCGCACATCTGTC
ACAACCTTTGGCAGGCCCTGGGGCACTCCGACGCGGTGGTCGACGCCTCCTGGCCGGTTGCCGATGAAAGCGCCATGGTT
CGCAGCGAAATCGAGGTGGTTCTGCAGGTGAACGGCAAGGTCCGGGCCAAGGAGAATGTACCGGCGGATATTGGCAAAGC
AGATCTGGAGAAGCTTGCCCTGGAGAACGAAAACGTCATGCGCTTCACCGACGGCAAGACGGTGCGCAAAGTGATCGTTG
TGCCCGGAAAACTCGTGAACGTGGTGGCCAACTAA

Protein sequence :
MAGMDEQYNPREVEQTARTFWETNETFKVKEEPGKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVISRYQRMQGKNVMQPM
GWDAFGLPAENAAIANKSAPAKWTRSNIDYMKNQLKQLGFGYDWSRELATCDPEYYRWEQWFFARLYEKGLVYKKMSTVN
WDPVDQTVLANEQVVDGRGWRSGALVEQKKIPQWFIRITDYAEELLNDLEDMEGWPEQVKTMQRNWIGKSVGTELTFPLK
EQEGGLTVYTTRPDTLMGVSYMAVAAEHPLAKAAAERHRDVAEFVDQCRNSKVAEAELATMEKKGIDTGFKAIHPLTQEE
IPVWVANFVLMDYGTGALMAVPGHDERDHEFAVKYKLPIKQVIAPNDSRDIDIQEQAFTEKGVLVSSGKYSGLTSEEAFE
EIADYLEAQGIGKRTVNYRLRDWGVSRQRYWGAPIPMMTLEDGTEMPVPDDQLPVRLPEDVEMDGVQSPIKADPEWCKTE
YNGQPATLETDTFDTFMESSWYYARFCSPNYDKGMLDPAAANYWLPVDQYIGGIEHAILHLLYARFFHKLLRDVGLVNSS
EPFKRLLTQGMVLAETYYRNEANGGKTWYNPADVTVERDGKGQVVRAVLKSDGEPVEIGGVTKMSKSKNNGIDPQAIIDQ
HGADTVRLFMMFAAPPEQSLEWSDSGVEGAHRFLKRLWRMVNEHTAGGDAPAVDPANLNGAQKDLRRKTHETIAKVSDDI
SRRLTFNTAIAAVMELLNEVGRLSDDEPQSRAVRQEALDTAVLVLSPIVPHICHNLWQALGHSDAVVDASWPVADESAMV
RSEIEVVLQVNGKVRAKENVPADIGKADLEKLALENENVMRFTDGKTVRKVIVVPGKLVNVVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-160 42