Gene Information

Name : Maqu_0242 (Maqu_0242)
Accession : YP_957535.1
Strain : Marinobacter aquaeolei VT8
Genome accession: NC_008740
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 281898 - 283301 bp
Length : 1404 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: ilo:IL1646 mercuric ion reductase

DNA sequence : 
ATGAGTGACAACAACCTGCACATTGCGGTGATTGGCAGCGGTGGCAGTGCCATGGCTGCGGCCCTGAAAGCGACGGAGCG
CGGTGCCCGGGTGACGCTGATTGAGCGCGGCACCATCGGCGGAACCTGCGTCAACATTGGTTGCGTACCGTCCAAAATCA
TGATCCGGTCGGCGCATATCGCCCACCTTCGCCGGGAAAGCCCGTTTGACGACGGACTGAGTGCCCAGGCACCGGTGGTG
GATCGTTCAGCCCTTCTGGCTCAGCAACAGGCCCGGGTGGAGGAGCTGCGCGAGTCCAAGTACCAGAGCATTCTCAATGA
CAATGCCGCGATTACCGTCCTCAAGGGCGAGGCGCGGTTCGTGGACGAGCGCACACTGACGGTTACGCTCAACGACGGCG
GCGAGCAGACGGTGCACTTCGACCGGGCCTTTATCGGCACCGGTGCCCGGCCCGCCGAACCGCCTGTTCCGGGGCTATCC
GAGACGCCCTATCTCACGTCCACCAGTGCGCTGGAGCTGGATCACATTCCCGAGCGCCTCGTTGTGATTGGTGCCTCGGT
GGTGGCCATCGAGCTGGCTCAGGCCTTTGCCCGCCTTGGCAGTCGGGTCACCATTCTGGCCCGCAGCCGGGTGCTGTCTC
AGGAAGACCCGGCGGTGGGTGAAGCCGTGGAAGCGGCCTTCCGTCGCGAGGGCATCGAGGTGCTCAAGCAGACCCAGGCC
AGTGAGATTACCCACAATGGCCGGGTGTTCACCCTCCAAACCAACGCCGGCACCCTGGAGGCGGAGCAACTGCTGGTGGC
CAGTGGCCGCACACCCAATACCGAGAACCTGAACCTGGAGGCCGTCGGCGTGGCTACCGAGCGCGGCGCGATCCGGATCG
ACAACCACCTGCAAACGACCGCGTCCGGCATTTATGCAGCCGGGGACTGCACCGATCAACCCCAGTTCGTCTACGTGGCT
GCCGCCGGTGGTAGTCGGGCCGCCATTAACATGACCGGCGGTGACGCCAGCCTCGACCTCAGCGCCATGCCCGAGGTGAT
CTTTACCGATCCACAAGTGGCCACCGTCGGTCTGTCCGAGGCGGAGGCCCAGGCTCAGGGATACGACACCGACAGCCGCA
CCCTGACCCTCGATAACGTGCCCCGGGCCCTGGTTAACTTCGATACCGGGGGCTTCATCAAGATGGTCGCTGAGCGTGGC
AGCGGACGATTGCTGGGTGTCCAGTCCGTCGCGGGCGAAGCCGGTGAGCTGATCCAGACGGCCGTCATGGCGCTGCGTGC
GCGTATGACCGTGAACGACATTGCCGATGAGCTGTTCCCGTACCTGACCATGGTGGAGGGGCTCAAGCTCTGTGCCCAAA
CCTTCACCAAGGACGTGAAGCAATTGTCGTGCTGTGCGGGATAA

Protein sequence : 
MSDNNLHIAVIGSGGSAMAAALKATERGARVTLIERGTIGGTCVNIGCVPSKIMIRSAHIAHLRRESPFDDGLSAQAPVV
DRSALLAQQQARVEELRESKYQSILNDNAAITVLKGEARFVDERTLTVTLNDGGEQTVHFDRAFIGTGARPAEPPVPGLS
ETPYLTSTSALELDHIPERLVVIGASVVAIELAQAFARLGSRVTILARSRVLSQEDPAVGEAVEAAFRREGIEVLKQTQA
SEITHNGRVFTLQTNAGTLEAEQLLVASGRTPNTENLNLEAVGVATERGAIRIDNHLQTTASGIYAAGDCTDQPQFVYVA
AAGGSRAAINMTGGDASLDLSAMPEVIFTDPQVATVGLSEAEAQAQGYDTDSRTLTLDNVPRALVNFDTGGFIKMVAERG
SGRLLGVQSVAGEAGELIQTAVMALRARMTVNDIADELFPYLTMVEGLKLCAQTFTKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 6e-156 72
merA AGK07021.1 MerA Not tested SGI1 Protein 6e-156 72
merA AGK07079.1 MerA Not tested SGI1 Protein 6e-156 72
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-154 72
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 8e-153 72
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 6e-155 72
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 4e-152 71
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-152 71
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-152 71
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-153 71
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-94 44
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-94 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Maqu_0242 YP_957535.1 mercuric reductase BAC0652 Protein 8e-155 71
Maqu_0242 YP_957535.1 mercuric reductase BAC0653 Protein 2e-152 71
Maqu_0242 YP_957535.1 mercuric reductase BAC0650 Protein 2e-147 68
Maqu_0242 YP_957535.1 mercuric reductase BAC0224 Protein 6e-93 45
Maqu_0242 YP_957535.1 mercuric reductase BAC0651 Protein 2e-94 44