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Name : leuS (Mvan_6054) Accession : YP_956812.1 Strain : Mycobacterium vanbaalenii PYR-1 Genome accession: NC_008726 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 6464902 - 6467808 bp Length : 2907 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGACTGAAACGCCGACTGGAACGCAGTCCTCGCGCGAGACTGCCGCCGACGACACGCCCCGCCACCGCTACACCGCGGG CCTCGCCGGGGAGATCGAGCGGGCGTGGCAGCAGCGGTGGACCCAGGACGGGACGTTCGACGTCGCCAACCCGGTCGGAT CACTGGCTCCGGCCGACGGGTCCGCGGTGCCTGCGGACAAGATGTTCGTCCAGGACATGTTCCCGTACCCGTCCGGTGAG GGCCTGCACGTCGGGCATCCGCTCGGCTACATCGCCACCGACGTGTACGCCCGGTACTATCGGATGACCGGTCGAAACGT CCTGCACGCGTTGGGCTTTGATGCGTTCGGGTTGCCGGCCGAGCAGTACGCGATCCAGACCGGCACGCATCCGAGGACGC GTACCGAGGCGAACATCGTGAACTTCCGCCGCCAGCTGGGCCGGCTGGGCCTCGGCCACGATTCGCGGCGCAGCTTCTCC ACCACCGATGTGGACTTCTACAAGTGGACCCAGTGGATCTTCCTGCAGATCTACAACGCGTGGTTCGACACGGCGCAGAA CAAGGCGCGACCCGTCGCGGAGCTGATCGCCGAGTTCGAGGCCGGCACCCGGGAGGTCGGCGACGGCCGTCGGTGGGCGG ATCTGGACGCCGGGGAGCGCGCCGATGTCGTCGACTCGCGCCGGTTGGTGTATCTGGCGGATTCGGTGGTGAACTGGTGT CCGGGCCTGGGCACGGTGCTGGCCAACGAGGAAGTGACCTCCGACGGTCGAAGCGAACGCGGCAATTTCCCGGTGTTCCG GAAAAGGTTGCGGCAGTGGATGATGCGCATCACCGCCTACTCCGACCGGCTGTTGGAGGATCTCGACGTGCTGGACTGGC CGGACAAGGTCAAGACCATGCAGCGCAACTGGATCGGCCGGTCGACCGGAGCCAGCGTGGAGTTCGGCACTGACGCCGGT GACATCGAGGTGTTCACCACCCGCCCGGACACGCTGTTCGGGGCGACGTACATGGTGCTCGCCCCCGAACACGACCTGGT GGACCGGTTGGTCGCCGACCAGTGGCCGGCCGACGTGGACGCCCGGTGGACGTTCGGGGCGGCCACCCCGCGCGAGGCCG TCGCCGCCTACCGGGCCTCGATCGCCGCGAAGTCGGATCTGGAGCGGCAGGAGAACAAGGCCAAGACGGGTGTGTTCATC GGCGCCTATGCGACGAATCCCGCTAACGCGAAACAGGTTCCGGTGTTCATCGCCGACTACGTGCTGGCCGGCTACGGCAC CGGCGCCATCATGGCGGTGCCCGGCGGTGACCAGCGCGACTGGGACTTCGCCACCGAATTCGGGCTGCCCATCATCGAAG TGGTCAGGCCGGTGGCGGACCGACCCGGGGAAGACACCGGGGCCGGAGGCGATGTCTCGCAGGCTGCCTACACCGGCGAC GGTGTGATGGTGAACTCGGGCTTCCTGGACGGGATGGACGTTTCGGCCGCGAAGGAGGCGATGACCGAGCGGCTGAGCGC TGACGGGCGCGGCCGCGAGCGCGTCGAATACAAGCTGCGGGACTGGCTTTTCGCCAGGCAGCGGTACTGGGGTGAGCCGT TCCCGATCGTCTACGACGCCGACGACCGGGCGCACGGCCTGCCCGAGGAGCTGCTGCCCGTCGAGCTGCCCGATGTGCCG GACTACTCGCCGGTGCTGTTCGACCCGGACGATGCCGACAGCGAGCCGTCACCGCCGCTGGCGAAGGCCACCGAGTGGGT GAACGTCGAACTCGACCTCGGCGACGGCCGCAAGCGCTACACCCGCGACACCAACGTGATGCCGCAGTGGGCGGGCAGCT CCTGGTATGAGCTGCGCTACGCCGACCCACACAACACAGAAGCCTTGTGCGCCAAGGAGAACGAGGCCTACTGGATGGGT CCGCGGCCGGCCGAGCACGGCCCCGACGATCCCGGCGGGGTGGACCTGTACGTCGGCGGCGTCGAGCATGCGGTGCTGCA CCTGCTGTACTCGAGGTTCTGGCACAAGGTGCTCTACGACCTCGGCCATGTCAGCTCCCGTGAGCCGTACCGGCGGTTGG TCAACCAGGGCTACATCCAGGCGTTCGCCTACACCGACGCCCGCGGCTCCTACGTCCCTGCCGCCGAGGTGGTCGAACGG GACGGCAAGTTCTTCTGGCCGGGGCCCGACGGGGAAATCGAGGTCAACCAGGAGTTCGGCAAGATCGGCAAGAGCCTGAA GAACTCGGTGTCGCCCGACGAGATCTGCGACGACTACGGCGCCGACACGCTGCGCGTCTACGAGATGTCGATGGGTCCGC TGGAGGCGTCGCGGCCGTGGGCGACCAAGGACGTCGTCGGCGCGCACCGGTTCCTGCAGCGGGTGTGGCGACTGGTGGTC TCGGAAGAGACGGGAGAAACCGTCGTCACCGACGACGCGCTCGATGAGGACACGCTGCGGCTGCTGCACCGCACCATCGC CGGGACGGCCGACGATTACGCAGCGCTGCGCAACAACACCGCGGCCGCCAAGCTGATCGAGTACACCAACCATCTGACCA AGCAGTCGGTGACGGCCAGGGCGGCCCTGGAACCGCTTGTGCTGATGGTCGCACCGCTGGCGCCGCACCTGGCCGAGGAG CTGTGGCGGCGGCTGGGCCACGATGCCTCGCTGGCGCACGGCCCGTTCCCGGTGGCCGACGAGCGCTACCTCGTCGAGGA CACCGTGGAGTACCCGGTGCAGGTCAACGGCAAGGTCCGCGGCCGCGTCACCGTCGCGGCCGACGCGCCGGCCGATGCGG TCGAGGCGGCTGCCCTGGCCGACGACAAGGTCGTCGCGTTCCTGGACGGAAAGACCCCGAAGAAGGTGATCGTGGTCGCG GGCCGCCTCGTCAACGTCGTGCTCTAA Protein sequence : MTETPTGTQSSRETAADDTPRHRYTAGLAGEIERAWQQRWTQDGTFDVANPVGSLAPADGSAVPADKMFVQDMFPYPSGE GLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFS TTDVDFYKWTQWIFLQIYNAWFDTAQNKARPVAELIAEFEAGTREVGDGRRWADLDAGERADVVDSRRLVYLADSVVNWC PGLGTVLANEEVTSDGRSERGNFPVFRKRLRQWMMRITAYSDRLLEDLDVLDWPDKVKTMQRNWIGRSTGASVEFGTDAG DIEVFTTRPDTLFGATYMVLAPEHDLVDRLVADQWPADVDARWTFGAATPREAVAAYRASIAAKSDLERQENKAKTGVFI GAYATNPANAKQVPVFIADYVLAGYGTGAIMAVPGGDQRDWDFATEFGLPIIEVVRPVADRPGEDTGAGGDVSQAAYTGD GVMVNSGFLDGMDVSAAKEAMTERLSADGRGRERVEYKLRDWLFARQRYWGEPFPIVYDADDRAHGLPEELLPVELPDVP DYSPVLFDPDDADSEPSPPLAKATEWVNVELDLGDGRKRYTRDTNVMPQWAGSSWYELRYADPHNTEALCAKENEAYWMG PRPAEHGPDDPGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDARGSYVPAAEVVER DGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICDDYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVV SEETGETVVTDDALDEDTLRLLHRTIAGTADDYAALRNNTAAAKLIEYTNHLTKQSVTARAALEPLVLMVAPLAPHLAEE LWRRLGHDASLAHGPFPVADERYLVEDTVEYPVQVNGKVRGRVTVAADAPADAVEAAALADDKVVAFLDGKTPKKVIVVA GRLVNVVL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-140 | 48 |
