Gene Information

Name : Mvan_5659 (Mvan_5659)
Accession : YP_956430.1
Strain : Mycobacterium vanbaalenii PYR-1
Genome accession: NC_008726
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 6050885 - 6052144 bp
Length : 1260 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGATTGACCTCAAGGTGCTGCGAGAGAATCCGGACGCCGTGCGTGCATCACAGCTGGCGCGGGGCGAGGATCCCGGCCT
TGTCGATGCGCTCGCCGACGCCGACACCGCCAGGCGCGCCGCCATCTCGGCCGCCGACAACCTGCGCGCCGAGCAGAAGT
CGGCCAGCCGGCTGGTCGGGAAGGCCTCACCCGAGGAGCGGCCCGCCCTGCTGGCCGCCGCCAAGGAGCTGGCCGACAAG
GTCAGGGCCGCGGAGTCCGCCCAGGCCGAGGCCGAGAAGGCCTACAGCGCCGCCCACATGGCGATCTCGAACGTCATCAT
CGACGGTGTCCCGGCCGGGGGCGAGGACGACTTCGTGGTGCTCGACACCGTCGGTGAACCGACCGCCCTCACCGATCCGA
AGGACCACCTCGAGCTCGGGGAGTCGCTCGGACTGATCGACATGGAGCGCGGCGCGAAGGTCTCGGGGTCACGTTTCTAC
TTCCTCACCGGATTCGGGGCGCTGCTGCAGCTGGGCCTGTTCCAGCTCGCGGTGCGGACCGCCACCGAGAACGGATTCAC
GCTCGTCATCCCGCCGGTGTTGGTGCGGCCCGAGATCATGTCGGGCACCGGCTTCCTCGGCGCCCACGCCGACGAGGTGT
ACCGGGTGGAGGCCGACGACCTCTACCTGGTCGGAACCTCCGAGGTGCCGCTGGCGGGTTACCACTCCGGCGAGATCCTC
GACCTGTCGGAGGGCCCGAAGCGGTACGCCGGCTGGTCGTCGTGTTTCCGCCGGGAAGCAGGCAGCTACGGCAAGGACAC
CCGGGGCATCATCCGGGTGCACCAGTTCGACAAGGTCGAAGGGTTCGTCTACTGCCGGCCGGAGGAGGCGGAGGCCGAGC
ACGACCGTCTTCTCGGCTGGCAGCGACAGATGCTCGGCCTCATCGAGGTGCCATACCGGGTGATAGACATCGCCGCAGGC
GATCTGGGCTCTTCGGCGGCGCGCAAGTTCGACTGCGAGGCGTGGGTGCCGACCCAGCAGACCTACCGCGAGCTGACCTC
GACGTCGAACTGCACGACGTTCCAGGCCCGCCGGTTGGGGGTGCGCTACCGCGACGAGAACGGCAAACCGCAGACGGCGG
CCACGCTCAACGGCACGCTGGCCACTACCCGCTGGCTGGTGGCCATCCTGGAGAACCATCAGCAGCCCGATGGCAGCGTA
CGGATCCCCGAGGCGCTGGTGCCGTACGTCGGCACCGAGGTGCTCACCCCCAAAAACTAG

Protein sequence :
MIDLKVLRENPDAVRASQLARGEDPGLVDALADADTARRAAISAADNLRAEQKSASRLVGKASPEERPALLAAAKELADK
VRAAESAQAEAEKAYSAAHMAISNVIIDGVPAGGEDDFVVLDTVGEPTALTDPKDHLELGESLGLIDMERGAKVSGSRFY
FLTGFGALLQLGLFQLAVRTATENGFTLVIPPVLVRPEIMSGTGFLGAHADEVYRVEADDLYLVGTSEVPLAGYHSGEIL
DLSEGPKRYAGWSSCFRREAGSYGKDTRGIIRVHQFDKVEGFVYCRPEEAEAEHDRLLGWQRQMLGLIEVPYRVIDIAAG
DLGSSAARKFDCEAWVPTQQTYRELTSTSNCTTFQARRLGVRYRDENGKPQTAATLNGTLATTRWLVAILENHQQPDGSV
RIPEALVPYVGTEVLTPKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-46 43