Gene Information

Name : lysS (Mvan_5360)
Accession : YP_956137.1
Strain : Mycobacterium vanbaalenii PYR-1
Genome accession: NC_008726
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 5736285 - 5737814 bp
Length : 1530 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGGTTCATTTAAGCTGGCACGTCGTGACGTCCCCCGATTCTCCTGACGACATCCCCGAGCAGTTCCGCATCCGTCAGGG
CAAGCGTGACCGGTTGTTGGCCGAAGGGCGTGACCCGTATCCCGTCAAGGTCGACCGCACCCACACCCTCGCGGAGTTGC
GTGCCGCGTATCCGGACCTGCCCGCCGACACCAAGACCGGTCAGGAGGTCGGGGTGGCGGGGCGCGTGATCTTCGCCCGC
AACTCCGGCAAGCTGTGCTTCGCCACGCTGCAGGAGGGGGACGGGACTCACCTGCAGGCGATGATCAGCCTCGACCAGGT
GGGTCAGGACTCGCTCGACGCGTGGAAAGCCGACGTCGACCTGGGCGACATCGTGTTCGTGCACGGTGAGGTGATCAGTT
CCCGGCGCGGCGAACTCTCTGTGCTCGCAGACTCCTGGCAAATCGCATCCAAGGCGCTGCGGCCGTTGCCGGTCGCGCAC
AAGGAGATGAGTGAGGAGTCCCGCGTCCGCCAGCGCTACGTCGACCTGATCGTGCGTCCGGAGGCCCGTGCGATCGCCCG
CCAAAGGGTGGCGGTGGTGCGCGCGGTCCGGAACGCGCTGGAGCGTCGCGGATTCCTCGAAGTCGAGACCCCGATGCTGC
AGACCCTTGCGGGCGGGGCCGCGGCGCGGCCTTTTGTGACGCACTCCAACGCGCTCGACGCCGACCTTTACCTGCGCATC
GCTCCGGAACTTTTTCTGAAGCGCTGTGTGGTGGGCGGATTCGACCGGGTCTTCGAGTTGAATCGGAACTTCAGAAACGA
GGGCGCGGATTCCACGCATTCACCGGAATTCGCGATGCTCGAGACTTATCAGGCCTACGGAACCTACGACGATTCCGCGC
TGGTGACACGTCAACTAATTCAGGAGGTCGCCGACGAAGCCATCGGGACCCGCCAAGTGCCATTGGCCGATGGCTCTGTC
TACGACCTCGACGGCGAATGGGACGACATTCAAATGTATCCCTCATTGTCTGAAGCACTCGGCGAAGAGATCACCCCGCA
GACCGCTGTACCGCGTCTTTGGCGGATCGCCGACGGTTTGGGCGTCGAGATTCCCCGCGACCGCGGATATGGGCACGGGA
AATTGGTCGAGGAACTGTGGGAATTCACGGTCGGTGACAAGTTGTGGGCGCCCACCTTCGTGCGCGACTTCCCGGTCGAG
ACCACACCGCTTACCCGACCGCACCGCAGTATCGAGGGAGTGACGGAGAAATGGGACCTCTACATCCGTAACTTCGAGCT
GGCGACCGGATACTCCGAGTTGGTCGATCCGATCATTCAGCGGGAACGCTTCGAGGAGCAGGCCCGTGCGGCCGCGGCGG
GCGACGACGAGGCAATGGCGCTCGACGAGGATTTCCTGGCGGCCCTGGAGTACGGGATGCCGCCCACCACAGGAACCGGA
ATGGGCATCGATCGCCTGTTGATGGCGTTGACAGGACTGTCGATTAGGGAGACGGTTTTGTTCCCGATTGTTCGCCGACA
CGGCAACTGA

Protein sequence :
MVHLSWHVVTSPDSPDDIPEQFRIRQGKRDRLLAEGRDPYPVKVDRTHTLAELRAAYPDLPADTKTGQEVGVAGRVIFAR
NSGKLCFATLQEGDGTHLQAMISLDQVGQDSLDAWKADVDLGDIVFVHGEVISSRRGELSVLADSWQIASKALRPLPVAH
KEMSEESRVRQRYVDLIVRPEARAIARQRVAVVRAVRNALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDADLYLRI
APELFLKRCVVGGFDRVFELNRNFRNEGADSTHSPEFAMLETYQAYGTYDDSALVTRQLIQEVADEAIGTRQVPLADGSV
YDLDGEWDDIQMYPSLSEALGEEITPQTAVPRLWRIADGLGVEIPRDRGYGHGKLVEELWEFTVGDKLWAPTFVRDFPVE
TTPLTRPHRSIEGVTEKWDLYIRNFELATGYSELVDPIIQRERFEEQARAAAAGDDEAMALDEDFLAALEYGMPPTTGTG
MGIDRLLMALTGLSIRETVLFPIVRRHGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 3e-140 64