Gene Information

Name : Mvan_5358 (Mvan_5358)
Accession : YP_956135.1
Strain : Mycobacterium vanbaalenii PYR-1
Genome accession: NC_008726
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5732997 - 5735540 bp
Length : 2544 bp
Strand : -
Note : PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mmc:Mmcs_4756 ATPase AAA-2

DNA sequence :
ATGTTCGAAAGATTCACCGACCGTGCGCGTCGGGTTGTCGTCCTGGCTCAAGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGACTTATTCACGAGGGTGAGGGCGTTGCCGCCAAGTCACTCGAATCGCTGGGCA
TCTCCCTGGAGGGTGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGACAGCAGGCGCCGTCCGGGCACATCCCCTTT
ACCCCGCGGGCCAAGAAGGTGCTTGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATTCTGCTCGGCCTCATCCGTGAGGGCGAGGGGGTGGCCGCCCAGGTGCTCGTCAAGCTGGGTGCGGAACTCACCCGGG
TGCGCCAGCAGGTGATCCAGCTGCTGAGCGGCTACCAGGGCAAGGAGACCGCCGAGGCCGGTACCGGTGGCCGCGGCGGC
GAGGCGGGCAATCCGTCCACGTCGCTGGTTCTCGACCAGTTCGGCCGCAACCTGACCGCCGCCGCGATGGAGGGCAAGCT
CGACCCCGTCATCGGTCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTGC
TGATCGGTGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGGCTGGCGCAGGCGATCGTGCACGGCGAGGTCCCGGAG
ACGCTGAAGGACAAGCAGCTCTACACGCTGGATCTGGGCTCGCTGGTCGCGGGCAGCCGCTACCGCGGTGACTTCGAGGA
GCGCCTGAAGAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTCGTCG
GCGCGGGTGCCGCCGAGGGGGCGATCGACGCCGCCAGCATCCTCAAGCCGAAGCTGGCCCGCGGCGAGCTGCAGACCATC
GGCGCCACCACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAGCGCCGGTTCCAGCCGGTGCAGGT
GGGCGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGTCTGCGGGACCGCTACGAGGCGCACCACCGCGTCTCGA
TCACCGACTCGGCGCTGGTCGCGGCGGCCACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCCGGTGCCCGCATGCGGATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAA
GATCGCCGACGCGCGCCGGGAGAAGGAATCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGAGCCTGCGCGACAAGG
AGAAGCAGCTGGTCGCGCAGCGCGCCGAGCGTGAGAAGCAGTGGCGCTCAGGCGATCTCGATGTGGTCGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTTCTCGGCAACTGGACCGGTATCCCGGTGTTCAAGCTGACCGAGGAGGAGACCACGCGTCT
GCTCCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGATGCCGTCAAGGCCGTCTCCAAGGCGATCCGCC
GCACCCGCGCCGGGTTGAAGGACCCCAAGCGCCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAGCTGTCCAAGGCGCTGGCCAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCATCGCGGCTGTTCGGCGCCCCTCCCGGGTACGTCGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGCAAGCCGTTCTCCGTGGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACAGCCTCCTGCAG
GTGCTCGAAGACGGCCGCCTGACCGACGGTCAGGGCCGCACGGTCGACTTCAAGAACACCGTGCTGATCTTCACCTCGAA
CCTCGGTACGAGCGACATCAGCAAGGCGGTCGGGCTCGGCTTCACCCAGGGTGGCGGCGAGAACAACTACGAGCGGATGA
AGCAGAAGGTTCACGACGAACTCAAGAAGCACTTCCGTCCGGAGTTCCTCAACCGCATCGACGACATCATCGTGTTCCAC
CAGCTGACTCAGGACGAGATCATCAAGATGGTCGACCTGATGATCGGCCGGGTTTCCAAGCAGTTGGCGGCCAAGGACAT
GACGATGGAGCTGACCGACAAGGCCAAGTCCCTGCTGGCCAAGCGCGGCTTCGATCCGGTGCTGGGCGCCCGGCCGCTGC
GCCGGACCATCCAGCGCGAGATCGAGGACCAGCTGTCGGAGAAGATCCTCTTCGAGGAGGTCGGCCCCGGCCAGCTCGTC
ACCGTCGACGTCGAGGGCTGGGACGGCGAGGGCGCGGGCGAGGATGCGAAGTTCACGTTCATCGGCACCAAGAAGCCGGT
GAAGATCGAGGAGCCGGATCTTGCGCAGGCCGGCGCGGCAGGCGGGCCCAGCGCGGCCGAGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAEAGTGGRGG
EAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIKMVDLMIGRVSKQLAAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQLV
TVDVEGWDGEGAGEDAKFTFIGTKKPVKIEEPDLAQAGAAGGPSAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 83

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mvan_5358 YP_956135.1 ATPase VFG0079 Protein 0.0 61
Mvan_5358 YP_956135.1 ATPase VFG0080 Protein 2e-146 51