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Name : Mvan_0034 (Mvan_0034) Accession : YP_950891.1 Strain : Mycobacterium vanbaalenii PYR-1 Genome accession: NC_008726 Putative virulence/resistance : Unknown Product : N-6 DNA methylase Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : - Position : 41676 - 43310 bp Length : 1635 bp Strand : + Note : PFAM: N-6 DNA methylase; KEGG: mbo:Mb2777c possible type I restriction/modification system DNA methylase HsdM (M protein) (DNA methyltransferase) DNA sequence : ATGCCGCCGAGAAGGGGCACGAAAAAGGCTGAGCCACTGCTTCCTTCAACGATGAAGGAGCTGAAGGACACACTGTGGAA AGCCGCCGACAAACTGCGCGGATCGCTGTCAGCCAGCCAGTACAAGGATGTGATCCTGGGCCTGGTGTTCCTCAAGTACG TCTCCGACGCCTACGACGAACGCCGCGAGGCGATCCGGACGGAGCTGGAGGCAGACGGCCTCGACGCCGAACAGATCGAA GACCTCATCGAGGATCCCGAGGAGTACCAGGGCTACGGCGTGTTTGTCGTCCCGCCCGGCGCGCGGTGGAAGTTCCTGGC GGAGAATGCGAAGGGTTTACCGGCCGCCGGTGGCGAGCCCGCCAAGAACATCGGTCAGCTGATCGACGAGGCGATGGACG CCGTGATGAAGGCCAACCCGACCCTGCAGGGCACCCTGCCGCGGCTGTACAACAAGGACAACATCGACCAGCGCCGGTTG GGTGAATTGATCGACCTGTTCAACAGCGCCCGGTTCAGCCGCCAGGGTGACGGCCGAGCGCGCGACCTGATGGGCGAGGT CTACGAGTACTTCCTCGGCAACTTCGCGCGGGCGGAAGGGAAGCGGGGTGGAGAGTTCTTCACCCCGCCGAGCGTGGTGA AGGTGATCGTCGAGGTGCTGGAACCGTCGCGCGGGCGGGTGTATGACCCGTGCTGCGGATCGGGCGGCATGTTCGTGCAG ACCGAGAAGTTCATCTATGAGCACGACGGCGACCCGAAGGAGATCGCCGTCTACGGTCAGGAGTCCATCGAGGAGACCTG GCGGATGGCCAAGATGAACCTGGCCATCCACGGCATCGACAACAAGGGCCTGGGTGCGCGCTGGGGCGATACCTTTGCCC GTGACCAGCATCCCGATGTCCAGATGGATTACGTGCTGGCCAATCCGCCGTTCAACATCAAGGACTGGGCCCGCAACGAG GAGGACGCCCGCTGGCGGTTCGGCGTACCGCCGGCCAACAACGCCAACTACGCCTGGATCCAGCACATCCTGTACAAGCT GGCGTCCGGCGGTAAGGCCGGTGTGGTGATGGCCAATGGGTCGATGTCGTCGAACTCCAACGGCGAGGGCGATATCCGGG CCCAGATCGTCGAAGCCGATCTGGTGTCATGCATGATCGCGCTGCCCACCCAGTTGTTTCGCAGCACCGGAATCCCGGTG TGCGTGTGGTTCTTCGCCAAGGACAAAACCGCAGGTAAGCAGGGCTCGGTCGACCGGTCGGGGCAGGTGCTGTTCATTGA CGCCCGCGAGATGGGCTACATGGTCGACCGCGCTGAGCGCGCCCTCTCCGACGACGACATCGTCAAGATCGGCGACACCT TCCATGCCTGGCGCGGATCGGCGTCGGCGGCAGCGAAGGGCGTTGTCTACCAGGATGTCCCAGGCTTTTGTAAGTCGGCG ACCCTAGCCGAAATCAAGGCTGCCGACTACGCACTGACACCGGGACGGTACGTCGGCGCTGCGGCCGTCGAGGACGACGG CGAACCGATCGACGAGAAAATCGCCCGGTTGAAGACGGAACTGCTTGCGGCGTTTGATGAGTCGGCGCGGCTGGAGAAGG TGGTTCGAGAGCAGTTGGAGCGGATCGATGCGTGA Protein sequence : MPPRRGTKKAEPLLPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRTELEADGLDAEQIE DLIEDPEEYQGYGVFVVPPGARWKFLAENAKGLPAAGGEPAKNIGQLIDEAMDAVMKANPTLQGTLPRLYNKDNIDQRRL GELIDLFNSARFSRQGDGRARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSRGRVYDPCCGSGGMFVQ TEKFIYEHDGDPKEIAVYGQESIEETWRMAKMNLAIHGIDNKGLGARWGDTFARDQHPDVQMDYVLANPPFNIKDWARNE EDARWRFGVPPANNANYAWIQHILYKLASGGKAGVVMANGSMSSNSNGEGDIRAQIVEADLVSCMIALPTQLFRSTGIPV CVWFFAKDKTAGKQGSVDRSGQVLFIDAREMGYMVDRAERALSDDDIVKIGDTFHAWRGSASAAAKGVVYQDVPGFCKSA TLAEIKAADYALTPGRYVGAAAVEDDGEPIDEKIARLKTELLAAFDESARLEKVVREQLERIDA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 1e-126 | 50 |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 5e-126 | 50 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 8e-126 | 49 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 1e-112 | 46 |
