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Name : lysS (Mvan_3330) Accession : YP_954133.1 Strain : Mycobacterium vanbaalenii PYR-1 Genome accession: NC_008726 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 3541858 - 3545160 bp Length : 3303 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGACGCCAACCAGCCTCGCCCGGGCCCGTCCGACGTCCAGCCACCGCTGGGTGCCCGCGGCCGCCGGGTGGATCGTGGG GGTCATCGCGACGCTGTCGCTGCTGGCCAGCGTCTCGCCGCTGGTCCGGTCCCTGATCCGGGTCCCGCGCGAGTGGGTCG ACGACTACATCTTCAACTTCCCCGACACCAGTTTCGCGTGGGCGTTCGTGCTGGCGCTGCTCGCCGCCGCCCTGGCCGCG CGCAAACGCATCGCCTGGTGGATCCTCGTCGGCTACATGATCGCGGCGGCCGGTTGGAACATCGCCGGTCTGGCCGAGGG CCGAGAACGCTGGTTCGCCGAGGTCGGCGAGGTCATCGGTCTGGCGTTTCACCTGGCCGCCATCGCGTTCCTGCTGCTTG CCCGCAAGGAGTTCTGGGCCAGGGTGCGCCGCGGCGCGTTGCTCAAGGCCGCCGCGACGCTGGTGGCGAGCATGGCCGTC GGCACACTCATCGGCTGGGGTCTGCTCGAACTGTTCCCCGGATCCCTGGCCCGGTCGGACCGGTTCCTGTACGCGCTGAA CCGGGTCAGCGCGTTCGCCGGGGCCGACGCCGCGTCGTTCAGCGGTCATCCGCACGTGTTCGTCAACGCGCTGCTCGGCC TGTTCGGGGCGGTGGCCCTGATGGTCACGGCGATCGTGCTGTTCCAGTCGCAGCGCGCGGACAACGCGCTCACCGGTGAG GACGAGTCGGCGATCCGCGGTCTGCTCGAGCTGTACGGCAAGAACGACTCGCTGGGCTATTTCGCGACCCGGCGCGACAA GGCCGTGGTGTTCGCGCCCAGCGGCCGCGCCGCGATCACCTACCGCGTGGAGGTCGGGGTGTGTCTGGCCAGCGGCGACC CGGTCGGTGACCCCAGGTCCTGGCCGCAGGCGATCGACGCGTGGCTCAAGCTGTGCCAGGCCTACGGCTGGGCGCCGGGC GTGATGGGCGCGAGCGCAGCTGGCGCACAAGCCTTTCGAGAGGCCGGGCTCAACGCCCTGCAACTCGGCGACGAGGCGAT CCTGCATCCGGAGGACTTCCGGTTGTCCGGGCCCGACATGCGGGCCGTCCGGCAGGCGGTGACCCGCGCCCGGCGTGCCG GCGCCACCGTGCGGATCCGCAGGCACCGGGAGCTGCCCGCCGACGAGATGGCCGCGGTCATCGAGCGGGCCGATGCCTGG CGCGACACCGACGACGAGCGCGGGTTCTCGATGGCGCTGGGGCGGCTCGGCGATCCCGCCGACGGGGACTGCCTGCTGGT GGAGGCGGTGCAGGCCGACCAGGTGGTCGCGATGCTGTCGCTGGTGCCATGGGGCGGCAACGGAGTGTCCCTCGATCTGA TGCGCCGTTCCCCGCAATCCCCCAACGGCACCATCGAATTGATGGTCAGCGAGCTGTGCATGCAGTCCGAGGACATCGGC ATCACCCGGATCTCGTTGAATTTCGCGATGTTCCGCTCGGCCTTCGAGCAGGGCGCCCAACTGGGCGCGGGTCCGGTGGC AAGGCTGTGGCGGTGGCTGCTGGTGTTCTTCTCGCGCTGGTGGCAGCTGGAGACCCTGTACCGGTCGAACATGAAGTACC AGCCCGAATGGGTTCCCCGGTACGCGTGCTACGACGACGCCAGGCTGGTGCCCCGCGTCGGCGTGGCCTCTGTGATCGCC GAAGGCTTTCTCGTGCTGCCGTTCTCGCGGCGCCATGAACAGCCGCACACCGGCCACCACATCGCCGCCCCCGGAACACT GGTGGCCACCGGCCTGTTGCACAGCGACGGCACCGCACCCGACGGGATGGGACTGCAGGCCGACCTGGCCGACGACGACC AGCCGAGGCTGCCCGAGCAGGTCCGGGTCAGGATGGCCAAACTCAAGGCGCTTCAAGCCCAGGGGGTCGACGCGTATCCG GTGGCCAACCCGCCCAGCCACACCGTCGCGCAGGCTCTGGCCGCCGAGGACGGCGCAGACGTCGCGGTCGCGGGCCGGGT GCTGCGGTCACGCGACTACGGCGGCGTGCTGTTCGCCCAGCTCCGCGACTGGTCAGGCGAAACCCAACTGGTGCTGGACA ATTCGCTGCTCGCCGACGGCAGCACCGCGGACTTCACCCGGACCATCGACCTCGGTGACCTGATCGAGGTCACGGGCACG ATGGGCCGCAGCCGGTCGGGCAAGTGGTCACTGCTGGTCAGCGGCTGGCGGCTGATCGGAAAGTGCCTGCGCCCGTTACC GGACAAGTGGAAGGGCCTGACCGATCAGGAGGCGCGGGTCCGCGCCCGCTATGTCGATCTCGCGGTCAACACCGATGCCC GGGAGCTGATCCGGGCCCGCAGCGCGGTGCTGCACGCGATCCGCGAGACCCTGGTCGCCAAAGACTTCCTGGAAGTCGAG ACGCCGATCCTGCAACAGATTCACGGCGGTGCGAATGCCCGGCCCTTCCTGACCCACATCAACGCCTACGACCTCGACCT GTATCTGCGGATCGCGCCCGAGCTGTATCTGAAGCGGTTGTGCGTCGGTGGTGTGGAGCGGGTGTTCGAACTCGGACGCG CCTTCCGCAACGAGGGTGTCGACTTCAGCCACAACCCGGAGTTCACGCTGCTGGAGGCGTATCAGGCGCACGCCGACTAC CACGTGTGGATCGACGGTTGCCGGGAGCTGATCCAGAACGCCGCGCAGGCGGCCAACGGTGCGCAGGTGTTCATGCGGCC CCGTGCGGACGGGGTTCTTGAGCCCGTCGACATCTCCGGTCCGTGGACGGTCAAGACCGTGCACGGCGCGGTGTCCGAGG CGCTCGGCGAGCAGATCGGCCCGGACACCGATCTGGCCACGTTGCGCCTGCTCTGCGACCGCGCGGGCATTCCCTACCTG ACGCACTGGGACGCCGGAGCGGTGGTGCTCGAGCTGTACGAGCACCTCGTCGAGGACCAGACCCGGGAACCGACGTTCTA CAAGGACTTCCCCACCTCGGTCTCTCCGCTGACGCGGCCGCACCGCAGCATCCCCGGGGTGGCCGAGCGCTGGGACCTGG TGGCCTGGGGTGTCGAACTCGGCACCGCCTACAGCGAGCTCACCGATCCGGTCGAGCAGCGCCGCCGTCTGCAGGAGCAG TCGCTGCTCGCCGCGGGCGGTGACCCGGAAGCGATGGAGCTCGACGAGGACTTCCTGCAGGCGATGGAGTACGCGATGCC TCCGACGGGCGGGCTGGGGATGGGCGTGGACCGGGTGGTCATGCTCATCACCGGGCGCAGCATCCGCGAGACCCTGCCCT TTCCGCTGGCAAAACCGCGGTAA Protein sequence : MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASVSPLVRSLIRVPREWVDDYIFNFPDTSFAWAFVLALLAAALAA RKRIAWWILVGYMIAAAGWNIAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEFWARVRRGALLKAAATLVASMAV GTLIGWGLLELFPGSLARSDRFLYALNRVSAFAGADAASFSGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALTGE DESAIRGLLELYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVCLASGDPVGDPRSWPQAIDAWLKLCQAYGWAPG VMGASAAGAQAFREAGLNALQLGDEAILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPADEMAAVIERADAW RDTDDERGFSMALGRLGDPADGDCLLVEAVQADQVVAMLSLVPWGGNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIG ITRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYDDARLVPRVGVASVIA EGFLVLPFSRRHEQPHTGHHIAAPGTLVATGLLHSDGTAPDGMGLQADLADDDQPRLPEQVRVRMAKLKALQAQGVDAYP VANPPSHTVAQALAAEDGADVAVAGRVLRSRDYGGVLFAQLRDWSGETQLVLDNSLLADGSTADFTRTIDLGDLIEVTGT MGRSRSGKWSLLVSGWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIRARSAVLHAIRETLVAKDFLEVE TPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADY HVWIDGCRELIQNAAQAANGAQVFMRPRADGVLEPVDISGPWTVKTVHGAVSEALGEQIGPDTDLATLRLLCDRAGIPYL THWDAGAVVLELYEHLVEDQTREPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQEQ SLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 2e-153 | 42 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 6e-153 | 42 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 2e-153 | 42 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 2e-153 | 42 |
