Gene Information

Name : Mvan_2824 (Mvan_2824)
Accession : YP_953637.1
Strain : Mycobacterium vanbaalenii PYR-1
Genome accession: NC_008726
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2995662 - 2997080 bp
Length : 1419 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
GTGAATAGACGCGGAAAGATCGTCTGTACGCTTGGCCCGGCCACGGCTACCGAGGAAGCAGTCAGGCAGCTGGTCGAGTC
GGGGATGGACGTGGCCCGGCTCAACTTCAGCCACGGTGACTACCCCGACCATGAGGCCAACTACAAGCGGGTTCGTGCTG
CGTCCGACGCCACCGGACGGGCGGTCGGAATCCTCGCTGACCTGCAGGGACCCAAGATCCGGCTGGGCAGGTTCGCCGAC
GGGCCGACGATGTGGGCCAACGGTGAGACGGTCCGGATCACCGTCGAGGACTTCGTCGGCAACCACGACCGGGTGTCGAC
GACCTACAAGCGCCTGGCGCAGGACGCCAAGCCCGGCGACCGCGTCCTCGTCGACGACGGCAACGTCGGTCTGGTTGTCG
AGCACATCGACGGCAACGACGTGGTCTGCACGGTCACCGAGGGCGGCAAGGTCAGCAACAACAAGGGCATGTCCCTTCCC
GGGATGAACGTCTCGGCGCCCGCGCTGTCGGAGAAGGACATCGACGATCTCGAGTTCGCGTTGCGCCTCGGTGTCGATCT
GGTCGCCCTGTCGTTCGTGCGGTCACCCGCCGACGTCGAACTGGTCCACGAAGTGATGGACCGCGTCGGCAGGCGGGTGC
CCGTCATCGCGAAACTGGAGAAGCCGGAGGCGATCGACAACCTCGAAGCCATCGTGCTCGCCTTCGATGCGATCATGGTC
GCCCGCGGAGACCTCGGCGTGGAGCTGCCGCTGGAGGAAGTGCCGCTGGTCCAGAAGCGCGCCATCCAAATGGCAAGAGA
GAACGCCAAACCCGTCATCGTCGCCACGCAGATGCTGGAATCGATGATCGAGAACTCGCGCCCCACCCGCGCCGAGGCGT
CCGACGTCGCCAACGCGGTGCTCGACGGTGCCGACGCGGTGATGCTGTCCGGGGAGACCTCGGTGGGCAAGTTCCCGTTC
GAGACGGTGCGGACGATGGCGCGCATCATCAAGGCGGTGGAGGAAAACTCGGTGGCAGCACCGCCGCTGACCCACGTGCC
CCGCACCAAGCGCGGCGTCATCTCCTACGCCGCCCGCGACATCGGCGAGCGGCTCGACGCCAAGGCGCTGGTGGCGTTCA
CCCAGTCCGGGGACACCGTCCGCCGGCTGGCCCGCTTGCACACGCCGCTGCCGGTGCTGGCGTTCACGGCGCTGCCGGAG
GTGCGCAGCCAGCTGGCGCTGACCTGGGGCACCGAGACGTTCATCGTCCCGCACATCGACACCACCGACGGAATGATCCG
CCAGGTGGACCAGTCGATGCTGAACCTGGGCCGCTACAAACGGGGCGACCTCGTGGTCATCGTCGCCGGGGCGCCCCCCG
GCACAGTAGGCTCCACGAATCTGATCCACGTCCACCGCATCGGGGAGGACGACGTCTAG

Protein sequence :
MNRRGKIVCTLGPATATEEAVRQLVESGMDVARLNFSHGDYPDHEANYKRVRAASDATGRAVGILADLQGPKIRLGRFAD
GPTMWANGETVRITVEDFVGNHDRVSTTYKRLAQDAKPGDRVLVDDGNVGLVVEHIDGNDVVCTVTEGGKVSNNKGMSLP
GMNVSAPALSEKDIDDLEFALRLGVDLVALSFVRSPADVELVHEVMDRVGRRVPVIAKLEKPEAIDNLEAIVLAFDAIMV
ARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKFPF
ETVRTMARIIKAVEENSVAAPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPVLAFTALPE
VRSQLALTWGTETFIVPHIDTTDGMIRQVDQSMLNLGRYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-66 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mvan_2824 YP_953637.1 pyruvate kinase VFG0479 Protein 4e-67 41