Gene Information

Name : Mvan_2720 (Mvan_2720)
Accession : YP_953533.1
Strain : Mycobacterium vanbaalenii PYR-1
Genome accession: NC_008726
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2880769 - 2882862 bp
Length : 2094 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACCACGATCGAAGAGATCACTTCCCTCACCCGGCCCAATCACCCGGAGGACTGGACGGACCTGGATTCGCGGGCGGT
CGACACCGTCCGGGTGCTGGCCGCCGACGCCGTCCAGAAGGTCGGCAACGGCCACCCCGGCACCGCGATGAGCCTGGCCC
CGCTGGCCTACACGCTGTTCCAGCGCCAGATGAGGCACGACCCCAGCGACGTGCACTGGCTCGGCCGCGACCGGTTCGTG
CTGTCCTGCGGACACTCCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTCGAGCTCTCCGACATCGA
GTCGCTGCGGACGTTCAAGTCCAAGACGCCCGGCCACCCCGAGTTCCGCCATACCCCCGGCGTGGAGATCACCACCGGCC
CGCTCGGTCAGGGCCTGGCCTCCGCGGTCGGCATGGCGATGGCGGCCCGCTACGAGCGCGGCCTCTTCGACCCCGACGCC
GCCCCGGGCGCCAGCCCGTTCGACCACTACATCTACGTGATCGCCTCCGACGGCGACATCGAGGAGGGCGTCACCAGTGA
GGCGTCCTCACTGGCCGGCACCCAGCAGCTGGGCAACCTGATCGTGTTCTACGACAAGAACCACATCTCGATCGAGCACG
ACACCGACATCGCGCTGTCCGAGGACGTCGCCGCCCGCTACCGGGCCTACGGCTGGCATGTCCAGGAGGTCGAGGGCGGC
GAGAACATCGTCGGTATAGAGGAGGCGGTACAGGCCGCGAAAGCCGTGACCGACAAGCCGTCGTTCATCTCGGTGCGCAC
GATCATCGGCTATCCGGCCCCGAACAAGATGAACACCGGCGGTGTGCACGGTTCGGCGCTCGGCGCCGACGAGGTGGCCG
CCACGAAGAAGATCCTGGGCTTCGATCCCGACAAGACCTTCGAGGTCAGCGAGGACGTCATCACCCACACCCGCGAGTTG
GTGGGTCGCGGCAAGCAGGCCCACGACGCGTGGCAGCAGGACTTCGACGCGTGGGCGGCGCGGGAGCCGGAGCGCAAGGC
GCTGCTGGACCGGCTGCTGGCCCAGGAACTGCCTGAGGGCTGGGACGCCGACCTCACCTACTGGGAACCCGGCTCCAAGG
CGGTGGCCACCCGCGCGGCATTCGGCCAGGTGCTCAACGACGTCGCGCCGAAGCTGCCCGAGTTATGGGGCGGCTCCGCG
GACCTGGCGGGCAGCAACAACACCACCATCAAGGGCGTGAAATCGTTTGGTCCGCCCTCGATTTCGACTGACGACTTCAC
CGCGGACTGGTACGGGCGGGTGCTGCACTTCGGCATCCGCGAGCACGCCATGGGCTCGATCCTGTCGGGCATCGTGCTGC
ACGGTCCGACCCGCGCGTTCGGCGGGACGTTCCTGCAGTTCTCCGACTACATGCGTCCCGCGGTGCGGCTGGCGTCGCTG
ATGGACATCGACACCATCTACATCTGGACGCACGACTCGATCGGCCTGGGTGAGGACGGTCCCACCCACCAGCCCATCGA
GCACCTGGCTGCGCTGCGCGCGATCCCCAACCTGTCGGTGGTGCGCCCCGGTGACCCGAACGAGACCGCCTACGCGTGGC
GCAGCATCGTCGCCCGTGGAAACGGCAGCGGCCCGGTCGGTTTCATCCTGACCCGGCAGGGCATCCCGGTGCTGGAAGGC
ACCGACTCCGACGGAGTGGCCCGCGGCGGGTACGTGTTGGGTGGTGGGAACCCGGCCGACGACGCCGACGTGCTTCTGAT
CGCGACCGGTTCAGAACTGCAGCTGGCGGTCGAGGCGAAGAAGCTGCTGGCGGAAAAGGACATCACCGCCTACGTGGTGT
CGATGCCCTGCGTCGAGTGGTTCGAGTCGCAGCCGAAGGAATACCGCGACAGCGTTCTTCCCCCGGATGTGTCCGCAAGG
GTGGCCATCGAGGCGGCGGTCGCGCAGAGTTGGTACAAGCTCGTCGGCGACACCGGCGAGATCATCTCCATCGAGCACTA
CGGCGAATCCGCCGACGACAAGACGCTGTTCCGCGAATTCGGTTTCACCCCAGAGGCAGTGGTGGCCGCGGCGGAACGCA
CCATCGCAAATTAG

Protein sequence :
MTTIEEITSLTRPNHPEDWTDLDSRAVDTVRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRQMRHDPSDVHWLGRDRFV
LSCGHSSLTLYIQLYLGGFGLELSDIESLRTFKSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMAARYERGLFDPDA
APGASPFDHYIYVIASDGDIEEGVTSEASSLAGTQQLGNLIVFYDKNHISIEHDTDIALSEDVAARYRAYGWHVQEVEGG
ENIVGIEEAVQAAKAVTDKPSFISVRTIIGYPAPNKMNTGGVHGSALGADEVAATKKILGFDPDKTFEVSEDVITHTREL
VGRGKQAHDAWQQDFDAWAAREPERKALLDRLLAQELPEGWDADLTYWEPGSKAVATRAAFGQVLNDVAPKLPELWGGSA
DLAGSNNTTIKGVKSFGPPSISTDDFTADWYGRVLHFGIREHAMGSILSGIVLHGPTRAFGGTFLQFSDYMRPAVRLASL
MDIDTIYIWTHDSIGLGEDGPTHQPIEHLAALRAIPNLSVVRPGDPNETAYAWRSIVARGNGSGPVGFILTRQGIPVLEG
TDSDGVARGGYVLGGGNPADDADVLLIATGSELQLAVEAKKLLAEKDITAYVVSMPCVEWFESQPKEYRDSVLPPDVSAR
VAIEAAVAQSWYKLVGDTGEIISIEHYGESADDKTLFREFGFTPEAVVAAAERTIAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-112 43
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-113 42