Gene Information

Name : Mvan_1468 (Mvan_1468)
Accession : YP_952306.1
Strain : Mycobacterium vanbaalenii PYR-1
Genome accession: NC_008726
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1559571 - 1561094 bp
Length : 1524 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: mpa:MAP3952 aldehyde dehydrogenase

DNA sequence :
ATGACTGTGTACGCCCGCCCCGGTGCTGACGGCTCTTTGATGTCGTTCAAGCCCCGCTACGACAACTTCATCGGCGGCCA
GTGGGTGGCGCCGAATGCTGGACGGTACTTCGAGAACCCATCGCCGGTCACCGGCCAGCCGTTCACCGAGGTGGCCCGCT
CCGACGAATCCGACATCGAGAAGGCCCTCGACGCCGCCCACGCCGCCGCGCCGGCCTGGGGCAAGACCTCGGCCGCCGAG
CGTGCCGTGATCCTCAACAAGATCGCCGACCGCATCGAGGAGAACCTCGAGTCGATCGCGCTGGCCGAGTCGTGGGACAA
CGGCAAGCCGATCCGCGAGACGCTCAACGCCGACATCCCGCTGGCCGTGGATCACTTCCGGTATTTCGCCGGGGCGATCC
GGGCGCAGGAGGGTTCGCTGTCCGAGATCGACGACGACACCGTGGCCTACCACTTCCATGAGCCGCTCGGTGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGATTCTGATGGCGGTCTGGAAGCTGGCCCCCGCGCTGGCCGCGGGCAACGCGATCGT
GCTGAAGCCCGCCGAGCAGACCCCGGCCTCGATCCTGTACCTGATGGAACTCATCGCGGATCTGCTGCCTGCGGGAGTGA
TCAACGTGGTCAACGGTTTCGGTGTCGAGGCGGGCAAGCCGCTGGCATCCAGCAACCGGATCGCCAAGATCGCGTTCACC
GGAGAAACCACCACGGGCCGGCTGATCATGCAGTACGCGTCGCAGAACCTGATCCCGGTCACCCTTGAGCTCGGCGGCAA
GAGCCCCAACATCTTCTTCAACGACGTGCTCGCCCAGGCCGACAACTACCAGGACAAGGCGCTCGAGGGCTTCACGATGT
TCGCCCTCAACCAGGGCGAGGTGTGTACCTGCCCGTCGCGCTCGTTGATCCAGGCCGACATCTACGACGAGTTCCTGGCG
CTGGCCGCGATCCGCACCAAGGCTGTGCGCCAGGGCGATCCGCTGGACACCGAGACGATGATCGGCGCGCAGGCCTCCAA
CGACCAGCTGGAGAAGATCCTGTCCTACATCGAGATCGGCAAGAGCGAGGGTGCGCAGGTGGTCACCGGCGGTGAACGCG
CCGAGCTCGGCGGCGATCTCAACGGCGGCTACTACGTCGCCCCGACGATCTTCACCGGTCACAACAAGATGCGGATCTTC
CAGGAGGAGATCTTCGGGCCCGTCGTCGCCGTCACGTCGTTCACCGACTACGACGACGCGATCTCCATCGCCAACGACAC
CCTCTACGGTCTCGGTGCCGGTGTGTGGAGCCGCGACGGCAACACCGCCTACCGCGCGGGTCGCGACATCAAGGCCGGCC
GGGTGTGGACGAACTGCTACCACCAGTACCCCGCGCACGCCGCGTTCGGTGGCTACAAGCAGTCCGGCATCGGCCGCGAG
AACCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACAGCGACAAGGCCCTCGGGTTCTT
CTGA

Protein sequence :
MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPVTGQPFTEVARSDESDIEKALDAAHAAAPAWGKTSAAE
RAVILNKIADRIEENLESIALAESWDNGKPIRETLNADIPLAVDHFRYFAGAIRAQEGSLSEIDDDTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPASILYLMELIADLLPAGVINVVNGFGVEAGKPLASSNRIAKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFNDVLAQADNYQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLA
LAAIRTKAVRQGDPLDTETMIGAQASNDQLEKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTIFTGHNKMRIF
QEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAGRDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRE
NHKMMLDHYQQTKNLLVSYSDKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-149 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-158 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-158 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-158 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-157 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mvan_1468 YP_952306.1 aldehyde dehydrogenase VFG0082 Protein 6e-150 63