Gene Information

Name : guaA (AAur_2857)
Accession : YP_948566.1
Strain : Arthrobacter aurescens TC1
Genome accession: NC_008711
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3133485 - 3135074 bp
Length : 1590 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTACTCCCACCGCACCCCAAACTTCCCAGAAGCCGGTGCTGGTTGTTGACTACGGTGCCCAGTACGCGCAGCTGAT
TGCCCGCCGCGTCCGCGAAGCGAATGTGTATTCGGAAATCGTTCCGCATACCTTCACCACCGAGCAGCTTCTGGCCAAGA
ACCCGGCAGCCATCATTCTCTCCGGAGGGCCCTCCAGCGTCTACGCCGAGGGCGCTCCGAGCGTCGGCGCAGATCTTTTC
GAAGCCGGGGTGCCCGTTTTCGGCATCTGCTACGGCTTCCAGGCCATGGCAAATGCCTTGGGTGGCAAGGTGGCCCAGAC
GGGTCTCCGGGAGTACGGCGCAACCGAAGCACTGGTTGTAGGCGACGCCCGCTCCATTCTGGATGGCGTTCCCTCTTCCC
AGAACACCTGGATGAGCCATGGCGACTCCGTTCACGAAGCCCCTGAGGGCTTCGAGGTGCTTGCCTCCACAGCTGGTGCA
CCGGTGGCTGCTTTCGCCAATGACGAGAAGCGCCTCTACGGTGTGCAGTGGCACCCCGAGGTCAAGCACTCCGTACACGG
CCAACACGTCCTGGAGAACTTCCTGTTCAAGGGTGCGGGCCTGAGCCCCAACTGGACCACCGGCAACATCCTCGAAGAGC
AGGTGGACCGTATCCGCCAGCAGATCGGCGACTCCAAGGTCATCTGCGGTCTCTCCGGTGGTGTCGACTCCGCAGTGGCC
GCCGCTCTCGTCCAGCGCGCCGTCGGCGACCAGTTGACCTGTGTCTTCGTGGACCACGGCCTCCTGCGTGAAGGCGAAGC
CGAGCAGGTTGAGCGCGACTTTGTGGCAGCCACGGGTGTCAACCTGTACGTTGCCAACGAGCAGGAACGTTTCCAGTCCG
CATTGGCCGGTGTCAGCGATCCCGAGACCAAGCGCAAGATCATTGGCCGGGAATTCATTCGCGCCTTCGAAGAAGCGGAA
CGGGCCATCATCGCCCAGGCCGCTGCCGAGGGTGAAAAGATCAAGTTCCTTGTCCAAGGCACGCTGTACCCGGACGTCGT
CGAGTCCGGCGGCGGCGAGGGCGCTGCAAACATCAAGAGCCACCACAATGTGGGCGGGCTCCCGGAAGACCTGCAGTTCG
AGCTCGTTGAGCCGCTGAGGGCACTGTTCAAGGACGAAGTTCGTGCTGTTGGTGCCCAACTCGGCCTCCCGCAGGAAATC
GTTGGCCGCCAGCCATTCCCCGGCCCCGGCTTGGGAATCCGCATTGTGGGTGAAGTGACCAAGGAGCGCCTGGACCTGCT
GCGCAAGGCCGATGCCATCGCCCGCGCCGAGCTGACAGCTGCCGGTCTGGACAATGACGTATGGCAGATGCCGGTAGTCC
TTCTGGCTGATGTCCGCAGCGTAGGTGTTCAGGGCGACGGTCGGACCTATGGTCACCCGATCGTGCTGCGTCCGGTCTCC
TCCGAGGACGCCATGACAGCAGACTGGTCGCGGTTGCCGTATGACCTGCTTGCCCGGATCTCCAACAGGATCACCAATGA
GGTGGACGGAGTTAACCGCGTGGTACTGGACGTCACCAGCAAGCCCCCGGGAACCATCGAGTGGGAATAG

Protein sequence :
MTTPTAPQTSQKPVLVVDYGAQYAQLIARRVREANVYSEIVPHTFTTEQLLAKNPAAIILSGGPSSVYAEGAPSVGADLF
EAGVPVFGICYGFQAMANALGGKVAQTGLREYGATEALVVGDARSILDGVPSSQNTWMSHGDSVHEAPEGFEVLASTAGA
PVAAFANDEKRLYGVQWHPEVKHSVHGQHVLENFLFKGAGLSPNWTTGNILEEQVDRIRQQIGDSKVICGLSGGVDSAVA
AALVQRAVGDQLTCVFVDHGLLREGEAEQVERDFVAATGVNLYVANEQERFQSALAGVSDPETKRKIIGREFIRAFEEAE
RAIIAQAAAEGEKIKFLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPEDLQFELVEPLRALFKDEVRAVGAQLGLPQEI
VGRQPFPGPGLGIRIVGEVTKERLDLLRKADAIARAELTAAGLDNDVWQMPVVLLADVRSVGVQGDGRTYGHPIVLRPVS
SEDAMTADWSRLPYDLLARISNRITNEVDGVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-170 72
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-129 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-129 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-129 50