Gene Information

Name : leuS (AAur_2246)
Accession : YP_947987.1
Strain : Arthrobacter aurescens TC1
Genome accession: NC_008711
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2471002 - 2473599 bp
Length : 2598 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGTGTCCGGGGGTATCCGGGACCGCAGCAGGAGGGAAAACCGCCATCGAAGAACAGAAGAGGGCAGCAGTGAGCGTTAA
GCCGGAGACAGAGACCGGGACAGCACAAACAGCCGCAGCCGAAGCGCCTGAAGAAGGCGTCTACAGCTTCGCTGCGATGG
AAGCCAAGTGGCCGCAGGTCTGGGAAGACCTTAAGGTCTTCACTCCCGCCGACGACGGTTCCCGGGAACGCCGCTACGTG
CTGGACATGTTCCCTTACCCCTCCGGCGATCTGCACATGGGCCACGCCGAAGCGTTCGCGATGGGTGACGTCGTAGCGCG
TTACCTGCGTCAGAAGGGCTTCGACGTTCTGCACCCCATCGGCTGGGACTCTTTCGGCCTCCCCGCTGAGAACGCTGCGA
TCAAACGCAATGCCCACCCCAGCGAGTGGACCTACGCGAACATCGATACGCAGGCAGCGTCGTTCAAGCGCTACGCAATC
TCTGCCGACTGGTCCCGCCGCCTCCACACCTCGGATCCCGAGTACTACCGGTGGACGCAGTGGCTGTTCAAGCGCTTCTA
CGAGCGTGGCCTGGCCTACCGCAAGGATTCGCCCGTCAACTGGTGCCCCAAGGACCTCACCGTGCTCGCGAACGAGCAGG
TAGTTAACGGTGCCTGCGAACGCTGCGGCACGCCTGTCACCAAGAAGTCCCTGAACCAGTGGTACTTCAAGATCACTGAC
TACGCCGACCGCCTGCTGGAAGACATGGACCAGCTCCAAGGTCACTGGCCCGAGCGCGTTCTGGCCATGCAACGCAACTG
GATCGGCCGCTCCGAAGGCGCCCACGTGCGGTTCGTCATTGAAGCCACCGCGGACCGTGCCGAGCGCGAAGTCACCGTAT
TCACCACCCGTCCGGACACCCTCTACGGTGCAACGTTCTTCGTTGTCGCAGCCGACGCGCATTTGGCGCTGGACCTGGTT
ACCCCGGAACAGCACGATGAACTCATGGCCTACCGCGAGAAGGTCAAGGCGCTCTCCGAAATCGAACGCCAGTCCACCGA
ACGCGAGAAAACCGGCGTCTTCACCGGCCGCTACGCCATCAACCCGCTCAACGGCGAAAAGCTCCCCGTCTGGGCTGCTG
ACTACGTTCTGGCCGACTACGGCACCGGCGCCATCATGGCCGTCCCGGCACACGACCAGCGGGACCTCGACTTCGCCAAG
ACCTTCGGACTCCCTGTCCGTGCGGTCCTGGACACCGGTGACGAAGACCCGGCAGAGACGGGTGTCGCCACCGCGGGAGA
AGGCACGCTCAAAAACTCCGGCGAGCTGGACGGGCTGTCCAAGTCCGAAGGCATTCCCGCAGCGATCGAGATCCTCGAGA
AACTGGGAACCGGCGAGAAGTTCGTCAACTTCCGGTTGCGGGACTGGCTGCTGAGCCGCCAGCGCTTCTGGGGTACCCCC
ATCCCCATCATTCACTGCGGTGAATGTGGCGAAGTGCCCGTCCCCGATGACCAGCTACCCGTCAGGTTGCCGGACGACCT
GCGCGGTGAGGCGTTGTCGCCGAAGGGGACCTCCCCGCTGGCCGCCGCAGTCGAATGGGTCAACGTCGAGTGCCCTAACT
GTGGACGCGCCGCGCAGCGGGACACCGACACCATGGATACCTTCGTGGATTCGTCCTGGTACTTCCTGCGCTTCGTTTCC
CCGGACTACACCGAAGGCCCGTTCGATCCCGAAAAGATCAACAACTGGATGCCGGTGGGGCAGTACGTGGGCGGAGTGGA
GCACGCCATCCTTCACCTGCTCTACGCACGTTTCTTCACCAAGGTCATCAAGGACATCGGCCTGATCGAAGCCAACGAAC
CGTTCTCCGCACTCCTCAACCAGGGCCAGGTGCTCAACGGCGGCAAGGCCATGAGCAAGTCCCTCGGCAATGGCGTGGAT
TTGGGCGAGCAGTTGGACAAGTTCGGCGTCGACGCCGTTCGCCTCACCATGGTCTTCGCCTCCCCACCTGAGGACGACGT
CGACTGGGCGGACGTTTCGCCGTCCGGTTCGGCCAAATTCCTGGCCCGCGCCTGGCGCCTCGGCCAGGACGTCAGCAGCG
AACCGGGCGTTGATCCGGCCACTGGTGACCGTGCCCTGCGCACCGTGACCCACAAGACCATCGCCGATGCCGCTGAACTG
CTGGACAACAACAAGTTCAACGTCGTGGTTGCCCGCCTGATGGAGTTGGTCAATGCCACGCGCAAAACCATCGATTCGGG
GGCAGGCGCCGCAGATCCGGCTGTTCGTGAAGCGGTGGAAGCCGTAGCCGTGATCCTGAGCCTCTTTGCGCCCTACACGG
CTGAGGACTTGTGGAACACGCTCGGTCACCCGGCTTCCGTTGCGAATGCAGGCTGGCCGAAGCACGACGATGCACTGCTG
GTACAGGACACCGTGACCGCTGTGGTCCAGGTGCAGGGCAAGGTTCGCGACCGTCTGGAAGTTTCGCCGGACATCACCGA
GGACGCGCTGCGTGAGCTCGCCCTGGCCTCGGAGAACGTCCAGCGTGCCTTGGACGGCCGCGGCATCCGTACAGTCATCG
TGCGGGCACCTAAACTGGTGAACATCGTTCCTGCCTAG

Protein sequence :
MCPGVSGTAAGGKTAIEEQKRAAVSVKPETETGTAQTAAAEAPEEGVYSFAAMEAKWPQVWEDLKVFTPADDGSRERRYV
LDMFPYPSGDLHMGHAEAFAMGDVVARYLRQKGFDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYANIDTQAASFKRYAI
SADWSRRLHTSDPEYYRWTQWLFKRFYERGLAYRKDSPVNWCPKDLTVLANEQVVNGACERCGTPVTKKSLNQWYFKITD
YADRLLEDMDQLQGHWPERVLAMQRNWIGRSEGAHVRFVIEATADRAEREVTVFTTRPDTLYGATFFVVAADAHLALDLV
TPEQHDELMAYREKVKALSEIERQSTEREKTGVFTGRYAINPLNGEKLPVWAADYVLADYGTGAIMAVPAHDQRDLDFAK
TFGLPVRAVLDTGDEDPAETGVATAGEGTLKNSGELDGLSKSEGIPAAIEILEKLGTGEKFVNFRLRDWLLSRQRFWGTP
IPIIHCGECGEVPVPDDQLPVRLPDDLRGEALSPKGTSPLAAAVEWVNVECPNCGRAAQRDTDTMDTFVDSSWYFLRFVS
PDYTEGPFDPEKINNWMPVGQYVGGVEHAILHLLYARFFTKVIKDIGLIEANEPFSALLNQGQVLNGGKAMSKSLGNGVD
LGEQLDKFGVDAVRLTMVFASPPEDDVDWADVSPSGSAKFLARAWRLGQDVSSEPGVDPATGDRALRTVTHKTIADAAEL
LDNNKFNVVVARLMELVNATRKTIDSGAGAADPAVREAVEAVAVILSLFAPYTAEDLWNTLGHPASVANAGWPKHDDALL
VQDTVTAVVQVQGKVRDRLEVSPDITEDALRELALASENVQRALDGRGIRTVIVRAPKLVNIVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-154 42