Gene Information

Name : BT0348 (BT0348)
Accession : YP_945352.1
Strain : Borrelia turicatae 91E135
Genome accession: NC_008710
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 359019 - 360452 bp
Length : 1434 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATACAAAAATTAACAAAAATAGTAGCAACAATATCTGACCTCAGATGTGATCCAGAACACATAAAAGAGTTATATGA
AGCAGGAGTAAATGTAATAAGACTTAATACTGCTCATCAATCTCATGACGATGCAATAAGAGTAATAAACAATGTTAGAA
AAGTTTCAAATAAAATAGCATTAATGATCGATACAAAAGGACCAGAAGTTAGAACAGCTAATATTGAAAATCCTATTACC
GTTAAGATAGGAGACAAAATAATAATCTCAACATCACCTATCAATGAGTCTAATGCATTGCAAACCAACTATGATGGATT
TGTAAATGAAGTCCCAAATGGCTCGACAATCCTTATTGATGATGGCGAACTTGAAATGACTGTTATTGAAAAACTCACAG
ATAGATTAATCTGCAAAGTTAAAAACGACGGACAAATCAAAAACAAAAAATCAATTAATACACCGGGAATTTCACTTAAA
CTACAATCTGTCACTGAAAAAGATAAGGGATTTATTGAACTTGCAGCAAAACAAAATATTGATTTTATTGCCCATTCATT
CGTAAGACATGCAAAAGATATTCAAGACGTTAAAGATATATTAAATGCTGCTGGAAATCCAGACGTCAAAATTATTGCCA
AAGTTGAAAATCAAGAAGGAATTGATAATATTGAAGAAATTGCAAAAGCTTCCTATGGAATTATGGTTGCAAGAGGCGAT
ATGGGAGTTGAAATACCAGCTGAAGATGTTCCTTTAGCACAAATTAAAATAACAAAAACCTGCATTAAATATGGAGTACC
TGTAATTACTGCAACACAAATGTTGCACACAATGATTGAAAATCCAAGACCTACAAGAGCAGAAGTATCTGATGTAGCCA
ATGCAATTCTAAATGGTACAGATGCCATCATGCTATCTGGAGAGACAGCTTATGGCAAATACCCAATTGAAGCTGTTAAG
ATGATGACCAAAATTGCTATAGAAGTTGAAAAATATAGAGAAAAAACACTATTTCAAGATGAAATTTTCCACAGCAAAAG
GATCATAAGAAACTATATTATTAAATGTGCAATTGATGCAATCAAAATAATGCCTGTTAAAGCCATTATTGTTGATTCAC
TTAAAGGAAGAACCGCAAGAATAATGGCAACATACAGAGCAAGTGTACCTCTATTTATTACAACAAATAATGAAAGGATA
GCAAGAGAATTATCACTCTCTTATGGTGTTTATGCTAATCTGGTTGATCATAACTTCAAGGCAACAACTGAATTTGTAGT
AACCTCTCTTGAAATGCTTAAAACACAAAAAGTAGTTCAAGATTCAGATATTGTAGTAATTATCTCCGGAAATCCAAATA
GAGATACTAATAAAGGTACGGAATTTATGGAAATAAATACAGTAGAAGAAGCAATTAAAGGACACAACAGATAA

Protein sequence :
MIQKLTKIVATISDLRCDPEHIKELYEAGVNVIRLNTAHQSHDDAIRVINNVRKVSNKIALMIDTKGPEVRTANIENPIT
VKIGDKIIISTSPINESNALQTNYDGFVNEVPNGSTILIDDGELEMTVIEKLTDRLICKVKNDGQIKNKKSINTPGISLK
LQSVTEKDKGFIELAAKQNIDFIAHSFVRHAKDIQDVKDILNAAGNPDVKIIAKVENQEGIDNIEEIAKASYGIMVARGD
MGVEIPAEDVPLAQIKITKTCIKYGVPVITATQMLHTMIENPRPTRAEVSDVANAILNGTDAIMLSGETAYGKYPIEAVK
MMTKIAIEVEKYREKTLFQDEIFHSKRIIRNYIIKCAIDAIKIMPVKAIIVDSLKGRTARIMATYRASVPLFITTNNERI
ARELSLSYGVYANLVDHNFKATTEFVVTSLEMLKTQKVVQDSDIVVIISGNPNRDTNKGTEFMEINTVEEAIKGHNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-69 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-69 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-69 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BT0348 YP_945352.1 pyruvate kinase VFG0479 Protein 6e-70 41