Gene Information

Name : BT0288 (BT0288)
Accession : YP_945296.1
Strain : Borrelia turicatae 91E135
Genome accession: NC_008710
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 299447 - 300757 bp
Length : 1311 bp
Strand : -
Note : -

DNA sequence :
TTGATGGACATCTTTTTTGAAGGTTATTCAAAAATGTTGGATGATGTTGAGCCTATATCTCTTATTGGTAAAGTAAGGAA
GATTAAAGGTCTCTTAGTAGAAAGTTTGGGTCCAAAATGTGGTATTGGTGATTTATGTTTAATAGAGCAGAGAAGTGGTA
AGAAAATATATGCTGAAGTTTTAGGTTTAAATGGATCGTTTGTTAATCTTATGGCTTATGAAGGATTTGATGGAATTGAG
ATTGGCGATCAAGTTTGCTCTTTAGGTAAAAAGCTTCAGATTAATCTTAGCGATGAATTACTTGGTAGGGTGATTGATTC
TCTTGGTAGACCTATTGATAATAAGGGGCAGTTTTTTTGTAATTATTATAAAGAATTAAGTTTTAGTAATATTAATCCTT
TAAGTAGAGGTGTTTTTTCTGAGCAAATAGTTACTGGTGTTAAAGTTCTTGATGGGTTTTTACCAGTTGCAAAGGGACAA
CGTGTAGGCATTTTCTCAGGTGCGGGTGTTGGTAAGTCTACTTTGCTTGGTATGATTGCTAAAAATTCTAAGGCAGATGT
TAATGTTATTGCCTTTATTGGTGAGAGAGGCCGTGAGCTTAATGAGTTTATTAAATATGATCTTGGAGAAGAATGCTTTA
AGAGAAGTGTTTTGATTGTTTCAACCTCTGATGCATCTCCTATCGCAAGATATAAAGGGGCTTATACCGCAACATTAATA
GCTGAATATTTTAGAGATTGTGGAATGGATGTTATGTTGCTGTTTGATTCAATTACAAGATTTGCAAATGCTAAAAGGGA
AATTAGTCTTTCTATGGGAGAGCCACCTGCTACTAAAGGATATCCCCCTTCTGTTTTTGTAGAAATTCCTATTTTGCTTG
AGCGTTCAGGACTTAATTCTAAGGGTAGTATTACAGGGTTTTATACTGTGCTTGTTGAGGGTGATGATTTTACAGAACCG
ATAGCTGATAATATGAAAGCTGTTTTAGATGGGCACATTATTTTGGATAGAGATTTATCTGATAGAGGGATTTATCCTTC
TGTAAATATTTTGAGTTCTACTTCAAGATCTCTTCATAGAATAGTAAATTTTGAAAAACAAAAATTGATATCTAAAATTA
GGAATTTATTATCAATTTATAAAAGTTATGAAGATTTAATTAAGACGGGAATTTATATTAAAGGTTCTAATAAAGAAGTT
GATTTGGCAGTTGCAAAATATCCAAAGATTATTGATTTTTTGTCTCAAGGAATACAAGAGGAGTTTGATTTTGAAAATTT
GGATAGTGAATTGAGAGAAATATTAGCTTGA

Protein sequence :
MMDIFFEGYSKMLDDVEPISLIGKVRKIKGLLVESLGPKCGIGDLCLIEQRSGKKIYAEVLGLNGSFVNLMAYEGFDGIE
IGDQVCSLGKKLQINLSDELLGRVIDSLGRPIDNKGQFFCNYYKELSFSNINPLSRGVFSEQIVTGVKVLDGFLPVAKGQ
RVGIFSGAGVGKSTLLGMIAKNSKADVNVIAFIGERGRELNEFIKYDLGEECFKRSVLIVSTSDASPIARYKGAYTATLI
AEYFRDCGMDVMLLFDSITRFANAKREISLSMGEPPATKGYPPSVFVEIPILLERSGLNSKGSITGFYTVLVEGDDFTEP
IADNMKAVLDGHIILDRDLSDRGIYPSVNILSSTSRSLHRIVNFEKQKLISKIRNLLSIYKSYEDLIKTGIYIKGSNKEV
DLAVAKYPKIIDFLSQGIQEEFDFENLDSELREILA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-79 44
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-80 44
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-80 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-79 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-79 43
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-85 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-85 43
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-86 43
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-86 43
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-86 43
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-85 43
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-86 43
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-86 43
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-86 43
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-79 42
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-79 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-62 41
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-66 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-65 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-65 41
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-70 41
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-70 41
unnamed AAL06369.1 EscN Virulence LEE Protein 6e-72 41
escN AAC38383.1 EscN Virulence LEE Protein 4e-72 41
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-72 41
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-72 41
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-72 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-72 41
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-72 41
escN AAC31513.1 L0034 Virulence LEE Protein 4e-72 41
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-72 41
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG2144 Protein 4e-93 46
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG0390 Protein 3e-83 44
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG2499 Protein 7e-79 44
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG1254 Protein 1e-83 43
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG0515 Protein 7e-80 43
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG0048 Protein 4e-82 43
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG2331 Protein 5e-73 42
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG0192 Protein 3e-84 42
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG0812 Protein 2e-72 41
BT0288 YP_945296.1 flagellum-specific ATP synthase VFG0730 Protein 2e-72 41