Gene Information

Name : guaA (Ping_2949)
Accession : YP_944250.1
Strain : Psychromonas ingrahamii 37
Genome accession: NC_008709
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3634203 - 3635783 bp
Length : 1581 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGACAAAAACATTCATGAACAGCGAATTCTGATTTTAGATTTCGGTTCTCAGTACACCCAATTAATCGCGCGTCGCAT
TCGTGAAATAGGTGTTTACTGTGAACTTTGGAGCTGGGATGTTGATGAGCAGGATATTAAAGATTTTGCTCCTAACGGCA
TTATTTTAGCGGGTGGCCCTGAAAGTGTCACCGCTGAAGGTTCTCCTCGTGCACCTGAATATGTCTTTACTGCGGGGGTT
CCTGTATTAGGTATCTGCTACGGTATGCAGACTATGTCCGAGCAACTCGGTGGATCGGTCATTAAAGGTGAAGGCGAAGG
CGAATTTGGTTACGCACAGATTGAAGTCAAAGGGGCCTCTGAACTATTCAAACTGATTGAAGATGCGGTTGCACAAAATG
GTAATGCTTTATTAGATGTTTGGATGAGTCATGGCGATAAAGTGTCCGCTATTCCGGCCGGTTTTACGACTATTGCTAAT
ACTGCTACCTGTCAGTTTGCTGCTATTGCCAATGAAGAAAAACGTTTTTATGGTGTACAGTTTCATCCGGAAGTCACTCA
TACTCGCCAGGGTGAGCGTATGTTACGCCACTTTGTGATGGATATTTGTGGCTGTGAGACGCTTTGGACATCAAGTTCAA
TCATCGAAGATGCGGTTGCGCGCATGAAAGCGCAGATTGGTGATGATGAAGTTATTCTTGGTCTTTCCGGCGGTGTTGAT
TCCTCCGTTGTGGCAATGTTATTACAACGCGCTATTGGTGATAAACTTACCTGTGTCTTTGTTGATAACGGTTTACTGCG
TTTAAATGAAGGCCAGCAGGTGATGGATATGTTTGGTGATCACTTCGGATTAAAAATCATTCATGTTAATGCAGAACACC
GTTTCTTGGAGCAGATGGCTGGCGAAAGCGATCCTGAAGCGAAACGTAAAATCATTGGCCGTGTTTTTGTCGAAATTTTC
GATGAAGAATCTAAAAAACTTAAAAATGCCAAATGGTTAGCGCAGGGTACTATCTACCCCGATGTAATCGAATCAGCAGG
CTCTAAAACGGGTAAAGCACAGGTGATTAAATCTCACCATAATGTGGGCGGATTACCCGATGATATGGAAATGGGTCTGG
TTGAACCACTGCGTGAATTGTTTAAAGATGAAGTACGTAAAATCGGCTTAGAGTTAGGTCTACCTTATGAGATGCTTTAC
CGTCATCCTTTCCCGGGGCCGGGTCTAGGCGTACGTGTGCTGGGTGAAGTGAAGAAAGAGTACTGCGATTTACTGCGCCG
CGCCGATGCGATATTTATTGAAGAGTTACATAAAGCGGATCTTTACCATAAAGTCAGTCAAGCCTTTGTGGTCTTCCTGC
CGGTACGCTCCGTGGGTGTAATGGGCGATTGTCGTAAATACGATTGGGTTGTGTCCCTGCGTTGTGTGGAAACAATCGAC
TTTATGACCGCGCGTTGGTCACATCTTCCTTATGATTTAATCGGTCATGTATCAAATCGTATCATCAATGAAATTGATGG
TATTTCCCGTGTAGTGTACGATGTTTCAGGTAAACCGCCTGCAACCATCGAGTGGGAGTAG

Protein sequence :
MDKNIHEQRILILDFGSQYTQLIARRIREIGVYCELWSWDVDEQDIKDFAPNGIILAGGPESVTAEGSPRAPEYVFTAGV
PVLGICYGMQTMSEQLGGSVIKGEGEGEFGYAQIEVKGASELFKLIEDAVAQNGNALLDVWMSHGDKVSAIPAGFTTIAN
TATCQFAAIANEEKRFYGVQFHPEVTHTRQGERMLRHFVMDICGCETLWTSSSIIEDAVARMKAQIGDDEVILGLSGGVD
SSVVAMLLQRAIGDKLTCVFVDNGLLRLNEGQQVMDMFGDHFGLKIIHVNAEHRFLEQMAGESDPEAKRKIIGRVFVEIF
DEESKKLKNAKWLAQGTIYPDVIESAGSKTGKAQVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYEMLY
RHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYHKVSQAFVVFLPVRSVGVMGDCRKYDWVVSLRCVETID
FMTARWSHLPYDLIGHVSNRIINEIDGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-129 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-129 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-109 47