Gene Information

Name : Mkms_4842 (Mkms_4842)
Accession : YP_940822.1
Strain : Mycobacterium sp. KMS
Genome accession: NC_008705
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5069435 - 5071978 bp
Length : 2544 bp
Strand : -
Note : PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mmc:Mmcs_4756 ATPase AAA-2

DNA sequence :
ATGTTCGAACGTTTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCTCAAGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGACTCATTCACGAGGGTGAGGGCGTAGCGGCCAAGTCTCTCGAGTCGCTGGGCA
TCTCGCTGGAAGGCGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCCGGTCACATCCCCTTC
ACCCCGCGCGCCAAGAAGGTGCTCGAGCTGTCCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGGTTGATCCGTGAGGGCGAAGGCGTCGCCGCTCAGGTCCTCGTGAAGCTCGGCGCCGAACTGACGCGCG
TGCGCCAGCAGGTCATCCAGCTGCTCAGCGGCTACCAGGGCAAGGAGTCCGCGGAGGCCGGCACCGGCGGCCGCGGCGGC
GAATCCGGCAACCCCTCGACCTCGCTGGTGCTCGACCAGTTCGGCCGCAACCTGACCGCCGCCGCGATGGAGGGCAAGCT
CGACCCCGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTCC
TCATCGGAGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAAGGGCTCGCCCAGGCGATCGTGCACGGCGACGTGCCCGAG
ACGCTGAAGGACAAGCAGCTCTACACCCTCGACCTCGGGTCGCTGGTCGCCGGCAGCCGCTACCGTGGTGACTTCGAGGA
GCGCCTGAAGAAGGTCCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGTTGCACACGCTCGTCG
GCGCGGGTGCCGCCGAGGGTGCGATCGACGCGGCCAGCATCCTGAAGCCGAAGCTAGCCCGCGGTGAGCTGCAGACCATC
GGTGCGACCACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCACTGGAACGCCGCTTCCAGCCCGTTCAGGT
CGGCGAGCCGACGGTTGCGCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGCTACGAGGCGCACCACCGCGTGTCGA
TCACCGACGGCGCGATCGCGGCGGCGGCCACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCCGGTGCGCGCATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAATTCGACGAGAA
GATCGCCGATGCGCGCCGGGAGAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGAGCCTGCGTGACAAGG
AGAAGACCCTCGTCGCGCAGCGTGCCGAGCGTGAGAAGCAGTGGCGCTCGGGTGATCTGGATGTCGTGGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTCGGCAACTGGACCGGCATCCCCGTGTTCAAGCTGACCGAGGAGGAGACCACTCGGCT
GCTGCGCATGGAGGATGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCGGTCTCGAAGGCGATCCGCC
GCACCCGCGCCGGGCTGAAGGACCCCAAGCGTCCGTCGGGTTCGTTCATCTTCGCCGGCCCGTCAGGTGTCGGTAAGACC
GAGCTCTCGAAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCGTCGCGGCTGTTCGGTGCCCCTCCGGGCTACGTCGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGCAAGCCGTTCTCGGTTGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACAGCCTCCTGCAG
GTCCTCGAGGACGGCCGTCTCACCGACGGTCAGGGTCGCACGGTCGACTTCAAGAACACCGTGCTGATCTTCACGTCCAA
CCTCGGCACCTCCGACATCAGCAAGGCGGTCGGGCTGGGCTTCACCCAGGGCGGCGGCGAGAACAACTACGAGCGGATGA
AGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTGTTCCAC
CAGCTCACGCAGGACGAGATCATCAAGATGGTCGACCTGATGATCGGCCGGGTCGGCAATCAGCTGCGGGCCAAGGACAT
GACGATGGAGCTCACCGACAAGGCGAAGTCTCTGCTGGCCAAGCGTGGCTTCGACCCGGTGTTGGGTGCCCGTCCGTTGC
GTCGGACCATCCAGCGCGAGATCGAGGACCAGCTGTCGGAGAAGATCCTGTTCGAGGAGATCGGCCCCGGTCAGCTGATC
ACCGTGGACGTCGAGAACTGGGACGGCCAGGGAGCGGGCGAGGACGCGAAGTTCACCTTCAGCGGTGGTCCGAAGCGGTC
CGAGCCGGTCGAGCCGGATCTGGCGCAGGCCGGCGCTGCCGGTGCGCCGAGCGCAGCCGAGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGG
ESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQLI
TVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAAGAPSAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 82

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mkms_4842 YP_940822.1 ATPase VFG0079 Protein 0.0 60
Mkms_4842 YP_940822.1 ATPase VFG0080 Protein 1e-142 51