Gene Information

Name : Mkms_0451 (Mkms_0451)
Accession : YP_936457.1
Strain : Mycobacterium sp. KMS
Genome accession: NC_008705
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.-
Position : 496194 - 497480 bp
Length : 1287 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGGACGACGTGACCATGCCTCAGACGCCGGCCGAGCGGACCTGGCACCCCCAGGGCCACCAGCCGCGGCCCCGTACGTT
CACGCAGTCGTCGAAGCTGCAGGACGTCCTCTACGAGATCCGCGGCCCGGTACACGAGCACGCGTCGCGGCTGGAGGCCG
AGGGCCACCGCATCCTCAAGCTCAACATCGGCAACCCGGCGCCGTTCGGCTTCGAGGCACCCGATGTGATCATGCGCGAC
ATCATCCAGGCGCTGCCGTACGCGCAGGGCTACTCGGACTCCAAGGGCATCATGCCCGCGCGCCGGGCGGTGTTCACCCG
CTACGAACTCGTCGACGGGTTCCCGCGCTTCGACGTCGACGACGTGTTCCTCGGCAACGGGGCCTCCGAGCTCATCCAGA
TGGTGCTGCAGGCACTGCTGGACAACGGCGATCAGGTGCTGATCCCGGCGCCGGACTATCCGCTGTGGACGGCGTGCACC
TCGCTGGCGGGCGGCACCCCGGTGCACTACCTGTGTGACGAGACGCAGGGCTGGAATCCCGACGTCGCCGACATCGAGTC
GAAGATCACCGACCGCACCAAGGCGATCGTCGTCATCAACCCGAACAACCCGACCGGCGCGGTGTACAGCCGCGAGACGC
TGGAGCGGATCGCCGATCTCGCCCGGAAACACCAGCTGCTGCTGCTGGCCGACGAGATCTACGACAAGATCCTCTACGAC
GATGCCAAGCACATCTCGCTGGCCTCGGTCGCGCCCGACGTGTTGACCCTGACGTTCAACGGGCTGTCGAAGGCCTACCG
GGTGGCGGGTTACCGCTCGGGCTGGCTGGTGATCACCGGACCCAAGGAGCACGCCAGCAGCTTCATCGAGGGCATCAGCC
TGCTGGCCAACATGCGGTTGTGCCCGAATGTGCCTGCACAGCATGCGATTCAGGTGGCGCTCGGCGGCCATCAGAGCATC
GACGATCTGGTGTTGCCCGGCGGGCGGTTGCTCGAGCAGCGCGACGTGGCCTGGGAGAAGCTCAACGAGATTCCCGGCGT
CTCGTGCGTGAAGCCGGCCGGCGCGCTGTACGCGTTCCCGCGGCTGGATCCCGAGGTCTACGAGATCCACGACGACGAGC
TGCTGGTGCTCGACCTGCTGCTGCAGGAAAAAATCCTGGTTGTGCAGGGCACCGGGTTCAACTGGCCGACACCGGATCAC
CTGCGCATCGTCACGCTGCCGTGGGCTCGTGACCTGGCCAACGCCATCGAGCGTCTCGGCAACTTCCTGGTCAGCTACCG
GCAGTAG

Protein sequence :
MDDVTMPQTPAERTWHPQGHQPRPRTFTQSSKLQDVLYEIRGPVHEHASRLEAEGHRILKLNIGNPAPFGFEAPDVIMRD
IIQALPYAQGYSDSKGIMPARRAVFTRYELVDGFPRFDVDDVFLGNGASELIQMVLQALLDNGDQVLIPAPDYPLWTACT
SLAGGTPVHYLCDETQGWNPDVADIESKITDRTKAIVVINPNNPTGAVYSRETLERIADLARKHQLLLLADEIYDKILYD
DAKHISLASVAPDVLTLTFNGLSKAYRVAGYRSGWLVITGPKEHASSFIEGISLLANMRLCPNVPAQHAIQVALGGHQSI
DDLVLPGGRLLEQRDVAWEKLNEIPGVSCVKPAGALYAFPRLDPEVYEIHDDELLVLDLLLQEKILVVQGTGFNWPTPDH
LRIVTLPWARDLANAIERLGNFLVSYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 5e-138 73
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 5e-138 73
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 5e-138 73
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 5e-138 73