Gene Information

Name : Mkms_4419 (Mkms_4419)
Accession : YP_940400.1
Strain : Mycobacterium sp. KMS
Genome accession: NC_008705
Putative virulence/resistance : Unknown
Product : succinate-semialdehyde dehydrogenase (NAD(P)(+))
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.16
Position : 4648300 - 4649748 bp
Length : 1449 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4333 succinate-semialdehyde dehydrogenase (NAD(P)+)

DNA sequence :
ATGGACACCACCGCACTGTTGAAGTCAGTTCCCACCGGACTGTGGATCGGTGGTGAAGAACGCGAGGCGAAGTCGACGTT
CAACGTGTTGGACCCCAGTAGCGACGAGGTGCTGGTGGCCGTCGGCGACGCGACGGCCGAGGACGCGGTCGCCGCGCTCG
ACGCCGCCTGCGCGGTGCAGGCCGAATGGGCGGCCACGCCCGCGCGGAAACGCGGCGAGATCCTGCGGTCGGTCTTCGAG
ACGCTCACCGACCGCGCCGACGACATCGCCGCGCTGATGACCCTCGAGATGGGCAAGGTGCTCGCCGAGAGTAAGGGTGA
GGTCACCTACGGCGCCGAGTTCTTCCGCTGGTTCGCCGAAGAGGCCGTCCGCATCGGCGGCAGGTACACGCCGAGCCCGG
CCGGCACCGGCCGCATCATCGTCACCAAACAGCCCGTCGGGCCGTGTTACGCGATCACCCCGTGGAACTTCCCGCTGGCC
ATGGGCACCCGCAAGATGGGCCCGGCGTTCGCCGCGGGTTGCACGATGATCGTCAAACCCGCGCAGGAAACCCCGCTGAC
CATGCTGTACCTGGCCAAGCTGATGGCCGAGGCGGGGCTGCCCAAGGGCGTGCTGTCGGTGCTGCCGACCAGCAGCCCCG
GACCCGTCACCGAGGCGCTCGTCGACGACGGCCGACTGCGCAAGCTGACCTTCACCGGTTCCACGGGGGTGGGCAAGTCG
CTGGTGAAACAGTCCGCCGACAAGCTGCTGCGCACGTCGATGGAGCTCGGCGGCAACGCGCCGTTCATCGTGTTCGACGA
CGCCGACGTCGATGCCGCGGTCGACGGCGCGATGCTGGCCAAGATGCGCAACGGCGGTGAGGCCTGCACCGCGGCCAACC
GCTTCCACGTGGCCAACTCCGTGCGCGAGGAGTTCACCGAGAAGCTGGTCAAGCGGATGAGCGAGGTGACGCTCGGCAAC
GGCCTCGACGAATCCGCCACGCTCGGCCCGCTGATCAACAACAAGCAGCTGCAGAAGGTGACCGAACTGGTCTCCGACGC
GGTCTCGCGCGGCGCGACCGTCGCCGTCGGCGGCGTCGCCCCCGGCGGGCCCGGCAACTTCTACCCGGCCACGGTGCTCG
CCGACGTGCCGGCCGACGCCCGCATCCTCAAGGAGGAGGTGTTCGGGCCCGTCGCCCCGATCACCGGATTCGACTCCGAG
GAGGAGGGCGTCGCCGCGGCCAACGACACCGAATACGGGCTGGCCGCCTACGTGTACACCCGGTCGCTGGACCGCGCGCT
GCGCGTCGCCGAGGCCATCGAATCCGGGATGGTCGGCATCAACCGCGGCGTGATCAGCGACGCCGCCGCGCCGTTCGGCG
GTATCAAGGAGTCCGGCTTCGGCCGCGAGGGCGGCACCGAGGGCATCGAGGAGTACCTCGACACGAAGTACATCGCGTTG
ACGAAGTAG

Protein sequence :
MDTTALLKSVPTGLWIGGEEREAKSTFNVLDPSSDEVLVAVGDATAEDAVAALDAACAVQAEWAATPARKRGEILRSVFE
TLTDRADDIAALMTLEMGKVLAESKGEVTYGAEFFRWFAEEAVRIGGRYTPSPAGTGRIIVTKQPVGPCYAITPWNFPLA
MGTRKMGPAFAAGCTMIVKPAQETPLTMLYLAKLMAEAGLPKGVLSVLPTSSPGPVTEALVDDGRLRKLTFTGSTGVGKS
LVKQSADKLLRTSMELGGNAPFIVFDDADVDAAVDGAMLAKMRNGGEACTAANRFHVANSVREEFTEKLVKRMSEVTLGN
GLDESATLGPLINNKQLQKVTELVSDAVSRGATVAVGGVAPGGPGNFYPATVLADVPADARILKEEVFGPVAPITGFDSE
EEGVAAANDTEYGLAAYVYTRSLDRALRVAEAIESGMVGINRGVISDAAAPFGGIKESGFGREGGTEGIEEYLDTKYIAL
TK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1509 YP_001800903.1 NAD-dependent aldehyde dehydrogenase Not tested Not named Protein 4e-98 49
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 4e-89 48