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Name : Mkms_4221 (Mkms_4221) Accession : YP_940203.1 Strain : Mycobacterium sp. KMS Genome accession: NC_008705 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 4.4.1.1 Position : 4446994 - 4448172 bp Length : 1179 bp Strand : - Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine DNA sequence : ATGACTGAACAGCGCAGCGCCCACGGACCCGCCCACGGACTCGCCACTGGACTCGCCACGAAGGCCATCCACGCCGGGTA CGCCCCCGACCCCCGCACCGGTGCGGTCAACACGCCGATCTACGCCAGCTCGACCTTCGCCCAGGACGGTGTCGGAGGGC TGCGGGGCGGCTTCGAGTACGCCCGCACCGGCAACCCGACGCGGCAGTCCCTGGAGTCGGCGCTGGCCGCGGTGGAGGAA GCCGGGTACGGCCGGGCCTTCGCCTCCGGGATGGCCGCCACCGACTGTGCGTTGCGCGCGGTGCTGCGCCCCGGTGACCA TCTCGTCATCCCGGACGACGCCTACGGCGGCACGTTCCGGCTGATCGACAAGGTGTTCTCCCAGTGGGGCATCAGCTACA CGGCGGTCGCGCTGTCGGACCTCGACGCCGTCCGGGCGGCGATCACCCCGCAGACCAAGATGATCTGGGTCGAGACGCCG ACCAACCCGCTGCTGTCGATCGCCGACATCGCCGGTATCGCAGGCATCGCGGCCGAATCGGGGCTGAAGGTGTTGGTGGA CAACACCTTTGCCTCGCCCGCGTTACAGCAGCCGTTGCTGCTCGGCGCGGACATCGTGTTGCACTCCACCACGAAGTACA TCGGCGGACACTCCGACGTGGTCGGCGGCGCGCTGCTGACCAACGACGAGGAACTCGACACGGCGTTCGCCTTCCTGCAG AACGGATCGGGCGCCGTCCCAGGACCGTTCGACGCCTACCTCACCCTGCGCGGACTCAAGACGCTGGTGGTGCGGATGCA GCGACACAGCGAGAACGCTGCGGCGGTCGCCGAATTCCTCGACGGCCACCCGGCGATCGACACGGTGCTCTATCCCGGTC TGCCCAGCCATCCCGGCCACGACGTGGCCGCCAAGCAGATGAGCGGGTTCGGCGGCATGGTGTCGGTGCGGCTACACGGC GGGCCCAAGGCGGCTCGCGAATTCTGCGCCCGCACAGGCATTTTCATCCTCGCCGAATCGCTGGGCGGGGTGGAGTCGCT GATCGAGCATCCGGGTGCGATGACGCACGCGTCCACCGCCGGATCCCAACTCGAGGTGCCCGAGGATCTGGTGCGGCTGT CGGTCGGCATCGAGGACCGCGCGGATCTGATCGCCGACCTGGAGCAGGCGCTAGCCTAA Protein sequence : MTEQRSAHGPAHGLATGLATKAIHAGYAPDPRTGAVNTPIYASSTFAQDGVGGLRGGFEYARTGNPTRQSLESALAAVEE AGYGRAFASGMAATDCALRAVLRPGDHLVIPDDAYGGTFRLIDKVFSQWGISYTAVALSDLDAVRAAITPQTKMIWVETP TNPLLSIADIAGIAGIAAESGLKVLVDNTFASPALQQPLLLGADIVLHSTTKYIGGHSDVVGGALLTNDEELDTAFAFLQ NGSGAVPGPFDAYLTLRGLKTLVVRMQRHSENAAAVAEFLDGHPAIDTVLYPGLPSHPGHDVAAKQMSGFGGMVSVRLHG GPKAAREFCARTGIFILAESLGGVESLIEHPGAMTHASTAGSQLEVPEDLVRLSVGIEDRADLIADLEQALA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-70 | 48 |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 3e-69 | 47 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 1e-51 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Mkms_4221 | YP_940203.1 | cystathionine gamma-synthase | BAC0207 | Protein | 7e-58 | 44 |
